机构

• 上海药物研究所 [18]
• 金属研究所 [2]
• 大连化学物理研究所 [1]
• 近代物理研究所 [1]

采集方式

• OAI收割 [22]

内容类型

• 期刊论文 [22]

发表日期

• 2023 [1]
• 2022 [1]
• 2021 [2]
• 2019 [2]
• 2017 [1]
• 2016 [3]
• 更多

学科主题

筛选

浏览/检索结果: 共22条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Prelimbic cortex dynorphin/& kappa; opioid receptor system modulates methamphetamine-induced cognitive impairment 期刊论文  OAI收割 ADDICTION BIOLOGY, 2023, 卷号: 28, 期号: 9, 页码: 12 作者:  Cheng, Ying-jie;  Deng, Ying-zhi;  Deng, Di;  Wu, Man-qing;  Chai, Jing-rui   |  收藏  |  浏览/下载：29/0  |  提交时间：2023/10/17 cognitive impairment  dynorphin  methamphetamine  prelimbic cortex  & kappa  opioid receptor   Upregulation of dynorphin/kappa opioid receptor system in the dorsal hippocampus contributes to morphine withdrawal-induced place aversion 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 8 作者:  Chen, Yan;  Wang, Chen-yao;  Zan, Gui-ying;  Yao, Song-yu;  Deng, Ying-zhi   |  收藏  |  浏览/下载：30/0  |  提交时间：2022/11/11 morphine withdrawal  conditioned place aversion  kappa opioid receptor  p38 MAPK  norBNI  dorsal hippocampus   Novel selective kappa agonists SLL-039 and SLL-1206 produce potent antinociception with fewer sedation and aversion 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Wei, Yuan-yuan;  Ma, Yan;  Yao, Song-yu;  Kong, Ling-hui;  Liu, Xiao   |  收藏  |  浏览/下载：46/0  |  提交时间：2021/11/04 kappa-opioid receptor agonist  4,5-expoxymorphinan  antinociception  conditioned place aversion  sedation  U50,488H  morphine  Nor-BNI  beta-FNA   Exploration of the SAR Connection between Morphinan- and Arylacetamide-Based kappa Opioid Receptor (kappa OR) Agonists Using the Strategy of Bridging 期刊论文  OAI收割 ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 6, 页码: 1018-1030 作者:  Liu, Xiao;  Jiang, Shuang;  Kong, Linghui;  Ye, Rongrong;  Xiao, Li   |  收藏  |  浏览/下载：99/0  |  提交时间：2021/05/24 Morphinans  arylacetamidyl substituent  kappa opioid receptor modulators  structure-activity relationships   Uncovering kappa-opioid receptor agonist-induced PAK1/2 phosphorylation by quantitative phosphoproteomics 期刊论文  OAI收割 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 516, 期号: 1, 页码: 320-326 作者:  Wu, Jianhong;  Jiang, Qinghui;  Zhu, Hongwen;  Zhou, Yanting;  Lu, Dayun   |  收藏  |  浏览/下载：38/0  |  提交时间：2020/07/01 Dimethyl labeling  Kappa-opioid receptor  Kinase-substrate network  p21-activated kinases  Quantitative phosphoproteomics   How Does Agonist and Antagonist Binding Lead to Different Conformational Ensemble Equilibria of the kappa-Opioid Receptor: Insight from Long-Time Gaussian Accelerated Molecular Dynamics Simulation 期刊论文  OAI收割 ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 3, 页码: 1575-1584 作者:  An, Xiaoli;  Bai, Qifeng;  Bing, Zhitong;  Zhou, Shuangyan;  Shi, Danfeng   |  收藏  |  浏览/下载：68/0  |  提交时间：2019/11/10 kappa-opioid receptor  Gaussian accelerated molecular dynamics simulation  agonist  antagonist  conformational change   The Pharmacological Heterogeneity of Nepenthone Analogs in Conferring Highly Selective and Potent kappa-Opioid Agonistic Activities 期刊论文  OAI收割 ACS CHEMICAL NEUROSCIENCE, 2017, 卷号: 8, 期号: 4, 页码: 766-776 作者:  Li, Wei;  Long, Jian-Dong;  Qian, Yuan-Yuan;  Long, Yu;  Xu, Xue-Jun   |  收藏  |  浏览/下载：47/0  |  提交时间：2019/01/08 kappa-opioid receptor  mu-opioid receptor  nepenthones  4,5-epoxymorphinans  pharmacological heterogeneity  structure activity relationship  binding structure   kappa Opioid receptor activation in different brain regions differentially modulates anxiety-related behaviors in mice 期刊论文  OAI收割 NEUROPHARMACOLOGY, 2016, 卷号: 110, 页码: 92-101 作者:  Wang, Yu-Jun;  Hang, Ai;  Lu, Yu-Chen;  Long, Yu;  Zan, Gui-Ying   |  收藏  |  浏览/下载：49/0  |  提交时间：2019/01/08 kappa Opioid receptor  pERK1/2  Region-specific  Dual effects  Anxiety   Design, synthesis and biological evaluation of novel tetrahydroisoquinoline quaternary derivatives as peripheral kappa-opioid receptor agonists 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 13, 页码: 2964-2970 作者:  Guo, Ting;  Gan, Zongjie;  Chen, Jie;  Wang, Dechuan;  He, Ling   |  收藏  |  浏览/下载：37/0  |  提交时间：2019/01/08 Tetrahydroisoquinoline quaternary derivatives  Peripheral  kappa-Opioid receptor agonists   p38 MITOGEN-ACTIVATED PROTEIN KINASE ACTIVATION IN AMYGDALA MEDIATES kappa OPIOID RECEPTOR AGONIST U50,488H-INDUCED CONDITIONED PLACE AVERSION 期刊论文  OAI收割 NEUROSCIENCE, 2016, 卷号: 320, 页码: 122-128 作者:  Zan, G. -Y.;  Wang, Q.;  Wang, Y. -J.;  Chen, J. -C.;  Wu, X.   |  收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 kappa opioid receptor  U50  488H  conditioned place aversion  p38 MAPK