机构

• 上海药物研究所 [8]

采集方式

• OAI收割 [8]

内容类型

• 期刊论文 [8]

发表日期

• 2023 [2]
• 2019 [1]
• 2016 [1]
• 2015 [1]
• 2014 [2]
• 2011 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共8条，第1-8条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 A patent review of PRMT5 inhibitors to treat cancer (2018-present) 期刊论文  OAI收割 EXPERT OPINION ON THERAPEUTIC PATENTS, 2023, 页码: 28 作者:  Gao, Jing;  Yang, Jie;  Xue, Shengyu;  Ding, Hong;  Lin, Hua   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/10/17 PRMT5  inhibitor  epigenetic target  cancer treatment  combined treatment   Structure-activity relationship study of a series of nucleoside derivatives bearing sulfonamide scaffold as potent and selective PRMT5 inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 20 作者:  Chen, Yuting;  Shi, Qiongyu;  Yang, Hong;  Li, Jiayi;  Zhou, Kaixin   |  收藏  |  浏览/下载：35/0  |  提交时间：2023/04/10 Epigenetic  PRMT5 inhibitor  Nucleoside derivatives  Structure-activity Relationship Prodrug   Discovery of Novel PRMT5 Inhibitors by Virtual Screening and Biological Evaluations 期刊论文  OAI收割 CHEMICAL & PHARMACEUTICAL BULLETIN, 2019, 卷号: 67, 期号: 4, 页码: 382-388 作者:  Tao, Hongrui;  Yan, Xue;  Zhu, Kongkai;  Zhang, Hua   |  收藏  |  浏览/下载：21/0  |  提交时间：2020/07/01 virtual screening  epigenetic inhibitor  antiproliferation  molecular docking   DNA methyltransferase inhibitors: an updated patent review (2012-2015) 期刊论文  OAI收割 EXPERT OPINION ON THERAPEUTIC PATENTS, 2016, 卷号: 26, 期号: 9, 页码: 1017-1030 作者:  Xu, Pan;  Hu, Guang;  Luo, Cheng;  Liang, Zhongjie   |  收藏  |  浏览/下载：46/0  |  提交时间：2019/01/08 DNMT inhibitors (DNMTi)  epigenetic therapy  nucleotide derivatives  drug combination  allosteric inhibitor   Interaction Between DNA/histone Methyltransferases and their Inhibitors 期刊论文  OAI收割 CURRENT MEDICINAL CHEMISTRY, 2015, 卷号: 22, 期号: 3, 页码: 360-372 作者:  Hu, J.;  Chen, S.;  Kong, X.;  Zhu, K.;  Cheng, S.   |  收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08 DNA methyltransferase  drug discovery  epigenetic therapy  histone methyltransferase  inhibitor   EZH2: biology, disease, and structure-based drug discovery 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 2, 页码: 161-174 作者:  Tan, Jin-zhi;  Yan, Yan;  Wang, Xiao-xi;  Jiang, Yi;  Xu, H. Eric   |  收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 EZH2  PRC2  transcriptional repression  gene activation  anticancer drug  crystal structure  SET domain  methyltransferase inhibitor  epigenetic therapy   ezh2biologydiseaseandstructurebaseddrugdiscovery 期刊论文  OAI收割 actapharmacologicasinica, 2014, 卷号: 35, 期号: 2, 页码: 161 作者:  Tan Jinzhi;  Yan Yan;  Wang Xiaoxi;  Jiang Yi;  Xu H Eric   |  收藏  |  浏览/下载：21/0  |  提交时间：2020/07/01 EZH2  PRC2  transcriptional repression  gene activation  anticancer drug  crystal structure  SET domain  methyltransferase inhibitor  epigenetic therapy   Histone deacetylase inhibitor activity in royal jelly might facilitate caste switching in bees 期刊论文  OAI收割 EMBO REPORTS, 2011, 卷号: 12, 期号: 3, 页码: 238-243 作者:  Spannhoff, Astrid;  Kim, Yong Kee;  Raynal, Noel J. -M.;  Gharibyan, Vazganush;  Su, Ming-Bo   |  收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 Apis mellifera  epigenetic  HDAC inhibitor  phenotypic plasticity  royal jelly