机构

• 上海药物研究所 [5]
• 上海营养与健康研究所 [2]
• 海洋研究所 [1]

采集方式

• OAI收割 [8]

内容类型

• 期刊论文 [8]

发表日期

• 2019 [1]
• 2017 [1]
• 2014 [3]
• 2013 [1]
• 2010 [2]

学科主题

筛选

浏览/检索结果: 共8条，第1-8条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Toward a treatment of diabesity: In vitro and in vivo evaluation of uncharged bromophenol derivatives as a new series of PTP1B inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 166, 页码: 178-185 作者:  Li, Xiangqian;  Xu, Qi;  Li, Chao;  Luo, Jiao;  Li, Xiuxue   |  收藏  |  浏览/下载：64/0  |  提交时间：2019/05/15 Anti-diabetic  PTP1B inhibitor  Selectivity  BKS db mice  Toxicity   Design, synthesis and. biological evaluation of 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines as novel adenosine 5 '-monophosphate-activated protein kinase (AMPK) indirect activators for the treatment of type 2 diabetes 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 448-464 作者:  Zhou, Shengbin;  Duan, Yanan;  Wang, Jiang;  Zhang, Jin;  Sun, Haifeng   |  收藏  |  浏览/下载：37/0  |  提交时间：2019/01/08 Tetrahydroberberine  4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines  Mitochondrial respiration  AMPK indirect activators  db/db mice   Hepatic serum- and glucocorticoid-regulated protein kinase 1 (SGK1) regulates insulin sensitivity in mice via extracellular-signal-regulated kinase 1/2 (ERK1/2) 期刊论文  OAI收割 BIOCHEMICAL JOURNAL, 2014, 卷号: 464, 期号: 2, 页码: 281-289 作者:  Liu, Hao;  Yu, Junjie;  Xia, Tingting;  Xiao, Yuzhong;  Zhang, Qian 收藏  |  浏览/下载：14/0  |  提交时间：2016/01/15 db/db mice  extracellular-signal-regulated kinase 1/2 (ERK 1/2)  glucose  hepatocyte  insulin signalling  liver  serum-and glucocorticoid-regulated kinase 1 (SGK 1)   Central prolactin receptors (PRLRs) regulate hepatic insulin sensitivity in mice via signal transducer and activator of transcription 5 (STAT5) and the vagus nerve 期刊论文  OAI收割 DIABETOLOGIA, 2014, 卷号: 57, 期号: 10, 页码: 2136-2144 作者:  Xiao, Fei;  Xia, Tingting;  Lv, Ziquan;  Zhang, Qian;  Xiao, Yuzhong 收藏  |  浏览/下载：16/0  |  提交时间：2016/01/15 Central nervous system  db/db mice  Diabetes  Hypothalamus  Insulin sensitivity  Peripheral tissues  Prolactin receptor  STAT5  Vagus nerve   Hypoglycemic activity of polyphenol-rich extract from Cinnamomun japonicum Sieb 期刊论文  OAI收割 Chinese Traditional Patent Medicine, 2014, 卷号: 36, 期号: 2, 页码: 229-235 作者:  Chen Liang;  Sun Peng;  Wang Ting;  Xu Na;  Jia Qi   |  收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 Cinnamomun japonicum Sieb.  polyphenol  pancreatic INS-1 beta cells  type 2 diabetic db /db mice  anti-diabetic activity   Marine natural product des-O-methyllasiodiplodin effectively lowers the blood glucose level in db/db mice via ameliorating inflammation 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 10, 页码: 1325-1336 作者:  Zhou, Rong;  Lin, Zhong-hui;  Jiang, Cheng-shi;  Gong, Jing-xu;  Chen, Li-li   |  收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08 des-O-methyllasiodiplodin  diabetes  db/db mice  pro-inflammatory cytokine  ROS  mineralocorticoid receptor  aldosterone  blood glucose  glycosylated hemoglobin (HbA1c)   Pharmacological inhibition of diacylglycerol acyltransferase 1 reduces body weight gain, hyperlipidemia, and hepatic steatosis in db/db mice 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2010, 卷号: 31, 期号: 11, 页码: 1470-1477 作者:  Zhang, Xiao-dong;  Yan, Jian-wei;  Yan, Gui-rui;  Sun, Xiao-yun;  Ji, Jun   |  收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08 diabetes  hepatic steatosis  obesity  hyperlipidemia  small-molecule inhibitor  H128  diacylglycerol acyltransferase 1  db/db mice  CPT1 gene  PPAR alpha gene   8,8-Dimethyldihydroberberine with improved bioavailability and oral efficacy on obese and diabetic mouse models 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2010, 卷号: 18, 期号: 16, 页码: 5915-5924 作者:  Cheng, Zhe;  Chen, An-Feng;  Wu, Fang;  Sheng, Li;  Zhang, Han-Kun   |  收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08 Berberine  Dihydroberberine  Di-Me  AMPK  Diet-induced obese mice  db/db mice