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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [20]
金属研究所 [2]
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OAI收割 [29]
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期刊论文 [29]
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Design, synthesis and pharmacological evaluation of ALK and Hsp90 dual inhibitors bearing resorcinol and 2,4-diaminopyrimidine motifs
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 76-86
作者:
Geng, Kaijun
;
Liu, Hongchun
;
Song, Zilan
;
Zhang, Chi
;
Zhang, Minmin
  |  
收藏
  |  
浏览/下载:190/0
  |  
提交时间:2019/01/08
Heat shock protein 90 (Hsp90)
Tyrosine kinase ALK
Dual inhibitor
Drug resistance
Antiproliferative activity
A negative-feedback function of PKC beta in the formation and accumulation of signaling-active B cell receptor microclusters within B cell immunological synapse
期刊论文
OAI收割
JOURNAL OF LEUKOCYTE BIOLOGY, 2015, 卷号: 97, 期号: 5, 页码: 887-900
作者:
Liu, Ce
;
Zhao, XingWang
;
Xu, LiLing
;
Yi, JunYang
;
Shaheen, Samina
收藏
  |  
浏览/下载:147/0
  |  
提交时间:2016/12/22
PROTEIN-KINASE-C
BRUTONS TYROSINE KINASE
ANTIGEN RECEPTOR
T-CELLS
ACTIVATION
EXPRESSION
BTK
AGAMMAGLOBULINEMIA
POLARIZATION
INITIATION
Chemical Constituents from the Heartwood of Haematoxylon campechianum as Protein Tyrosine Kinase Inhibitors
期刊论文
OAI收割
CHEMISTRY & BIODIVERSITY, 2014, 卷号: 11, 期号: 5, 页码: 776-783
作者:
Lin, Li-Gen
;
Xie, Hua
;
Wang, Yi-Tao
;
Ding, Jian
;
Ye, Yang
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
Haematoxylon campechianum
Protein tyrosine kinases (PTKs)
Epihematoxylol B
Homoisoflavonoids
Hematoxylol B
10-O-methyl-
Kinase insert domain receptor (KDR)
Energetic factors determining the binding of type I inhibitors to c-Met kinase: experimental studies and quantum mechanical calculations
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 11, 页码: 1475-1483
作者:
Yu, Zhe
;
Ma, Yu-chi
;
Ai, Jing
;
Chen, Dan-qi
;
Zhao, Dong-mei
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
receptor tyrosine kinase
type I c-Met inhibitor
cancer
quantum chemistry
protein-ligand interaction
symmetry-adapted perturbation theory (SAPT)
Energetic factors determining the binding of type I inhibitors to c-Met kinase: experimental studies and quantum mechanical calculations
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 11, 页码: 1475-1483
作者:
Yu Zhe
;
Ma Yuchi
;
Ai Jing
;
Chen Danqi
;
Zhao Dongmei
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/02/02
SULFUR-PI INTERACTIONS
PERTURBATION-THEORY
SUBSTITUENTS
SANDWICH
BENZENE
PATHWAY
receptor tyrosine kinase
type I c-Met inhibitor
cancer
quantum chemistry
protein-ligand interaction
symmetry-adapted perturbation theory (SAPT)
Energetic factors determining the binding of type I inhibitors to c-Met kinase: experimental studies and quantum mechanical calculations
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 11, 页码: 1475-1483
作者:
Yu Zhe
;
Ma Yuchi
;
Ai Jing
;
Chen Danqi
;
Zhao Dongmei
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/02/02
SULFUR-PI INTERACTIONS
PERTURBATION-THEORY
SUBSTITUENTS
SANDWICH
BENZENE
PATHWAY
receptor tyrosine kinase
type I c-Met inhibitor
cancer
quantum chemistry
protein-ligand interaction
symmetry-adapted perturbation theory (SAPT)
Identification and biophysical assessment of the molecular recognition mechanisms between the human haemopoietic cell kinase Src homology domain 3 and ALG-2-interacting protein X
期刊论文
OAI收割
Biochemical Journal, 2010, 卷号: 431, 页码: 93-102
X. L. Shi, S. Opi, A. Lugari, A. Restouin, T. Coursindel, I. Parrot, J. Perez, E. Madore, P. Zimmermann, J. Corbeil, M. D. Huang, S. T. Arold, Y. Collette and X. Morelli
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2012/11/02
apoptosis-linked gene 2-interacting protein X (Alix)
haemopoietic cell
kinase (Hck)
protein-protein interaction
Src homology 3 domain (SH3
domain)
Src family kinase (SFK)
hiv-1 nef protein
hck sh3 domain
signal-transduction
crystal-structure
tyrosine kinases
family kinases
c-src
alix
binding
reveals
Actinomycetes for Marine Drug Discovery Isolated from Mangrove Soils and Plants in China
期刊论文
OAI收割
MARINE DRUGS, 2009, 卷号: 7, 期号: 1, 页码: 24-44
作者:
Hong, Kui
;
Gao, An-Hui
;
Xie, Qing-Yi
;
Gao, Hao
;
Zhuang, Ling
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
Mangroves
actinomycete diversity
marine drug discovery
high-throughput screening
growth inhibition
protein tyrosine phosphatase 1B
aurora kinase A
caspase 3