中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [19]
过程工程研究所 [3]
金属研究所 [2]
合肥物质科学研究院 [2]
近代物理研究所 [2]
生物物理研究所 [1]
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OAI收割 [29]
内容类型
期刊论文 [29]
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2025 [1]
2024 [3]
2023 [3]
2022 [4]
2021 [6]
2020 [6]
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学科主题
Cell Biolo... [1]
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De Novo Design of Structure-Tunable Multivalent Targeting Chimeras for Tumor-Targeted PD-L1 Degradation and Potentiated Cancer Immunotherapy
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 17
作者:
Zhou, Huiling
;
Hou, Bo
;
Shan, Yiming
;
Huang, Lujia
;
Chen, Fangmin
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/23
Combinatory therapy, Immune checkpoint blockade, Multivalent targeting chimeras
Tumor microenvironment
Tumor-specific PD-L1 degradation
Dynamic polyphenol nanoparticles boost cuproptosis-driven metalloimmunotherapy of breast cancer
期刊论文
OAI收割
NANO TODAY, 2024, 卷号: 58, 页码: 12
作者:
Zhang, Huijuan
;
Chen, Fangmin
;
Cheng, Wenhao
;
Lai, Yi
;
Hou, Bo
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/10/09
Polyphenol
Cuproptosis
Dynamic covalent bond
Cancer metalloimmunotherapy
Tumor immune microenvironment
Small-molecule agents for cancer immunotherapy
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 3, 页码: 905-952
作者:
Wang, Fang
;
Fu, Kai
;
Wang, Yujue
;
Pan, Can
;
Wang, Xueping
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/10/21
Cancer immunotherapy
Small-molecule agents
Immune checkpoints
Oncogenic signaling
Metabolic pathways
Cytokine/chemokine signaling
Antitumor immunity
Tumor immune microenvironment
Activating CD8
+
T Cells by Pt(IV) Prodrug-Based Nanomedicine and aPD-L1 Antibody for Enhanced Cancer Immunotherapy
期刊论文
OAI收割
ADVANCED MATERIALS, 2024, 页码: 15
作者:
Wang, Bin
;
Zhou, Jingyu
;
Li, Ruitong
;
Tang, Dongsheng
;
Cao, Zheng
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2024/04/09
chemotherapy
immunotherapy
immunogenic cell death
tumor immune microenvironment
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably
Targeting lactate metabolism and immune interaction in breast tumor via protease-triggered delivery
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2023, 卷号: 358, 页码: 706-717
作者:
Zhao, Pengfei
;
Wang, Shuang
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2023/10/17
Legumain
Lactate
Tumor immune microenvironment (TIME)
Quercetin
Immunometabolism
Recombinant cell-penetrating trichosanthin synergizes anti-PD-1 therapy in colorectal tumor
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2023, 卷号: 19, 期号: 6, 页码: 1698-1712
作者:
Zhang, Meng
;
Liu, Ergang
;
Chen, Guihua
;
Tang, Yisi
;
Fang, Yuefei
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
Trichosanthin
cell -penetrating peptide
anti -PD-1 therapy
tumor immune microenvironment
colorectal cancer
Efficient Immunotherapy of Drug-Free Layered Double Hydroxide Nanoparticles via Neutralizing Excess Acid and Blocking Tumor Cell Autophagy
期刊论文
OAI收割
ACS NANO, 2022, 卷号: 16, 期号: 8, 页码: 12036-12048
作者:
Zhang, Lingxiao
;
Jia, Yingbo
;
Yang, Jinju
;
Zhang, Lun
;
Hou, Shengjie
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2023/02/24
layered double hydroxide nanoparticles
tumor immune microenvironment
acidosis
tumor cell apoptosis
cancer immunotherapy
Bispecific prodrug nanoparticles circumventing multiple immune resistance mechanisms for promoting cancer immunotherapy
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 6, 页码: 2695-2709
作者:
Ye, Jiayi
;
Hou, Bo
;
Chen, Fangmin
;
Zhang, Shunan
;
Xiong, Muya
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/03/21
Immunotherapy
Prodrug nanoparticles
Immune evasion
Immunogenic cell death
Tumor microenvironment
Anti-alcoholism drug disulfiram for targeting glioma energy metabolism using BBB-penetrating delivery of fixed-dose combination
期刊论文
OAI收割
NANO TODAY, 2022, 卷号: 44, 页码: 16
作者:
Zhao, Pengfei
;
Qu, Jingkun
;
Wu, Aihua
;
Wang, Shuang
;
Tang, Xueping
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2022/06/15
Fixed-dose codelivery
Glioma
Energy metabolism
Tumor immune microenvironment
Disulfiram
Shikonin
Immunogenic cell death
Tumor-associated macrophage