中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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海洋研究所 [146]
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Development of 3-arylaminothiophenic-2-carboxylic acid derivatives as new FTO inhibitors showing potent antileukemia activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 289, 页码: 17
作者:
Zhang, Deyan
;
Liu, Lu
;
Li, Ming
;
Hu, Xinyi
;
Zhang, Xi
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/04/24
RNA modification
N 6-methyladenosine
Demethylase FTO
Structure-activity relationship
Antileukemia
Potential roles of
LMNA
in promoting longevity for larger Argopecten scallops
期刊论文
OAI收割
AQUACULTURE, 2025, 卷号: 600, 页码: 13
作者:
Zhao, Yang
;
Ning, Junhao
;
Wang, Quanchao
;
Liu, Guilong
;
Xu, Xin
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/05/09
Argopecten scallops
LMNA-SIRT1 interaction
RNA interference
Longevity
Identification of CDKN1A as a potential key risk factor in MASLD progression
期刊论文
OAI收割
FASEB JOURNAL, 2025, 卷号: 39, 期号: 7, 页码: 15
作者:
Deng, Lijuan
;
Deng, Jianxin
;
Luo, Liping
;
Yang, Hongjia
;
Sun, Mengxue
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/05/27
biomarkers
CDKN1A
liver
MASLD
RNA-seq
A patenting perspective of fat mass and obesity associated protein (FTO) inhibitors: 2017-present
期刊论文
OAI收割
EXPERT OPINION ON THERAPEUTIC PATENTS, 2025, 页码: 10
作者:
Dong, Ze
;
Huang, Yue
;
Xia, Wenyang
;
Liao, Yonggang
;
Yang, Cai-Guang
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/05/27
RNA methylation
FTO inhibitors
anticancer
patents
obesity
Discovery of Covalent and Cell-Active ALKBH5 Inhibitors with Potent Antileukemia Effects
In Vivo
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 9
作者:
Wu, Hengbo
;
Lai, Gan-Qiang
;
Cheng, Ruixiang
;
Huang, Hui
;
Wang, Ju
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/04/24
RNA epigenetics
N
(6)-methyladenosine
ALKBH5
covalent inhibitor
antileukemia
A ready-to-use RNA delivery platform modulated by metal ions
期刊论文
OAI收割
CHEMICAL ENGINEERING JOURNAL, 2025, 卷号: 506, 页码: 15
作者:
Qin, Zhaojian
;
Jiang, Yongzhuo
;
Tao, Peng
;
Liu, Haifeng
;
Zhong, Han
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/04/01
RNA delivery
Ready-to-use delivery
Metallized-ionizable liposome
The role of dsRNA A-to-I editing catalyzed by ADAR family enzymes in the pathogeneses
期刊论文
OAI收割
RNA BIOLOGY, 2024, 卷号: 21, 期号: 1, 页码: 52-69
作者:
Liu, Wanqing
;
Wu, Yufan
;
Zhang, Tong
;
Sun, Xiaobo
;
Guo, Dean
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/11/26
Double Stranded RNA (dsRNA) Adenosine-to-Inosine (A-to-I) Editing
Adenosine Deaminases (ADAR) Enzyme
Pathogenesis
RNA Modification
Tumorigenicity
Nanotechnology used for siRNA delivery for the treatment of neurodegenerative diseases: Focusing on Alzheimer's disease and Parkinson's disease
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2024, 卷号: 666, 页码: 15
作者:
Li, Yan
;
Zhang, Jiahui
;
Ma, Boqin
;
Yu, Wenjun
;
Xu, Meixia
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/11/26
Neurodegenerative diseases
Brain drug delivery
Therapeutic drug
Small interfering RNA
Nanotechnology
DeepFusion: A deep bimodal information fusion network for unraveling protein-RNA interactions using in vivo RNA structures
期刊论文
OAI收割
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2024, 卷号: 23, 页码: 617-625
作者:
Qiao, Yixuan
;
Yang, Rui
;
Liu, Yang
;
Chen, Jiaxin
;
Zhao, Lianhe
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/05/20
Information fusion
Deep learning
RNA -binding proteins
In vivo RNA structures
Motifs
Discovery of a potent PROTAC degrader for RNA demethylase FTO as antileukemic therapy
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 12, 页码: 5382-5392
作者:
Liu, Lu
;
Qiu, Yuanlai
;
Suo, Yuying
;
Tong, Siyao
;
Wang, Yiqing
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/04/01
N 6-Methyladenosine
FTO
PROTAC
RNA epigenetics
Antileukemia