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Chinese Academy of Sciences Institutional Repositories Grid
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Exploration of the potential association between GLP-1 receptor agonists and suicidal or self-injurious behaviors: a pharmacovigilance study based on the FDA Adverse Event Reporting System database
期刊论文
OAI收割
BMC MEDICINE, 2024, 卷号: 22, 期号: 1, 页码: 13
作者:
Zhou, Jianxing
;
Zheng, You
;
Xu, Baohua
;
Long, Songjun
;
Zhu, Li-e
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2024/03/25
GLP-1RAs
Suicidal or self-injurious behaviors
Pharmacovigilance
FAERS database
Type 2 diabetes
Obesity
Structure-based development of potent and selective type-II kinase inhibitors of RIPK1
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334
作者:
Qin, Ying
;
Li, Dekang
;
Qi, Chunting
;
Xiang, Huaijiang
;
Meng, Huyan
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/03/06
RIPK1
Necroptosis
Type-II kinase inhibitors
Rational design
Lead optimization
Structure-activity relationship
Anti-inflammation
Preclinical drug discovery
Autoimmune diseases: targets, biology, and drug discovery
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Li, Shu-jie
;
Wu, Yan-li
;
Chen, Juan-hua
;
Shen, Shi-yi
;
Duan, Jia
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/01/26
autoimmune disease
autoantigen
immunotherapy
type 1 diabetes
insulin
drug discovery
Scalarane sesterterpenes from the South China Sea sponge Hyrtios erecta and their PTP1B inhibitory activity
期刊论文
OAI收割
TETRAHEDRON, 2023, 卷号: 137, 页码: 5
作者:
Sun, Li-Li
;
Shen, Yi-Ran
;
Li, Jia
;
Wang, Jian-Rong
;
Li, Xu-Wen
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2023/10/17
Sponge
Hyrtios erecta
Scalarane-type sesterterpene
Configuration
PTP1B
Guaiane-type Sesquiterpenoid Dimers from Artemisia zhongdianensis and Antihepatoma Carcinoma Activity via the p38MAPK Pathway
期刊论文
OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2023, 卷号: 41, 期号: 19, 页码: 2453-2468
作者:
Dong,Wei
;
Ma,Wen-Jing
;
Ma,Yun-Bao
;
Li,Feng-Jiao
;
Li,Tian-Ze
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/07/10
Artemzhongdianolides B1-B17
Artemisia zhongdianensis
Guaiane-type sesquiterpenoid dimers
Antihepatoma activity
p38MAPK pathway
Cancer
NMR spectroscopy
X-ray diffraction
ARREST
CELLS
JNK
Discovery and biological evaluation of a new type of dual inhibitors of indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase from ethnomedicinal plant Dactylicapnos scandens
期刊论文
OAI收割
PHYTOCHEMISTRY, 2023, 卷号: 214, 页码: 113794
作者:
Bao,Mei-Fen
;
Yang,Xin-Ni
;
Wu,Jing
;
Liu,Jiang-Xin
;
Cai,Xiang-Hai
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/07/25
Dactylicapnos scandens (D. don) hutch.
Isoquinoline alkaloids
Aporphine-type alkaloids
Dactycapnine a
IDO1/TDO dual inhibitor
APORPHINE ALKALOIDS
N-OXIDE
INFLAMMATION
PATHWAY
THALIPORPHINE
COMPLEXES
CANCER
ROOTS
Application of the Godunov-Type Corrective Smoothed Particle Method to Impulsive Load Studies
期刊论文
OAI收割
JOURNAL OF APPLIED FLUID MECHANICS, 2022, 卷号: 15, 期号: 6, 页码: 1889-1899
作者:
Zhang, M.
;
Zhang, J. M.
;
Zhang M
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/11/08
Meshfree method
SPH method
Godunov-type corrective smoothed particle method (GSPM)
1D shock tube
1D detonation wave
Metabolic-related gene pairs signature analysis identifies ABCA1 expression levels on tumor-associated macrophages as a prognostic biomarker in primary IDHWT glioblastoma
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2022, 卷号: 13
作者:
Wang, Shiqun
;
Li, Lu
;
Zuo, Shuguang
;
Kong, Lingkai
;
Wei, Jiwu
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/12/22
primary glioblastoma
wild-type isocitrate dehydrogenase
metabolic-related gene pairs
prognosis
tumor-associated macrophages
ABCA1
Coronarin A modulated hepatic glycogen synthesis and gluconeogenesis via inhibiting mTORC1/S6K1 signaling and ameliorated glucose homeostasis of diabetic mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 14
作者:
Huang, Su-Ling
;
Xie, Wei
;
Ye, Yang-Liang
;
Liu, Jia
;
Qu, Hui
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2022/11/11
type 2 diabetes mellitus
coronarin A
glycogen synthesis
gluconeogenesis
mTORC1
IRS1
Dimeric styrylpyrones with stimulating GLP-1 secretion activities from Alpinia kwangsiensis
期刊论文
OAI收割
TETRAHEDRON, 2022, 卷号: 120, 页码: 7
作者:
Wu, Meng-Zhen
;
GongPan, Pian-Chou
;
Dai, Meng -Yuan
;
Sun, Peng
;
Xiao, Chun-Fen
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2022/12/13
Glucagon-like peptide-1
Type 2 diabetes
Alpinia kwangsiensis
Dimeric styrylpyrones