中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [58]
昆明植物研究所 [12]
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Small Molecule SHP2 Inhibitor LXQ-217 affects Lung Cancer Cell Proliferation in Vitro and in Vivo
期刊论文
OAI收割
CHEMISTRY & BIODIVERSITY, 2024, 页码: 11
作者:
Sun, Hao
;
Bai, Xiaoyi
;
Zhang, Yiting
;
Gao, Yanan
;
Dai, Jiajia
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/06/04
Anti-tumor
SHP2
Orthosteric inhibitor
Apoptosis
Bromophenol
Opportunities and challenges of fucoidan for tumors therapy
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2024, 卷号: 324, 页码: 13
作者:
Yu, Haoyu
;
Zhang, Quanbin
;
Farooqi, Ammad Ahmad
;
Wang, Jing
;
Yue, Yang
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/04/07
Brown algae
Fucoidan
Structure
Anti-tumor
Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR & gamma; antagonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 15
作者:
Mei, Lianghe
;
Xu, Lansong
;
Wu, Sanan
;
Wang, Yafang
;
Xu, Chao
  |  
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2023/10/17
Betulinic acid
ROR & gamma
Target identification
Rationale structure optimization
Anti-tumor effects
antagonists
Recombinant cell-penetrating trichosanthin synergizes anti-PD-1 therapy in colorectal tumor
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2023, 卷号: 19, 期号: 6, 页码: 1698-1712
作者:
Zhang, Meng
;
Liu, Ergang
;
Chen, Guihua
;
Tang, Yisi
;
Fang, Yuefei
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/10/17
Trichosanthin
cell -penetrating peptide
anti -PD-1 therapy
tumor immune microenvironment
colorectal cancer
Biogenic platinum nanoparticles on bacterial fragments for enhanced radiotherapy to boost antitumor immunity
期刊论文
OAI收割
NANO TODAY, 2022, 卷号: 47, 页码: 10
作者:
Deng, Zheng
;
Liu, Jiawei
;
Xi, Min
;
Wang, Chunjie
;
Fang, Huapan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/29
Radiotherapy
Platinum nanoparticles
Shewanella oneidensis MR-1
Immune checkpoint blockade
Anti-tumor immunity
Microvesicle-inspired oxygen-delivering nanosystem potentiates radiotherapy-mediated modulation of tumor stroma and antitumor immunity
期刊论文
OAI收割
BIOMATERIALS, 2022, 卷号: 290, 页码: 19
作者:
Gong, Xiang
;
Li, Jie
;
Xu, Xiaoxuan
;
Wu, Yao
;
Lei, Ying
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/12/13
Microvesicle
Tumor hypoxia
Tumor stroma
Radiotherapy
Anti-tumor immune response
A Traceless Site-Specific Conjugation on Native Antibodies Enables Efficient One-Step Payload Assembly
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 页码: 11
作者:
Zeng, Yue
;
Shi, Wei
;
Dong, Qian
;
Li, Wanzhen
;
Zhang, Jianxin
  |  
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2022/08/30
Acyl Transfer
Anti-Tumor
One-Step Synthesis
Site-Specific ADCs
Thioester
Modeling the efficacy of different anti-angiogenic drugs on treatment of solid tumors using 3D computational modeling and machine learning
期刊论文
OAI收割
COMPUTERS IN BIOLOGY AND MEDICINE, 2022, 卷号: 146, 页码: 16
作者:
Mousavi, Milad
;
Manshadi, Mahsa Dehghan
;
Soltani, Madjid
;
Kashkooli, Farshad M.
;
Rahmim, Arman
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/09/21
Solid tumor
Tumor growth
Anti-angiogenic drugs
Bevacizumab
Ranibizumab
Brolucizumab
Artificial intelligence
Cancer
Noncanonical PD-1/PD-L1 Axis in Relation to the Efficacy of Anti-PD Therapy
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2022, 卷号: 13, 页码: 12
作者:
Long, Yiru
;
Yu, Xiaolu
;
Chen, Runqiu
;
Tong, Yongliang
;
Gong, Likun
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/08/16
noncanonical PD-1
PD-L1 axis
T-cells
tumor cells
myeloid cells
anti-PD therapy
Discovery of N-(3-bromo-1H-indol-5-yl)-quinazolin-4-amine as an effective molecular skeleton to develop reversible/irreversible pan-HER inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 233, 页码: 13
作者:
Tang, Qidong
;
Peng, Ting
;
Hu, Jie
;
Zhang, Tao
;
Chen, Pengqin
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2022/08/16
Reversible
irreversible pan-HER inhibitor
Quinazolin-4-amine derivatives
Anti-tumor
Structure-activity relationship