机构

• 上海药物研究所 [4]
• 合肥物质科学研究院 [3]

采集方式

• OAI收割 [7]

内容类型

• 期刊论文 [7]

发表日期

• 2024 [1]
• 2022 [1]
• 2018 [2]
• 2017 [1]
• 2016 [2]

学科主题

筛选

浏览/检索结果: 共7条，第1-7条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Mass balance, metabolism, and pharmacokinetics of [14C]amdizalisib, a clinical-stage novel oral selective PI3Kδ inhibitor for the treatment of non-hodgkin's lymphoma, in healthy Chinese volunteers 期刊论文  OAI收割 FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15, 页码: 13 作者:  Zhao, Chun-Yang;  Zhang, Li-Jun;  Sun, Chan;  Yu, Cheng-Yin;  Wang, Jian   |  收藏  |  浏览/下载：6/0  |  提交时间：2025/01/06 amdizalisib  PI3K delta kinase  metabolism  mass balance  metabolite identification  pharmacokinetics  safety   BCL-2 inhibitor synergizes with PI3K delta inhibitor and overcomes FLT3 inhibitor resistance in acute myeloid leukaemia 期刊论文  OAI收割 AMERICAN JOURNAL OF CANCER RESEARCH, 2022, 卷号: 12, 期号: 8, 页码: 3829-3842 作者:  Yao, Ming-Yue;  Wang, Ya-Fang;  Zhao, Yu;  Ling, Li-Jun;  He, Ye   |  收藏  |  浏览/下载：29/0  |  提交时间：2022/12/13 Acute myeloid leukaemia  BCL-2  PI3K delta  FLT3  synergistic lethality   Discovery of (S)-2-amino-N-(5-(6-chloro-5-(3-methylphenylsulfonamido)pyridin-3-yl)-4-methylthiazol-2-yl)-3-methylbutanamide (CHMFL-PI3KD-317) as a potent and selective phosphoinositide 3-kinase delta (PI3K delta) inhibitor 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 156, 页码: 831-846 作者:  Liang, Xiaofei;  Li, Feng;  Chen, Cheng;  Jiang, Zongru;  Wang, Aoli   |  收藏  |  浏览/下载：42/0  |  提交时间：2019/12/10 PI3K delta  Kinase inhibitor  Acute myeloid leukemia  Structure-activity relationship   Combined inhibition of PI3K delta and FLT3 signaling exerts synergistic antitumor activity and overcomes acquired drug resistance in FLT3-activated acute myeloid leukemia 期刊论文  OAI收割 CANCER LETTERS, 2018, 卷号: 420, 页码: 49-59 作者:  He, Ye;  Sun, Liping;  Xu, Yongping;  Fu, Li;  Li, Yun   |  收藏  |  浏览/下载：51/0  |  提交时间：2019/01/08 Acute myeloid leukemia  FLT3  PI3K delta  CAL101  Synergistic effect   SAR study of 5-alkynyl substituted quinazolin-4(3H)-ones as phosphoinositide 3-kinase delta (PI3K delta) inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 125, 页码: 1156-1171 作者:  Wei, Manman;  Zhang, Xi;  Wang, Xiang;  Song, Zilan;  Ding, Jian   |  收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08 Chronic lymphocytic leukemia  PI3K delta  Structure-activity relationship  5-Alkynyl  Quinazolinone   Simultaneous inhibition of Vps34 kinase would enhance PI3K delta inhibitor cytotoxicity in the B-cell malignancies 期刊论文  OAI收割 ONCOTARGET, 2016, 卷号: 7, 期号: 33, 页码: 53515-53525 作者:  Liu, Xiaochuan;  Wang, Aoli;  Liang, Xiaofei;  Liu, Juanjuan;  Zou, Fengming 收藏  |  浏览/下载：51/0  |  提交时间：2017/11/21 Pi3k Delta  Vps34  Combination  Chronic Lymphatic Leukemia  Acute Myeloid Leukemia   Characterization of selective and potent PI3K delta inhibitor (PI3KD-IN-015) for B-Cell malignances 期刊论文  OAI收割 ONCOTARGET, 2016, 卷号: 7, 期号: 22, 页码: 32641-32651 作者:  Liu, Xiaochuan;  Wang, Aoli;  Liang, Xiaofei;  Chen, Cheng;  Liu, Juanjuan 收藏  |  浏览/下载：30/0  |  提交时间：2017/11/16 Pi3k Delta  Leukemia  B-cell Malignances  Pi3k  Kinase Inhibitors