中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-
d
]pyrimidin-7(6
H
)-one" Scaffold for the Treatment of B Cell Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2884-2906
作者:
Liang, Xuewu
;
Yu, Haolan
;
Liang, Renwen
;
Feng, Zhuanghui
;
Saidahmatov, Abdusaid
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/04/09
Role of F-box proteins in human upper gastrointestinal tumors
期刊论文
OAI收割
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2024, 卷号: 1879, 期号: 1, 页码: 16
作者:
Zhang, Che
;
Pan, Guangzhao
;
Qin, Jiang-Jiang
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/02/27
F-box protein
Upper gastrointestinal cancer
E3 ubiquitin ligase
Ubiquitin
Berberine derivative DCZ0358 induce oxidative damage by ROS-mediated JNK signaling in DLBCL cells
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 卷号: 125, 页码: 15
作者:
Feng, Qilin
;
Hu, Ke
;
Hu, Huifang
;
Lu, Yumeng
;
Zhang, Hui
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/01/16
DLBCL
ROS
DNA damage
JNK
Mitochondrial dysfunction
Inhibiting Endothelial Cell-Mediated T Lymphocyte Apoptosis with Integrin-Targeting Peptide-Drug Conjugate Filaments for Chemoimmunotherapy of Triple-Negative Breast Cancer
期刊论文
OAI收割
ADVANCED MATERIALS, 2023, 页码: 12
作者:
Cai, Ying
;
Zhu, Binyu
;
Shan, Xiaoting
;
Zhou, Lingli
;
Sun, Xujie
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/01/16
Fas ligand
immunotherapy
peptide-drug conjugate
triple-negative breast cancer
tumor-associated endothelial cells
Biocompatible Ferrofluid-Based Millirobot for Tumor Photothermal Therapy in Near-Infrared-II Window
期刊论文
OAI收割
ADVANCED HEALTHCARE MATERIALS, 2023, 页码: 12
作者:
Ji, Yiming
;
Bai, Xue
;
Sun, Hongyan
;
Wang, Luyao
;
Gan, Chunyuan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/02/22
ferrofluid robots
biocompatibility
targeted therapy
TI17, a novel compound, exerts anti-MM activity by impairing Trip13 function of DSBs repair and enhancing DNA damage
期刊论文
OAI收割
CANCER MEDICINE, 2023, 页码: 14
作者:
Chang, Shuaikang
;
Xiao, Wenqin
;
Xie, Yongsheng
;
Xu, Zhijian
;
Li, Bo
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/11
DNA damage
DSBs repair
myeloma
TI17
Trip13
Deubiquitylating Enzymes in Cancer and Immunity
期刊论文
OAI收割
ADVANCED SCIENCE, 2023, 页码: 37
作者:
Ren, Jiang
;
Yu, Peng
;
Liu, Sijia
;
Li, Ran
;
Niu, Xin
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08
cancer
deubiquitylating enzymes (DUBs)
immunity
therapeutic approach
Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR & gamma; antagonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 15
作者:
Mei, Lianghe
;
Xu, Lansong
;
Wu, Sanan
;
Wang, Yafang
;
Xu, Chao
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2023/10/17
Betulinic acid
ROR & gamma
Target identification
Rationale structure optimization
Anti-tumor effects
antagonists
HIF-1 alpha inhibition in macrophages preserves acute liver failure by reducing IL-1 beta production
期刊论文
OAI收割
FASEB JOURNAL, 2023, 卷号: 37, 期号: 9, 页码: 12
作者:
Kong, Xiangrong
;
Liu, Wei
;
Zhang, Xinwen
;
Zhou, Chendong
;
Sun, Xinyu
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
acute liver failure
cell death
HIF-1 alpha inhibitor
interleukin-1 beta
macrophage
Novel thieno[2,3-b]quinoline-procaine hybrid molecules: A new class of allosteric SHP-1 activators evolved from PTP1B inhibitors
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2023, 卷号: 34, 期号: 8, 页码: 6
作者:
Xu, Lei
;
Xuyan, Xuyang
;
Minmi, Minmin
;
Wang, Zhiji
;
Shee, Chao
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2023/10/17
Activator
PTPs
Inhibitor
Thieno[2
b ]quinoline derivatives
Diffuse large B-cell lymphoma