中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
数学与系统科学研究院 [8]
上海药物研究所 [6]
新疆理化技术研究所 [5]
计算技术研究所 [4]
自动化研究所 [3]
上海营养与健康研究所 [3]
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期刊论文 [56]
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2024 [1]
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A new paradigm for applying deep learning to protein-ligand interaction prediction
期刊论文
OAI收割
BRIEFINGS IN BIOINFORMATICS, 2024, 卷号: 25, 期号: 3, 页码: 12
作者:
Wang, Zechen
;
Wang, Sheng
;
Li, Yangyang
;
Guo, Jingjing
;
Wei, Yanjie
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/12/06
protein-ligand interaction
scoring function
deep learning
graph neural network
Transcriptional regulation analysis reveals the complexity of metamorphosis in the Pacific oyster (Crassostrea gigas)
期刊论文
OAI收割
MARINE LIFE SCIENCE & TECHNOLOGY, 2023, 页码: 11
作者:
Xu, Fei
;
Deng, Shaoxi
;
Gavriouchkina, Daria
;
Zhang, Guofan
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2024/04/07
Gene regulation network
Indirect development
Lophotrochozoa
Nuclear receptors
Neurohormones
Protein synthesis
Transcription factors
Risk of drug-drug interactions in China's fight against COVID-19 and beyond
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2023, 卷号: 196, 页码: 2
作者:
Zhang, Qingpeng
;
Yang, Jiannan
;
Zeng, Daniel Dajun
;
Feng, Yibin
;
Wong, Ian C. K.
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2024/03/26
Drug interactions
Protein-protein interactions
Network science
COVID-19
Deffini: A family-specific deep neural network model for structure-based virtual screening
期刊论文
OAI收割
COMPUTERS IN BIOLOGY AND MEDICINE, 2022, 卷号: 151, 页码: 8
作者:
Zhou, Dixin
;
Liu, Fei
;
Zheng, Yiwen
;
Hu, Liangjian
;
Huang, Tao
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2023/04/10
Virtual screening
Protein family -specific model
Structure -based
Convolutional neural network
Drug discovery
An inductive graph neural network model for compound-protein interaction prediction based on a homogeneous graph
期刊论文
OAI收割
BRIEFINGS IN BIOINFORMATICS, 2022, 页码: 13
作者:
Wan, Xiaozhe
;
Wu, Xiaolong
;
Wang, Dingyan
;
Tan, Xiaoqin
;
Liu, Xiaohong
  |  
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2022/06/15
compound-protein interaction prediction
homogeneous graph
end-to-end learning
inductive graph neural network
Picture-word order compound protein interaction: Predicting compound-protein interaction using structural images of compounds
期刊论文
OAI收割
JOURNAL OF COMPUTATIONAL CHEMISTRY, 2021, 页码: 10
作者:
Qian, Ying
;
Li, Xuelian
;
Wu, Jian
;
Zhou, Aimin
;
Xu, Zhijian
  |  
收藏
  |  
浏览/下载:104/0
  |  
提交时间:2022/01/04
compound-protein interaction
convolutional neural network (CNN)
drug-drug interaction
image processing
structural images
LsrB, the hub of ABC transporters involved in the membrane damage mechanisms of heavy ion irradiation in Escherichia coli
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, 2021, 页码: 10
作者:
Li, Xin
;
Chen, Lei
;
Zhou, Haitao
;
Gu, Shaobin
;
Wu, Ying
  |  
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/12/13
ABC transporter
biofilm
heavy ion
protein-protein interaction (PPI) network
quorum sensing (QS)
transcriptomic
An Effective Link-Based Clustering Algorithm for Detecting Overlapping Protein Complexes in Protein-Protein Interaction Networks
期刊论文
OAI收割
IEEE TRANSACTIONS ON NETWORK SCIENCE AND ENGINEERING, 2021, 卷号: 8, 期号: 4, 页码: 3275-3289
作者:
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收藏
  |  
浏览/下载:53/0
  |  
提交时间:2022/08/22
Proteins
Clustering algorithms
Biology
Search problems
Partitioning algorithms
Optimization
Protein complex detection
protein-protein interaction network
link-based clustering
network clustering
High Expression Levels of CDK1 and CDC20 in Patients With Lung Squamous Cell Carcinoma are Associated With Worse Prognosis
期刊论文
OAI收割
FRONTIERS IN MOLECULAR BIOSCIENCES, 2021, 卷号: 8
作者:
Deng, Huan
;
Hang, Qingqing
;
Shen, Dijian
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/08/30
lung squamous cell carcinoma
protein-protein interaction network
survival analysis
gene set enrichment analysis
experimental validation
Low expression of CHRDL1 and SPARCL1 predicts poor prognosis of lung adenocarcinoma based on comprehensive analysis and immunohistochemical validation
期刊论文
OAI收割
CANCER CELL INTERNATIONAL, 2021, 卷号: 21
作者:
Deng, Huan
;
Hang, Qingqing
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2021/06/21
Lung adenocarcinoma
Weighted gene coexpression network analysis
Differential coexpression genes
Protein-protein interaction network
Survival analysis