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Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共229条，第1-10条 帮助

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Discovery of a CB2 and 5-HT1A receptor dual agonist for the treatment of depression and anxiety 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 20
作者:  Yang, Wenjiao;  Gong, Xudong;  Sun, Haiguo;  Wu, Chunhui;  Suo, Jin
  |  收藏  |  浏览/下载：7/0  |  提交时间：2024/03/06
Platanosides from Platanus x acerifolia: New molecules, SAR, and target validation of a strong lead for drug-resistant bacterial infections and the associated sepsis 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:  Wu, Xi-Ying;  Zhao, Ze-Yu;  Osman, Ezzat E. A.;  Wang, Xiao-Juan;  Choo, Yeun-Mun
  |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/06
Discovery, Optimization, and Evaluation of Novel Pyridin-2(1H)-one Analogues as Potent TRK Inhibitors for Cancer Treatment 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183
作者:  Xu, Zichao;  Peng, Xia;  Zhang, Renjie;  Ji, Yinchun;  You, Mengke
  |  收藏  |  浏览/下载：10/0  |  提交时间：2024/02/27
Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 263, 页码: 21
作者:  Zhang, Hongjin;  Lin, Guohao;  Jia, Suyun;  Zhang, Ying;  Wu, Jianbo
  |  收藏  |  浏览/下载：5/0  |  提交时间：2024/01/26
Synthesis, evaluation and molecular dynamics study of human toll-like receptor 2/6 specific monoacyl lipopeptides as candidate immunostimulants 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 141, 页码: 17
作者:  Zhu, Yueyue;  Liu, Bo;  Chen, Zonglong;  Wang, Xianyang;  Wang, Yujie
  |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/08
Modular Biomimetic Strategy Enabled Discovery of Simplified Pseudo-Natural Macrocyclic P-Glycoprotein Inhibitors Capable of Overcoming Multidrug Resistance 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 4, 页码: 2550-2565
作者:  Liu, Bo;  Yu, Xueni;  Liu, Liping;  Wang, Lei;  Wang, Jie
  |  收藏  |  浏览/下载：2/0  |  提交时间：2024/03/27
Development of a series of quinazoline-2,5-diamine derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 20
作者:  Shi, Huanyu;  Tang, Haotian;  Li, Yan;  Chen, Danqi;  Liu, Tongchao
  |  收藏  |  浏览/下载：19/0  |  提交时间：2023/04/10
Design, Synthesis, and Biological Evaluation of 2-Aminothiazole Derivatives as Novel Checkpoint Kinase 1 (CHK1) Inhibitors 期刊论文  OAI收割
CHEMMEDCHEM, 2023, 页码: 19
作者:  Deng, Minjie;  Wang, Peipei;  Long, Xiubing;  Xu, Gaoya;  Wang, Chang
  |  收藏  |  浏览/下载：13/0  |  提交时间：2023/04/10
Hiding Payload Inside the IgG Fc Cavity Significantly Enhances the Therapeutic Index of Antibody-Drug Conjugates 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 16
作者:  Shi, Wei;  Zhang, Jianxin;  Liu, Liya;  Li, Wanzhen;  Liu, Zhi
  |  收藏  |  浏览/下载：16/0  |  提交时间：2023/04/10
Study on structure-activity relationship (SAR) of simplified mirogabalin derivatives as voltage-gated calcium channel alpha 2 delta ligands for the treatment of chronic neuropathic pain 期刊论文  OAI收割
MEDICINAL CHEMISTRY RESEARCH, 2022, 页码: 26
作者:  Zhang, Yuanwen;  Zheng, Yueming;  Wu, Qingqing;  Tian, Fuyun;  Ma, Chuanjun
  |  收藏  |  浏览/下载：24/0  |  提交时间：2023/04/10