机构

• 上海药物研究所 [15]
• 广州生物医药与健康研... [3]
• 合肥物质科学研究院 [3]
• 金属研究所 [2]

采集方式

• OAI收割 [23]

内容类型

• 期刊论文 [20]
• 学位论文 [3]

发表日期

• 2022 [2]
• 2021 [1]
• 2020 [3]
• 2018 [6]
• 2017 [5]
• 2015 [1]
• 更多

学科主题

• 药物化学 [3]

筛选

浏览/检索结果: 共23条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 A Phase 2 Study of Befotertinib in Patients with EGFR T790M Mutated NSCLC after Prior EGFR TKIs 期刊论文  OAI收割 JOURNAL OF THORACIC ONCOLOGY, 2022, 卷号: 17 作者:  Lu, S.;  Zhang, Y.;  Zhang, G.;  Zhou, J.;  Cang, S.   |  收藏  |  浏览/下载：118/0  |  提交时间：2022/12/23 third-generation EGFR-TKI  befotertinib  T790M   Impact of clinical and molecular features on efficacy and outcome of patients with non-small cell lung cancer receiving second-line osimertinib 期刊论文  OAI收割 BMC CANCER, 2022, 卷号: 22 作者:  Jin, Ying;  Lin, Chen;  Shi, Xun;  He, Qiong;  Yan, Junrong   |  收藏  |  浏览/下载：85/0  |  提交时间：2022/12/23 Clinical and molecular features  Efficacy and outcome  EGFR T790M mutation  Non-small-cell lung cancer  Osimertinib   The correlation between the abundance of EGFR T790M mutation and osimertinib response in advanced non-small cell lung cancer 期刊论文  OAI收割 TRANSLATIONAL CANCER RESEARCH, 2021, 卷号: 10 作者:  Pan, Guoqiang;  Chen, Kaiyan;  Yu, Xiaoqing;  Sheng, Jiamin;  Fan, Yun   |  收藏  |  浏览/下载：55/0  |  提交时间：2021/11/01 Non-small cell lung cancer (NSCLC)  T790M abundance  droplet digital PCR (ddPCR)  next generation sequencing (NGS)  osimertinib   Safety, Clinical Activity, and Pharmacokinetics of Al flutinib (AST2818) in Patients With Advanced NSCLC With EGFR T790M Mutation 期刊论文  OAI收割 JOURNAL OF THORACIC ONCOLOGY, 2020, 卷号: 15, 期号: 6, 页码: 1015-1026 作者:  Shi, Yuankai;  Zhang, Shucai;  Hu, Xingsheng;  Feng, Jifeng;  Ma, Zhiyong   |  收藏  |  浏览/下载：103/0  |  提交时间：2020/12/24 Alflutinib  NSCLC  EGFR T790M mutation  Efficacy  Safety   Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance 期刊论文  OAI收割 MOLECULAR CANCER, 2020, 卷号: 19, 期号: 1, 页码: 15 作者:  Zhang, Tao;  Qu, Rong;  Chan, Shingpan;  Lai, Mengzhen;  Tong, Linjiang   |  收藏  |  浏览/下载：91/0  |  提交时间：2020/07/01 Non-small cell lung cancer (NSCLC)  EGFR T790M  Small-molecule inhibitor  Drug resistance  Ack1   BBB-penetrating codelivery liposomes treat brain metastasis of non-small cell lung cancer with EGFR(T790M) mutation 期刊论文  OAI收割 THERANOSTICS, 2020, 卷号: 10, 期号: 14, 页码: 6122-6135 作者:  Yin, Weimin   |  收藏  |  浏览/下载：95/0  |  提交时间：2020/07/01 brain targeting delivery  tumor-associated macrophage  non-small cell lung cancer (NSCLC)  drug resistance  tyrosine kinase inhibitors (TKI)  EGFR T790M mutation   Remodeling Tumor-Associated Macrophages and Neovascularization Overcomes EGFR(T790M)-Associated Drug Resistance by PD-L1 Nanobody-Mediated Codelivery 期刊论文  OAI收割 SMALL, 2018, 卷号: 14, 期号: 47 作者:  Yin, Weimin;  Yu, Xiaolu;  Kang, Xuejia;  Zhao, Yuge;  Zhao, Pengfei   |  收藏  |  浏览/下载：115/0  |  提交时间：2019/01/08 antiangiogenesis  EGFR(T790M) mutation  PD-L1 nanobody  simvastatin  tumor-associated macrophage   Discovery of novel 2,4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 298-306 作者:  Yan, Qi;  Chen, Yuzhe;  Tang, Baiyou;  Xiao, Qiang;  Qu, Rong   |  收藏  |  浏览/下载：84/0  |  提交时间：2019/01/08 EGFR inhibitors  Pyrimidine derivatives  Mutant selective inhibitors  AZD9291  T790M   YL143, a novel mutant selective irreversible EGFR inhibitor, overcomes EGFR(L858R, T790M)-mutant resistance in vitro and in vivo 期刊论文  OAI收割 CANCER MEDICINE, 2018, 卷号: 7, 期号: 4, 页码: 1430-1439 作者:  Zhang, Zhang;  Zou, Jian;  Yu, Lei;  Luo, Jinfeng;  Li, Yan   |  收藏  |  浏览/下载：79/0  |  提交时间：2019/01/08 EGFR inhibitor  lung cancer  pharmacokinetic  selectively  T790M mutation   Synthesis and Biological Activities of Novel 2-Aminobenzimidazoles EGFR~(T790M) Inhibitors 期刊论文  OAI收割 Chinese Journal of Synthetic Chemistry, 2018, 卷号: 26, 期号: 9, 页码: 637-646 作者:  Duan Jingyi;  Zhang Yinyong;  Qian Anran;  Tong Linjiang;  Xie Hua   |  收藏  |  浏览/下载：39/0  |  提交时间：2019/01/08 1-fluoro-2-nitroarene  trans-4-aminocyclohexanol hydrochloride  2-aminobenzimidazole  EGFR~(T790M) inhibitor  synthesis  biological activity