中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [13]
金属研究所 [2]
大连化学物理研究所 [2]
昆明植物研究所 [2]
成都生物研究所 [1]
采集方式
OAI收割 [20]
内容类型
期刊论文 [20]
发表日期
2024 [1]
2022 [1]
2018 [2]
2017 [3]
2013 [1]
2012 [6]
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学科主题
Agricultur... [1]
Chemistry [1]
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Platanosides from Platanus x acerifolia: New molecules, SAR, and target validation of a strong lead for drug-resistant bacterial infections and the associated sepsis
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:
Wu, Xi-Ying
;
Zhao, Ze-Yu
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2024/03/06
Platanus x acerifolia
Platanosides
Molecular ion networking (MoIN)
Antibacterial
Staphylococcus aureus
Enterococcus faecium
Structure -activity relationship (SAR)
Molecular docking
Target validation
Review of Voltage-gated Calcium Channel alpha 2 delta Subunit Ligands for the Treatment of Chronic Neuropathic Pain and Insight into Structure-activity Relationship (SAR) by Pharmacophore Modeling
期刊论文
OAI收割
CURRENT MEDICINAL CHEMISTRY, 2022, 卷号: 29, 期号: 30, 页码: 5097-5112
作者:
Chen, Yuting
;
Wu, Qingqing
;
Jin, Zhengsheng
;
Qin, Yanlan
;
Meng, Fancui
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/11/11
Voltage-gated calcium channel
alpha 2 delta subunit
neuropathic pain
structure-activity relationship (SAR)
pharmacophore modeling
gabapentinoids
Design, synthesis, and fungicidal activity of novel 1,3,4-oxadiazole derivatives
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2018, 卷号: 29, 期号: 6, 页码: 915-918
作者:
Yu Fuqiang
;
Guan Aiying
;
Li Mengru
;
Hu Lan
;
Li Xiaowu
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2021/02/02
INSECTICIDAL ACTIVITIES
SAR
1,3,4-Oxadiazole derivatives
Intermediate derivatization method
Rice sheath blight
Sorghum anthracnose
Structure-activity relationship
Design, synthesis, and fungicidal activity of novel 1,3,4-oxadiazole derivatives
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2018, 卷号: 29, 期号: 6, 页码: 915-918
作者:
Yu Fuqiang
;
Guan Aiying
;
Li Mengru
;
Hu Lan
;
Li Xiaowu
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2021/02/02
INSECTICIDAL ACTIVITIES
SAR
1,3,4-Oxadiazole derivatives
Intermediate derivatization method
Rice sheath blight
Sorghum anthracnose
Structure-activity relationship
Structure-Activity Relationships of Pentacyclic Triterpenoids as Potent and Selective Inhibitors against Human Carboxylesterase 1
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8
作者:
Zou, Li-Wei
;
Dou, Tong-Yi
;
Wang, Ping
;
Lei, Wei
;
Weng, Zi-Miao
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2017/10/29
Human Carboxylesterase 1 (Hce1)
Ursolic Acid
Oleanolic Acid
Structure-activity Relationship (Sar)
Selective Inhibitors
The Second-generation of Highly Potent Hepatitis C Virus (HCV) NS3/4A Protease Inhibitors: Evolutionary Design Based on Tailor-made Amino Acids, Synthesis and Major Features of Bio-activity
期刊论文
OAI收割
CURRENT PHARMACEUTICAL DESIGN, 2017, 卷号: 23, 期号: 30, 页码: 4493-4554
作者:
Wang, Shuni
;
Wang, Yibing
;
Wang, Jiang
;
Sato, Tatsunori
;
Izawa, Kunisuke
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/01/08
Hepatitis C virus (HCV)
pandemic
direct-acting antiviral agents (DAAs)
NS3/4A protease inhibitor
tailor-made amino acids
structure-activity relationship (SAR)
asymmetric synthesis
ring-closing metathesis (RCM)
Development of Selective Cyclin-Dependent Kinase 4 Inhibitors for Antineoplastic Therapies
期刊论文
OAI收割
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2017, 卷号: 17, 期号: 5, 页码: 646-657
作者:
Guan, Haixing
;
Du, Yongli
;
Han, Weiwei
;
Shen, Jingkang
;
Li, Qunyi
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
Anti-cancer agents
cell cycle
clinical trials
cyclin-dependent kinases 4
selective inhibitors
structure activity relationship (SAR)
Evaluation of anti-HCV activity and SAR study of (+)-lycoricidine through targeting of host heat-stress cognate 70 (Hsc70)
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 9, 页码: 2679-2682
作者:
Chen, Duo-Zhi
;
Jiang, Jian-Dong
;
Zhang, Ke-Qing
;
He, Hong-Ping
;
Di, Ying-Tong
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2013/06/08
(+)-Lycoricidine
Heat-stress cognate 70 (Hsc70)
Down-regulators
Structure-activity relationship (SAR)
Anti-HCV activity
Synthesis and structure-activity relationship studies of cytotoxic vinorelbine amide analogues
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 24, 页码: 7547-7550
作者:
Hu, Lingjun
;
Song, Weibin
;
Meng, Yuhui
;
Guo, Dean
;
Liu, Xuan
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Vinorelbine
C-22 amide analogues
Tubulin inhibitor
Structure-activity relationship (SAR)
Cytotoxicity
Multisubstituted quinoxalines and pyrido[2,3-d]pyrimidines: Synthesis and SAR study as tyrosine kinase c-Met inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 20, 页码: 6368-6372
作者:
Wu, Kui
;
Ai, Jing
;
Liu, Qiufeng
;
Chen, TianTian
;
Zhao, Ailing
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/01/08
c-Met kinase
3,5-Diamino-7-trifluoroquinoline
hERG
Antitumor activity
Structure-activity relationship (SAR)