中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [13]
金属研究所 [3]
中国科学院大学 [2]
长春应用化学研究所 [2]
上海神经科学研究所 [1]
采集方式
OAI收割 [19]
iSwitch采集 [2]
内容类型
期刊论文 [21]
发表日期
2016 [1]
2013 [5]
2012 [2]
2011 [1]
2010 [1]
2009 [2]
更多
学科主题
Neuroscien... [2]
筛选
浏览/检索结果:
共21条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
题名升序
题名降序
提交时间升序
提交时间降序
作者升序
作者降序
发表日期升序
发表日期降序
Platinum-coordinated graphitic carbon nitride nanosheet used for targeted inhibition of amyloid beta-peptide aggregation
期刊论文
iSwitch采集
Nano research, 2016, 卷号: 9, 期号: 8, 页码: 2411-2423
作者:
Li, Meng
;
Guan, Yijia
;
Chen, Zhaowei
;
Gao, Nan
;
Ren, Jinsong
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2019/05/09
Amyloid disease
Platinum
Graphitic carbon nitride nanosheet
Photooxygenation
Amyloid beta-peptide (a beta) inhibitors
Microsecond molecular dynamics simulation of A beta(42) and identification of a novel dual inhibitor of A beta(42) aggregation and BACE1 activity
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 9, 页码: 1243-1250
作者:
Wang, Yuan-yuan
;
Li, Li
;
Chen, Tian-tian
;
Chen, Wu-yan
;
Xu, Ye-chun
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
amyloid beta-peptide (A beta)
beta-secretase
Alzheimer's disease (AD)
dual inhibitor
structure-based virtual screening
molecular dynamics (MD) simulation
Cerium oxide caged metal chelator: anti-aggregation and anti-oxidation integrated H2O2-responsive controlled drug release for potential Alzheimer's disease treatment
期刊论文
OAI收割
chemical science, 2013, 卷号: 4, 期号: 6, 页码: 2536-2542
Li M
;
Shi P
;
Xu C
;
Ren JS
;
Qu XG
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2014/04/18
AMYLOID-BETA-PEPTIDE
RESPONSIVE CONTROLLED-RELEASE
A-BETA
NEURONAL SURVIVAL
OXIDATIVE STRESS
NANOPARTICLES
COPPER
AGGREGATION
BINDING
SCAFFOLDS
Gold Nanocage-Based Dual Responsive "Caged Metal Chelator" Release System: Noninvasive Remote Control with Near Infrared for Potential Treatment of Alzheimer's Disease
期刊论文
OAI收割
advanced functional materials, 2013, 卷号: 23, 期号: 43, 页码: 5412-5419
Shi P
;
Li M
;
Ren JS
;
Qu XG
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2014/04/15
AMYLOID-BETA-PEPTIDE
BLOOD-BRAIN-BARRIER
A-BETA
MESOPOROUS SILICA
DRUG-DELIVERY
CANCER-CELLS
HYDROGEN-PEROXIDE
PHOTOTHERMAL DESTRUCTION
OPTICAL-PROPERTIES
AGGREGATION
microsecondmoleculardynamicssimulationofa42andidentificationofanoveldualinhibitorofa42aggregationandbace1activity
期刊论文
OAI收割
actapharmacologicasinica, 2013, 卷号: 34, 期号: 9, 页码: 1243
作者:
Wang Yuanyuan
;
Li Li
;
Chen Tiantian
;
Chen Wuyan
;
Xu Yechun
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/07/01
amyloid β-peptide (Aβ)
β-secretase
Alzheimer’s disease (AD)
dual inhibitor
structure-based virtual screening
molecular dynamics (MD) simulation
Microsecond molecular dynamics simulation of Aβ_(42) and identification of a novel dual inhibitor of Aβ_(42) aggregation and BACE1 activity
期刊论文
OAI收割
Acta Pharmacologica Sinica, 2013, 卷号: 34, 期号: 9, 页码: 1243
作者:
Wang Yuanyuan
;
Li Li
;
Chen Tiantian
;
Chen Wuyan
;
Xu Yechun
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/12/24
amyloid β-peptide (Aβ)
β-secretase
Alzheimer’s disease (AD)
dual inhibitor
structure-based virtual screening
molecular dynamics (MD) simulation
Macromolecular and small-molecule modulation of intracellular A beta(42) aggregation and associated toxicity
期刊论文
OAI收割
BIOCHEMICAL JOURNAL, 2012, 卷号: 442, 页码: 507-515
作者:
Chakrabortee, Sohini
;
Liu, Yun
;
Zhang, Liao
;
Matthews, Helena R.
;
Zhang, Hanrui
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
amyloid beta-peptide (A,beta)
late embryogenesis abundant (LEA) protein
protein aggregation
polysaccharide
traditional Chinese medicine
Decreased Accumulation of Subcellular Amyloid-beta with Improved Mitochondrial Function Mediates the Neuroprotective Effect of Huperzine A
期刊论文
OAI收割
JOURNAL OF ALZHEIMERS DISEASE, 2012, 卷号: 31, 期号: 1, 页码: 131-142
作者:
Yang, Ling
;
Ye, Chun-yan
;
Huang, Xiao-tian
;
Tang, Xi-can
;
Zhang, Hai-yan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Alzheimer's disease
amyloid-beta peptide
huperzine A
mitochondrial dysfunction
oligomer
Induced Th2 dominant immune response in APPswe, PSEN1dE9 transgenic mice after nasal immunization with an adenoviral vector encoding 10 tandem repeats of beta-amyloid 3-10
期刊论文
OAI收割
NEURAL REGENERATION RESEARCH, 2011, 卷号: 6, 期号: 26, 页码: 2005-2012
作者:
Guo Rong
;
Huang Kui
;
Jiang Tongzi
;
Li Jian
;
Li Yu
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/02/26
ALZHEIMERS-DISEASE
MOUSE MODEL
FOLLOW-UP
PEPTIDE
NEUROPATHOLOGY
A-BETA-1-40/42
VACCINATION
IMMUNOGENS
PATHOLOGY
PROTEIN
Alzheimer's disease
immunotherapy
gene vaccine
amyloid plaque
T cell immunity response
neural regeneration
Regulation of beta cleavage of amyloid precursor protein
期刊论文
OAI收割
NEUROSCIENCE BULLETIN, 2010, 卷号: 26, 期号: 5, 页码: 417-427
Wang, Jun-Feng
;
Lu, Rui
;
Wang, Yi-Zheng
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2012/07/13
Alzheimer's disease
amyloid beta peptide
amyloid precursor protein
beta secretase
APP TRANSGENIC MICE
ALZHEIMERS-DISEASE
A-BETA
SECRETASE ACTIVITY
PLAQUE-FORMATION
GAMMA-SECRETASE
GENE-EXPRESSION
IN-VIVO
BACE1
BRAIN