中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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合肥物质科学研究院 [65]
上海药物研究所 [43]
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期刊论文 [200]
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A shape complementarity strategy based on NCA029 enables potent HsClpP agonists for the treatment of small cell lung carcinoma
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 299, 页码: 26
作者:
Li, Linjie
;
Luo, Baozhu
;
Wang, Xudong
;
Jian, Zhongyu
;
Liu, Hong
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/12/04
HsClpP
Shape complementarity
Small cell lung carcinoma
Pharmacokinetics, mass balance, and metabolism of [
14
C]SAF-189s, a potent anaplastic lymphoma kinase/c-ROS proto-oncogene 1 inhibitor in humans: Metabolism potentially affected by interaction of cytochrome P450 enzymes and intestinal microbiota
期刊论文
OAI收割
DRUG METABOLISM AND DISPOSITION, 2025, 卷号: 53, 期号: 9, 页码: 14
作者:
Yang, Ming
;
Diao, Lei
;
Yan, Shu
;
Tan, Yan
;
Liu, Donghui
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/12/04
[C-14]SAF-189s
SAF-189s metabolism and pharmacokinetics
Non-small cell lung cancer
ALK/ROS1 inhibitor
Intestinal flora
P450 enzymes
High Efficiency Production of Functional Small Extracellular Vesicles through Cellular Self-Motivation
期刊论文
OAI收割
NANO LETTERS, 2025, 卷号: 25, 期号: 16, 页码: 6471-6480
作者:
Wang, Chen
;
Zhao, Xinyu
;
Yan, Tianhao
;
Zhang, Shuxin
;
Li, Xiaoru
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2025/06/23
Small extracellularvesicle
Piezoionic hydrogel
Traction force
Cellular self-stimulation
Stem cell therapy
Real-world data on ALK rearrangement test in Chinese advanced non-small cell lung cancer (RATICAL): a nationwide multicenter retrospective study
期刊论文
OAI收割
CANCER COMMUNICATIONS, 2024
作者:
Li, Lin
;
Li, Wencai
;
Wu, Chunyan
;
Xi, Yanfeng
;
Guo, Lei
  |  
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2024/11/22
anaplastic lymphoma kinase
diagnosis
gene fusion
non-small cell lung cancer
Real-world data on ALK rearrangement test in Chinese advanced non-small cell lung cancer (RATICAL): a nationwide multicenter retrospective study
期刊论文
OAI收割
CANCER COMMUNICATIONS, 2024
作者:
Li, Lin
;
Li, Wencai
;
Wu, Chunyan
;
Xi, Yanfeng
;
Guo, Lei
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2024/11/22
anaplastic lymphoma kinase
diagnosis
gene fusion
non-small cell lung cancer
RPTOR blockade suppresses brain metastases of NSCLC by interfering the ceramide metabolism via hijacking YY1 binding
期刊论文
OAI收割
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2024, 卷号: 43, 期号: 1, 页码: 15
作者:
Lin, Ying
;
Wu, Yun
;
Zhang, Qiangzu
;
Tu, Xunwei
;
Chen, Sufang
  |  
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2024/05/20
Non-small cell lung cancer
Brain metastasis
RPTOR
SPHK2
S1P
Deep learning for predicting major pathological response to neoadjuvant chemoimmunotherapy in non-small cell lung cancer: A multicentre study
期刊论文
OAI收割
EBIOMEDICINE, 2022, 卷号: 86, 页码: 13
作者:
She, Yunlang
;
He, Bingxi
;
Wang, Fang
;
Zhong, Yifan
;
Wang, Tingting
  |  
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2023/02/22
Deep learning
Neoadjuvant chemoimmunotherapy
Major pathological response
Non-small cell lung cancer
The effect of EGFR-TKIs on survival in advanced non-small-cell lung cancer with EGFR mutations: A real-world study
期刊论文
OAI收割
CANCER MEDICINE, 2022
作者:
Yu, Xiaoqing
;
Si, Jinfei
;
Wei, Jingwen
;
Wang, Yanling
;
Sun, Yan
  |  
收藏
  |  
浏览/下载:174/0
  |  
提交时间:2022/12/23
EGFR-TKIs
non-small cell lung cancer (NSCLC)
real-world study
survival outcome
Hypoxia-inducible factor 1-alpha is a driving mechanism linking chronic obstructive pulmonary disease to lung cancer
期刊论文
OAI收割
FRONTIERS IN ONCOLOGY, 2022, 卷号: 12
作者:
Xu, Yuan-rui
;
Wang, An-long
;
Li, Ya-qing
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2022/12/23
chronic obstructive pulmonary disease
lung cancer
non-small cell lung cancer
hypoxia-inducible factor 1-alpha
hypoxia-inducible factor 1
Darinaparsin (ZIO-101) enhances the sensitivity of small-cell lung cancer to PARP inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Cao, Guo-Zhen
;
Ma, Li-Ying
;
Zhang, Zong-Hui
;
Wang, Xiao-Lin
;
Hua, Jing-Han
  |  
收藏
  |  
浏览/下载:91/0
  |  
提交时间:2022/12/22
small-cell lung cancer
H3
3
PARP1
PARP inhibitor
darinaparsin
combination treatment