中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
上海神经科学研究所 [1]
新疆理化技术研究所 [1]
心理研究所 [1]
上海生物化学与细胞生... [1]
采集方式
OAI收割 [12]
内容类型
期刊论文 [12]
发表日期
2024 [1]
2019 [1]
2017 [2]
2014 [2]
2011 [1]
2009 [1]
更多
学科主题
Neuroscien... [1]
Neuroscien... [1]
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Genetic polymorphisms in the 5-HT and endocannabinoid systems moderate the association between childhood trauma and burnout in the general occupational population
期刊论文
OAI收割
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 2024, 卷号: 134, 页码: 10
作者:
Li, Yuling
;
Wang, Lei
;
He, Yingyi
;
Zhu, Shuanggen
;
He, Shu-Chang
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/08/12
Burnout
Serotonin (5-HT)
HTR2A gene
FAAH gene
Childhood trauma
Synthesis and Biological Evaluation of Five-Atom-Linker-Based Arylpiperazine Derivatives with an Atypical Antipsychotic Profile
期刊论文
OAI收割
CHEMMEDCHEM, 2019, 页码: 11
作者:
Wu, Chunhui
;
Wang, Yu
;
Yang, Feipu
;
Shi, Wenqiang
;
Wang, Zhen
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/07/01
D-2
5-HT1A
5-HT2A
serotonin
SERT
PCP-induced hyperactivity
Synthesis and biological investigation of tetrahydropyridopyrimidinone derivatives as potential multireceptor atypical antipsychotics
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 17, 页码: 4904-4916
作者:
Xiamuxi, Hainimu
;
Wang, Zhen
;
Li, Jianfeng
;
Wang, Yu
;
Wu, Chunhui
  |  
收藏
  |  
浏览/下载:140/0
  |  
提交时间:2019/01/08
Dopamine
Serotonin
Multireceptor
Atypical antipsychotic
5-HT1A
Synthesis and biological investigation of tetrahydropyridopyrimidinone derivatives as potential multireceptor atypical antipsychotics
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 17, 页码: 4904-4916
作者:
Xiamuxi, H (Xiamuxi, Hainimu)
;
Wang, Z (Wang, Zhen)
;
Li, JF (Li, Jianfeng)
;
Wang, Y (Wang, Yu)
  |  
收藏
  |  
浏览/下载:127/0
  |  
提交时间:2017/10/31
Dopamine
Serotonin
Multireceptor
Atypical Antipsychotic
5-ht1a
Structural manipulation on the catecholic fragment of dopamine D-1 receptor agonist 1-phenyl-N-methyl-benzazepines
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 85, 页码: 16-26
作者:
Zhang, Jing
;
Huang, Jiye
;
Song, Zilan
;
Guo, Lin
;
Cai, Wenxian
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
Arylbenzazepine
Dopamine receptor
Serotonin 5-HT2A receptor
Structural modification
Catecholic fragment
Dual Ligands Targeting Dopamine D-2 and Serotonin 5-HT1A Receptors as New Antipsychotical or Anti-Parkinsonian Agents
期刊论文
OAI收割
CURRENT MEDICINAL CHEMISTRY, 2014, 卷号: 21, 期号: 4, 页码: 437-457
作者:
Ye, Na
;
Song, Zilan
;
Zhang, Ao
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Atypical antipsychotics
dopamine D-2 receptor
dual ligands
Parkinson's disease
Schizophrenia
Serotonin 5-HT1A receptor
Classification of 5-HT_(1A) receptor agonists and antagonists using GA-SVM method
期刊论文
OAI收割
Acta Pharmacologica Sinica, 2011, 卷号: 32, 期号: 11, 页码: 1424
作者:
Zhu Xuelian
;
Cai Haiyan
;
Xu Zhijian
;
Wang Yong
;
Wang Heyao
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
VIVO PHARMACOLOGICAL EVALUATION
SEROTONIN TRANSPORTER AFFINITY
IN-VITRO
DUAL 5-HT1A
REUPTAKE INHIBITORS
LIGANDS
POTENT
DERIVATIVES
DISCOVERY
ANALOGS
5-HT1A receptor
support vector machine
genetic algorithm
agonist
antagonists
'Click' D-1 receptor agonists with a 5-HT1A receptor pharmacophore producing D-2 receptor activity
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2009, 卷号: 17, 期号: 14, 页码: 4873-4880
作者:
Zhang, Jing
;
Zhang, Hai
;
Cai, Wenxian
;
Yu, Leiping
;
Zhen, Xuechu
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Arylbenzazepine
Arylpiperazine
Click reaction
Dopamine receptor
Serotonin 5-HT1A receptor
Fluoxetine potentiates GABAergic IPSCs in rat hippocampal neurons
期刊论文
OAI收割
NEUROSCIENCE LETTERS, 2008, 卷号: 442, 期号: 1, 页码: 24-29
Ye, Zeng-You
;
Zhou, Ke-Qing
;
Xu, Tian-Le(徐天乐)
;
Zhou, Jiang-Ning
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2012/07/23
GABAergic hypothesis
whole-cell patch-clamp recording
antidepressant
neurotransmission
5-HT
GAMMA-AMINOBUTYRIC-ACID
MAGNETIC-RESONANCE-SPECTROSCOPY
DEPRESSED-PATIENTS
PLASMA-CONCENTRATIONS
AFFECTIVE-ILLNESS
MAJOR DEPRESSION
MOOD DISORDERS
GABA
SEROTONIN
NORFLUOXETINE
Pharmacophore-directed Homology Modeling and Molecular Dynamics Simulation of G Protein-coupled Receptor: Study of Possible Binding Modes of 5-HT_(2C) Receptor Agonists
期刊论文
OAI收割
Acta Biochimica et Biophysica Sinica, 2007, 卷号: 39, 期号: 6, 页码: 413
作者:
Zhili ZUO
;
Gang CHEN
;
Xiaomin LUO
;
Chummok PUAH
;
Weiliang ZHU
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/07/01
PARTICLE MESH EWALD
IDENTIFICATION
SEROTONIN
WEIGHT
5-HYDROXYTRYPTAMINE(2A)
ACTIVATION
KETANSERIN
RHODOPSIN
PROGRAM
BILAYER
5-HT2C receptor
Flexi-Dock
G protein-coupled receptor
homology modeling
molecular dynamics simulation