机构

• 上海药物研究所 [27]
• 大连化学物理研究所 [4]
• 昆明植物研究所 [2]
• 化学研究所 [1]
• 成都生物研究所 [1]
• 中国科学院大学 [1]
• 更多

采集方式

• OAI收割 [36]
• iSwitch采集 [1]

内容类型

• 期刊论文 [34]
• 学位论文 [2]
• 会议论文 [1]

发表日期

• 2022 [1]
• 2021 [1]
• 2019 [1]
• 2017 [2]
• 2016 [1]
• 2015 [1]
• 更多

学科主题

• Chemistry [1]
• Pharmacolo... [1]
• Toxicology [1]
• 药物化学 [1]

筛选

浏览/检索结果: 共37条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Natural Product-Inspired Targeted Protein Degraders: Advances and Perspectives 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 28 作者:  Li, Jiao;  Cai, Zhenyu;  Li, Xu-Wen;  Zhuang, Chunlin   |  收藏  |  浏览/下载：18/0  |  提交时间：2022/12/13 Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963 作者:  Liu,Jiangxin;  Wu,Xing-De;  Li,Wenyan;  Yuan,Zaifeng;  Yang,Kun   |  收藏  |  浏览/下载：15/0  |  提交时间：2022/04/02 Pseudolaric acid A  Hsp90 inhibitor  Apoptosis  NMR  Structure-activity relationship  Photoaffinity-based probe  Protein-ligand interaction  MOLECULAR CHAPERONE  PROTEIN  TARGET  CANCER  KINASE  NMR  IDENTIFICATION  SELECTIVITY  BINDING  DESIGN   Amphiphilic drug-drug conjugate for cancer therapy with combination of chemotherapeutic and antiangiogenesis drugs 期刊论文  OAI收割 SCIENCE CHINA-CHEMISTRY, 2019, 页码: 7 作者:  Sun, Mo;  Qian, Qiuhui;  Shi, Leilei;  Xu, Li;  Liu, Qunfang   |  收藏  |  浏览/下载：17/0  |  提交时间：2020/07/01 nanoparticle  combination therapy  cancer treatment  supramolecular chemistry   A comparison report of three advanced methods for drug-cyclodextrin interaction measurements 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2017, 卷号: 134, 页码: 252-258 作者:  Singh, Vikramjeet;  He, Yaping;  Wang, Caifen;  Xu, Jianghui;  Xu, Xiaonan   |  收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08 Drug-cyclodextrins interactions  High performance affinity chromatography  Surface plasmon resonance  Surface plasmon resonance imaging  Kinetic constants  Sparingly soluble drugs   Chemical proteomics reveal CD147 as a functional target of pseudolaric acid B in human cancer cells 期刊论文  OAI收割 CHEMICAL COMMUNICATIONS, 2017, 卷号: 53, 期号: 62, 页码: 8671-8674 作者:  Zhou, Yiqing;  Di, Zhengao;  Li, Weichao;  Xiao, Youli   |  收藏  |  浏览/下载：13/0  |  提交时间：2020/12/09 Modified Release and Improved Stability of Unstable BCS II Drug by Using Cyclodextrin Complex as Carrier To Remotely Load Drug into Niosomes 期刊论文  OAI收割 MOLECULAR PHARMACEUTICS, 2016, 卷号: 13, 期号: 1, 页码: 113-124 作者:  Chi, Liandi;  Wu, Delin;  Li, Zhuo;  Zhang, Minmin;  Liu, Hongchun   |  收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 niosomes  pseudolaric acid B  remote loading  pH gradient  retarded release  enzymatic stability   Dramatic improvement of the solubility of pseudolaric acid B by cyclodextrin complexation: Preparation, characterization and validation 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2015, 卷号: 479, 期号: 2, 页码: 349-356 作者:  Chi, Liandi;  Liu, Ruihao;  Guo, Tao;  Wang, Manli;  Liao, Zuhua   |  收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 Cyclodextrins (CDs)  Pseudolaric acid B (PAB)  Solubilization  Molecular simulation  Validation   MCL-1 Degradation Mediated by JNK Activation via MEKK1/TAK1-MKK4 Contributes to Anticancer Activity of New Tubulin Inhibitor MT189 期刊论文  OAI收割 MOLECULAR CANCER THERAPEUTICS, 2014, 卷号: 13, 期号: 6, 页码: 1480-1491 作者:  Wang, Wei;  Wang, Ying-Qing;  Meng, Tao;  Yi, Jun-Mei;  Huan, Xia-Juan   |  收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 Newly discovered angiogenesis inhibitors and their mechanisms of action 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2012, 卷号: 33, 期号: 9, 页码: 1103-1111 作者:  Miao, Ze-hong;  Feng, Jian-ming;  Ding, Jian   |  收藏  |  浏览/下载：8/0  |  提交时间：2019/01/08 cancer therapy  angiogenesis inhibitor  antiangiogenic mechanism  hypoxia-inducible factor 1 alpha  pseudolaric acid B  AL3810   Pseudolaric acid B-driven phosphorylation of c-Jun impairs its role in stabilizing HIF-1alpha: a novel function-converter model 期刊论文  OAI收割 JOURNAL OF MOLECULAR MEDICINE-JMM, 2012, 卷号: 90, 期号: 8, 页码: 971-981 作者:  Yu, Bing;  Li, Mei-Hong;  Wang, Wei;  Wang, Ying-Qing;  Jiang, Yi   |  收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 c-Jun  Hypoxia inducible factor 1 alpha  JNK  Pseudolaric acid B  Ser63/73 phosphorylation