中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [9]
上海生物化学与细胞生... [5]
水生生物研究所 [4]
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OAI收割 [23]
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期刊论文 [22]
会议论文 [1]
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2024 [1]
2020 [1]
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2018 [3]
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2016 [2]
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Immunology [2]
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Targeting CCL2-CCR2 signaling pathway alleviates macrophage dysfunction in COPD via PI3K-AKT axis
期刊论文
OAI收割
CELL COMMUNICATION AND SIGNALING, 2024, 卷号: 22, 期号: 1, 页码: 19
作者:
Dong, Yue
;
Dong, Ying
;
Zhu, Chengyue
;
Yang, Lan
;
Wang, Hanlin
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/08/22
Chronic obstructive pulmonary disease
C-C motif chemokine ligand 2
C-C chemokine receptor type 2
Bronchial epithelial cells
Macrophage
Revealing the Positive Binding Cooperativity Mechanism between the Orthosteric and the Allosteric Antagonists of CCR2 by Metadynamics and Gaussian Accelerated Molecular Dynamics Simulations
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2020, 卷号: 11, 期号: 4, 页码: 628-637
作者:
An, Xiaoli
;
Bai, Qifeng
;
Bing, Zhitong
;
Liu, Hongli
;
Zhang, Qianqian
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/01/18
CC chemokine receptor 2
orthosteric antagonist
allosteric antagonist
binding cooperativity
metadynamics simulation
Gaussian accelerated MD simulation
CKLF1 Aggravates Focal Cerebral Ischemia Injury at Early Stage Partly by Modulating Microglia/Macrophage Toward M1 Polarization Through CCR4
期刊论文
OAI收割
CELLULAR AND MOLECULAR NEUROBIOLOGY, 2019, 卷号: 39, 期号: 5, 页码: 651, 669
作者:
Chen, C
;
Chu, SF
;
Ai, QD
;
Zhang, Z
;
Guan, FF
  |  
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2019/06/14
CKLF1
CHEMOKINE-LIKE FACTOR-1
CCR4
SEX-DIFFERENCES
Ischemic stroke
REPERFUSION INJURY
Microglia
RECEPTOR 5
macrophage
STROKE
Polarization
BRAIN
ACTIVATION
EXPRESSION
MICROGLIA
MECHANISM
The chemical diversity and structure-based evolution of non-peptide CXCR4 antagonists with diverse therapeutic potential
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 149, 页码: 148-169
作者:
Peng, Dian
;
Cao, Bin
;
Zhou, Ying-Jun
;
Long, Ya-Qiu
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/01/08
CXC chemokine receptor 4
Small molecule antagonists
Structure-based optimization
HIV-1 entry
Tumor metastasis
Inflammation
Ischemia-reperfusion
Autoimmune
CXCR7 regulates breast tumor metastasis and angiogenesis in vivo and in vitro
期刊论文
OAI收割
MOLECULAR MEDICINE REPORTS, 2018, 卷号: 17, 期号: 3, 页码: 3633-3639
作者:
Qian, TT
;
Liu, YC
;
Dong, Y
;
Zhang, L
;
Dong, YN
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2018/09/06
Hepatocellular-carcinoma Cells
Chemokine Receptor Cxcr7
Mesenchymal Stem-cells
Prostate-cancer
Growth
Expression
Lung
Prognosis
Migration
Proliferation
Extracellular matrix protein 1 promotes follicular helper T cell differentiation and antibody production
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 卷号: 115, 期号: 34, 页码: 8621-8626
作者:
He, Lan
;
Gu, Wangpeng
;
Zhang, Yuan
;
Yan, Chenghua
;
Su, Pan
  |  
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2019/04/28
Cxc Chemokine Receptor-5
Icos
Bcl6
Induction
Responses
Stat5
Pd-1
Fh
Molecular characterization and expression analysis of four fish-specific CC chemokine receptors CCR4La, CCR4Lc1, CCR4Lc2 and CCR11 in rainbow trout (Oncorhynchus mykiss)
会议论文
OAI收割
Santiago de Compostela, SPAIN, JUN 21-27, 2015
作者:
Qi, Zhitao
;
Holland, Jason W.
;
Jiang, Yousheng
;
Secombes, Christopher J.
;
Nie, Pin
  |  
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2019/08/01
Rainbow trout
CC chemokine receptor
CCR4La
CCR4Lc
CCR11
Expression
Modulation
Pro-inflammatory cytokine
Bacterial infection
Parasitic infection
CXCR4 ACTIVATION PROMOTES DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS TO NEURAL STEM CELLS
期刊论文
OAI收割
NEUROSCIENCE, 2016, 卷号: 337, 页码: 88-97
作者:
Zhang, Lijun
;
Hua, Qiuhong
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/01/08
human embryonic stem cell
neural stem/precursor cell
neural differentiation
chemokine receptor
CXCR4
SDF-1
Structural Studies of G Protein-Coupled Receptors
期刊论文
OAI收割
IUBMB LIFE, 2016, 卷号: 68, 期号: 11, 页码: 894-903
作者:
Lu, Mengjie
;
Wu, Beili
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
G protein-coupled receptor
structural studies
chemokine receptor
purinergic receptor
Pharmacophore Model-based Design and Synthesis of New Structure Small Molecule CCR2 Inhibitors
期刊论文
OAI收割
ACTA CHIMICA SINICA, 2015, 卷号: 73, 期号: 7, 页码: 679-684
作者:
Qin Lihuai
;
Li Xiaoguang
;
Wang Zhilong
;
Yao Wenbo
;
Wang Hui
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/01/08
chemokine receptor CCR2
small molecule antagonist
pharmacophore
N-(3-aminocyclopentanecarbox-amido)methyl)benzamide