中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海生物化学与细胞生... [4]
上海药物研究所 [3]
西北高原生物研究所 [1]
广州生物医药与健康研... [1]
昆明动物研究所 [1]
采集方式
OAI收割 [10]
内容类型
期刊论文 [8]
学位论文 [2]
发表日期
2020 [3]
2019 [2]
2018 [3]
2017 [1]
2013 [1]
学科主题
Developmen... [1]
生物工程 [1]
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Identification of catalytic and non-catalytic activity inhibitors against PRC2-EZH2 complex through multiple high-throughput screening campaigns
期刊论文
OAI收割
CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 页码: 27
作者:
Zhou, Yan
;
Du, Dao-Hai
;
Wang, Jia
;
Cai, Xiao-Qing
;
Deng, Alicia X.
  |  
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2020/07/01
embryonic ectoderm development
Enhancer of zeste homolog 2
fluorescence polarization
high-throughput screening
homogenous time-resolved fluorescence
inhibitor
polycomb repressive complex 2
Ring 1 and YY1 Binding Protein is Expressed in Murine Spermatocytes but Dispensable for Spermatogenesis
期刊论文
OAI收割
GENES, 2020, 卷号: 11, 期号: 1
作者:
He, Zhen
;
Yan, Rong-Ge
;
Zhang, Xiao-Na
;
Yang, Qi-En
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/11/25
Rybp
spermatogenesis
meiosis
germ cells
polycomb group 1
Identification and Assessments of Novel and Potent Small-Molecule Inhibitors of EED-EZH2 Interaction of Polycomb Repressive Complex 2 by Computational Methods and Biological Evaluations
期刊论文
OAI收割
CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 1, 页码: 58-63
作者:
Zhu, Kongkai
;
Du, Daohai
;
Yang, Rui
;
Tao, Hongrui
;
Zhang, Hua
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
polycomb repressive complex 2
EZH2-EED interaction inhibitor
virtual screening
molecular dynamics simulation
c10orf12modulatesprc2histonemethyltransferaseactivityandh3k27me3levels
期刊论文
OAI收割
actapharmacologicasinica, 2019, 卷号: 40, 期号: 11, 页码: 1457
作者:
Shi Yi
;
Ma Honglei
;
Zhuang Youwen
;
Wang Xiaoxi
;
Jiang Yi
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
REPRESSIVE COMPLEX 2
GENOMIC TARGETS
POLYCOMB
PROTEIN
CHROMATIN
RECRUITMENT
JARID2
DIFFERENTIATION
BINDING
METHYLATION
PRC2
C10ORF12
H3K27me3
histone methyltransferase
epigenetic regulation
histone modification
果蝇Abd-B位点中DNA调控元件及其结合蛋白的研究
学位论文
OAI收割
北京: 中国科学院大学, 2019
作者:
鲁丹枫
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/12/17
果蝇Ctcf蛋白,Fab-8绝缘子,染色质屏障活性,多梳响应元件Pres,Transvection
drosophila Ctcf, Fab-8 Insulator, Chromatin Barrier, Polycomb Response Elements (Pres), Transvection, Insulator Bypass, Pts, Hrb87f, anti-Insulator
Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch
期刊论文
OAI收割
JOURNAL OF MOLECULAR BIOLOGY, 2018, 卷号: 430, 期号: 21, 页码: 4245-4259
作者:
Peng, Ling
;
Wang, Longlong
;
Zhang, Yingpei
;
Huang, Ying
;
Dong, Aiwu
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2019/04/28
Stem-cells
H2a Ubiquitylation
Targeting Polycomb
Gene
Recruitment
Expression
Drosophila
Trimethylation
Thaliana
H3k27me3
The E3 Ligase RING1 Targets p53 for Degradation and Promotes Cancer Cell Proliferation and Survival
期刊论文
OAI收割
CANCER RESEARCH, 2018, 卷号: 78, 期号: 2, 页码: 359-371
作者:
Shen, Jiajia
;
Liu, Xiujun
;
Wang, Zhen
;
Li, Pengyu
;
Shao, Xuejing
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2019/04/28
Polycomb-group Proteins
Ubiquitin Ligase
Tumor-suppressor
Prostate-cancer
Stem-cells
Expression
Bmi1
Repression
Regulators
Stability
In vivo CRISPR screening unveils histone demethylase UTX as an important epigenetic regulator in lung tumorigenesis
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 卷号: 115, 期号: 17, 页码: E3978-E3986
作者:
Wu, Qibiao
;
Zhang, Jian
;
Tong, Xinyuan
;
Huang, Hsinyi
;
Tang, Ying
  |  
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2019/04/28
Lysine-4 Methyltransferase Complex
Acute Lymphoblastic-leukemia
K-ras
Cancer
Adenocarcinoma
Polycomb
Cells
Differentiation
Expression
Identification
RNF2在人胚胎干细胞命运调控中的作用研究
学位论文
OAI收割
广州生物院: 中国科学院大学, 2017
作者:
梁泽川
  |  
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2018/12/25
人胚胎干细胞
Polycomb抑制性复合物1
RNF2
CRISPR/Cas9
命运调控
Cbx4 regulates the proliferation of thymic epithelial cells and thymus function
期刊论文
OAI收割
DEVELOPMENT, 2013, 卷号: 140, 期号: 4, 页码: 780-788
作者:
Liu, B
;
Liu, YF
;
Du, YR
;
Mardaryev, AN
;
Yang, W
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2015/07/22
Thymic epithelial cell
Cbx4
Thymic hypoplasia
T-lymphopoiesis
p63 (Trp63)
Polycomb
Epithelial progenitor