机构

• 海洋研究所 [9]
• 上海药物研究所 [4]
• 南海海洋研究所 [3]
• 水生生物研究所 [3]
• 昆明植物研究所 [2]
• 过程工程研究所 [2]
• 更多

采集方式

• OAI收割 [28]

内容类型

• 期刊论文 [27]
• CNKI期刊论文 [1]

发表日期

• 2025 [1]
• 2022 [2]
• 2021 [5]
• 2020 [1]
• 2019 [3]
• 2018 [1]
• 更多

学科主题

• Immunology [4]
• Biochemist... [2]
• Fisheries [2]
• Limnology [2]
• Marine & F... [2]
• Oceanograp... [2]
• 更多

筛选

浏览/检索结果: 共28条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Design, synthesis and pharmacological evaluation of 1,2,3,4-tetrahydrobenzofuro[2,3-c] pyridine derivatives as p21-activated kinase 4 inhibitors for treatment of pancreatic cancer 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 1, 页码: 438-466 作者:  Li, Yang;  Fang, Yan;  Chen, Xiaoyu;  Tong, Linjiang;  Feng, Fang   |  收藏  |  浏览/下载：10/0  |  提交时间：2025/04/01 P21-activated kinase 4  Tetrahydrobenzofuro[2  3-c]pyridine  Structure-activity relationship  Allosteric inhibitor  Pharmacokinetics properties  Kinase selectivity  Pancreatic cancer  Immune infiltration   Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as novel and potent TBK1 inhibitors: design, synthesis, biological evaluation, and molecular docking study 期刊论文  OAI收割 JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1411-1425 作者:     |  收藏  |  浏览/下载：55/0  |  提交时间：2022/08/16 TBK1 inhibitors  1H-pyrazolo[3  4-b]pyridine  structure-activity relationships (SARs)  immune response  cancer therapy   Relationship Between the Structure and Immune Activity of Components From the Active Polysaccharides APS-II of Astragali Radix by Enzymolysis of Endo alpha-1,4-Glucanase 期刊论文  OAI收割 FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 15 作者:  Li, Ke;  Li, Xue-qin;  Li, Guang-xin;  Cui, Lian-jie;  Qin, Xue-mei   |  收藏  |  浏览/下载：34/0  |  提交时间：2022/06/15 APS-II  enzymolysis  structure analysis  immune activity  structure-activity relationship   Structural characteristics and immune-enhancing activity of an extracellular polysaccharide produced by marine Halomonas sp. 2E1 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 卷号: 183, 页码: 1660-1668 作者:  Wang, QingChi;  Wei, Maosheng;  Zhang, Jingjing;  Yue, Yang;  Wu, Ning   |  收藏  |  浏览/下载：44/0  |  提交时间：2021/08/17 Halomonas sp  Extracellular polysaccharide  Structure  Immune-enhancing activity  Macrophages   DAGM: A novel modelling framework to assess the risk of HER2-negative breast cancer based on germline rare coding mutations 期刊论文  OAI收割 EBIOMEDICINE, 2021, 卷号: 69, 页码: 11 作者:  Yang, Mei;  Fan, Yanhui;  Wu, Zhi-Yong   |  收藏  |  浏览/下载：85/0  |  提交时间：2021/12/01 HER2-negative breast cancer  Germline rare coding mutations  Damage assessment of genomic mutations (DAGM)  Risk assessment  Activity profiles of signalling pathways (APSP)  HER2 signalling pathway  Immune suppression   A specific and bioactive polysaccharide marker for Cordyceps 期刊论文  OAI收割 CARBOHYDRATE POLYMERS, 2021, 卷号: 269, 页码: 118343 作者:  Li,Li-Feng;  But,Grace Wing-Chiu;  Zhang,Quan-Wei;  Liu,Man;  Chen,Miao-Miao   |  收藏  |  浏览/下载：93/0  |  提交时间：2022/04/02 Cordyceps  Polysaccharide  Marker  Authentication  Immune activity  STRUCTURAL-ANALYSIS  SINENSIS  AUTHENTICATION  MACROPHAGES  SEQUENCE   Cordyceps polysaccharide marker CCP modulates immune responses via highly selective TLR4/MyD88/p38 axis 期刊论文  OAI收割 CARBOHYDRATE POLYMERS, 2021, 卷号: 271, 页码: 118443 作者:  Zhang,Quanwei;  Liu,Man;  Li,Lifeng;  Chen,Miaomiao;  Puno,Pema Tenzin   |  收藏  |  浏览/下载：88/0  |  提交时间：2022/04/02 Cordyceps  Polysaccharide  TLR4  MyD88  p38  Immune responses  Macrophage  NF-KAPPA-B  STRUCTURAL-CHARACTERIZATION  ANTIOXIDANT ACTIVITY  MYCELIAL FERMENTATION  SIGNALING PATHWAYS  FRUITING BODIES  SINENSIS FUNGUS  GENE-EXPRESSION  LIPOPOLYSACCHARIDE  RECOGNITION   黄芪活性多糖APS-II的酸降解及其降解寡糖的结构和免疫活性研究 期刊论文  OAI收割 药学学报, 2021, 卷号: 56, 期号: 8, 页码: 2266 作者:  石丽霞;  李科;  焦思明;  崔连杰;  秦雪梅   |  收藏  |  浏览/下载：0/0  |  提交时间：2023/05/22 APS-Ⅱ  partial acid hydrolysis  mass spectrometry analysis  separate preparation  immune activity evaluation  APS-Ⅱ  部分酸水解  质谱解析  分离制备  免疫活性评价   A Designed alpha-GalCer Analog Promotes Considerable Th1 Cytokine Response by Activating the CD1d-iNKT Axis and CD11b-Positive Monocytes/Macrophages 期刊论文  OAI收割 ADVANCED SCIENCE, 2020, 卷号: 7, 期号: 14, 页码: 1-9 作者:  Ma, Juan;  He, Peng;  Zhao, Chuanfang;  Ren, Quanzhong;  Dong, Zheng   |  收藏  |  浏览/下载：34/0  |  提交时间：2021/09/14 antitumor activity  CD11b monocytes  CD1d  Th1-biased immune responses  alpha-GalCer analogs   Identification and molecular characterization of peroxiredoxin 2 in grass carp (Ctenopharyngodon idella) 期刊论文  OAI收割 FISH & SHELLFISH IMMUNOLOGY, 2019, 卷号: 92, 期号: 1, 页码: 570-582 作者:  Zhu, Denghui;  Huang, Rong;  Yang, Cheng;  Fu, Peipei;  Chen, Liangming   |  收藏  |  浏览/下载：198/0  |  提交时间：2019/10/21 Grass carp  Recombinant protein  Peroxiredoxin 2 (Prx2)  Subcellular localization  Gene expression  Antioxidant activity  Immune response