中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
金属研究所 [1]
武汉植物园 [1]
合肥物质科学研究院 [1]
采集方式
OAI收割 [11]
内容类型
期刊论文 [10]
会议论文 [1]
发表日期
2025 [1]
2022 [2]
2021 [3]
2018 [1]
2016 [1]
2015 [1]
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学科主题
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Concurrent inhibition of p300/CBP and FLT3 enhances cytotoxicity and overcomes resistance in acute myeloid leukemia
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 14
作者:
Chen, Yu-jun
;
Zhao, Yu
;
Yao, Ming-yue
;
Wang, Ya-fang
;
Ma, Ming
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
acute myeloid leukemia
FLT3
p300/CBP
quizartinib resistance
combination strategy
Discovery of novel benzimidazole derivatives as potent p300 bromodomain inhibitors with anti-proliferative activity in multiple cancer cells
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 66, 页码: 16
作者:
Chen, Zonglong
;
Li, Jiayi
;
Yang, Hong
;
He, Yulong
;
Shi, Qiongyu
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2022/08/16
P300
Bromodomain inhibitors
CBP30
SBDD
Design, synthesis and biological evaluation of (R)-5-methylpyrrolidin-2-ones as p300 bromodomain inhibitors with Anti-Tumor activities in multiple tumor lines
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2022, 卷号: 124, 页码: 15
作者:
Liu, Ruiqi
;
Yang, Hong
;
Chen, Zonglong
;
Zhou, Kaixin
;
Shi, Qiongyu
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2022/08/16
Epigenetics
p300
CBP
Bromodomain inhibitors
CCS1477
Design, synthesis and biological evaluation of a novel spiro oxazolidinedione as potent p300/CBP HAT inhibitor for the treatment of ovarian cancer
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 52, 页码: 12
作者:
Ding, Hong
;
Pei, Yuan
;
Li, Yuanqing
;
Xu, Wen
;
Mei, Lianghe
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2022/06/15
Epigenetics
Histone acetyltransferase
P300/CBP
Ovarian cancer
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhou, Xiao-ru
;
Li, Xiao
;
Liao, Li-ping
;
Han, Jie
;
Huang, Jing
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2021/06/11
mantle cell lymphoma
idelalisib
drug resistance
P300
CBP
synergistic drug action
PI3Kδ
epigenetics
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhou, Xiao-ru
;
Li, Xiao
;
Liao, Li-ping
;
Han, Jie
;
Huang, Jing
  |  
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2021/06/11
mantle cell lymphoma
idelalisib
drug resistance
P300
CBP
synergistic drug action
PI3Kδ
epigenetics
Discovery and biological evaluation of thiobarbituric derivatives as potent p300/CBP inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 20, 页码: 5397-5407
作者:
Lu, Wenchao
;
Xiong, Huan
;
Chen, Yu
;
Wang, Chen
;
Zhang, Hao
  |  
收藏
  |  
浏览/下载:145/0
  |  
提交时间:2019/01/08
Drug discovery
Epigenetics
Histone acetyltransferase
P300/CBP
CBP-dependent Wnt/beta-catenin Signaling is Crucial in Regulation of MDR1 Transcription
期刊论文
OAI收割
CURRENT CANCER DRUG TARGETS, 2015, 卷号: 15, 期号: 6, 页码: 519-532
作者:
Xia, Zanxian
;
Guo, Mingquan
;
Liu, Han
;
Jiang, Luwei
;
Li, Qiaoxia
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2017/04/13
CBP
Chromatin Immunoprecipitation
MDR1
p300
RNAi
Wnt/beta-catenin
组蛋白乙酰化酶P300/CBP催化反应机理的理论计算研究
会议论文
OAI收割
作者:
欧阳斯盛
;
梁中洁
;
孔祥谦
;
卢俊彦
;
罗成
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
P300/CBP
分子动力学
QM/MM