中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
化学研究所 [4]
过程工程研究所 [3]
深圳先进技术研究院 [1]
宁波材料技术与工程研... [1]
昆明植物研究所 [1]
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OAI收割 [21]
iSwitch采集 [1]
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期刊论文 [21]
学位论文 [1]
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2023 [1]
2022 [2]
2021 [3]
2020 [2]
2019 [2]
2017 [2]
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Chemistry [1]
Chemistry;... [1]
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Combined inhibition of PARP and ATR synergistically potentiates the antitumor activity of HER2-targeting antibody-drug conjugate in HER2-positive cancers
期刊论文
OAI收割
AMERICAN JOURNAL OF CANCER RESEARCH, 2023, 卷号: 13, 期号: 1, 页码: 161-+
作者:
Li, Yongpeng
;
Li, Lin
;
Fu, Haoyu
;
Yao, Qing
;
Wang, Lei
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Antibody-drug conjugate
DS-8201
PARP
ATR
synergy
DNA damage
Self-assembled Pt(II) metallacycles enable precise cancer combination chemotherapy
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 卷号: 119
作者:
Zhang, Pengge
;
Zhou, Zhixuan
;
Long, Wen
;
Yan, Yuping
;
Li, Youshan
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/12/22
self-assembly
supramolecular coordination complex
combination chemotherapy
targeted cancer therapy
drug delivery
Intranasal Administration of Self-Oriented Nanocarriers Based on Therapeutic Exosomes for Synergistic Treatment of Parkinson's Disease
期刊论文
OAI收割
ACS NANO, 2022, 页码: 16
作者:
Peng, Huan
;
Li, Yan
;
Ji, Weihong
;
Zhao, Ruichen
;
Lu, Zhiguo
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/06/15
Parkinson's disease
MSC-derived exosomes
self-oriented nanocarrier
multiple membrane barriers
intranasal administration
three-pronged synergistic treatment
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
  |  
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhou, Xiao-ru
;
Li, Xiao
;
Liao, Li-ping
;
Han, Jie
;
Huang, Jing
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/06/11
mantle cell lymphoma
idelalisib
drug resistance
P300
CBP
synergistic drug action
PI3Kδ
epigenetics
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhou, Xiao-ru
;
Li, Xiao
;
Liao, Li-ping
;
Han, Jie
;
Huang, Jing
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2021/06/11
mantle cell lymphoma
idelalisib
drug resistance
P300
CBP
synergistic drug action
PI3Kδ
epigenetics
帕金森病靶向输递体系用于基因-化药协同治疗的研究
学位论文
OAI收割
: 中国科学院大学, 2020
作者:
刘霖颖
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/09/07
帕金森病,Sirna,联合递送,仿生设计
Enhancing cellular morphological changes and ablation of cancer cells via the interaction of drug co-loaded magnetic nanosystems in weak rotating magnetic fields
期刊论文
OAI收割
RSC ADVANCES, 2020, 卷号: 10, 期号: 25, 页码: 14471-14481
作者:
Wu, Tingting
;
Zhang, Qian
;
Hu, Huiping
;
Yang, Fang
;
Li, Ke
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/16
NANOPARTICLES
TETRANDRINE
INHIBITION
RESISTANCE
APOPTOSIS
PATHWAYS
RELEASE
IRON
Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762
期刊论文
OAI收割
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:
Wang, Jing-Nan
;
Che, Yun
;
Yuan, Zu-Yang
;
Lu, Zhi-Liang
;
Li, Yuan
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2019/03/18
Acetyl-macrocalin B
Reactive oxygen species
p38 MAPK
Chk1/Chk2
Esophageal squamous cell carcinoma
Intestinal Transporter-Associated Drug Absorption and Toxicity
期刊论文
OAI收割
DRUG TRANSPORTERS IN DRUG DISPOSITION, EFFECTS AND TOXICITY, 2019, 卷号: 1141, 页码: 361-405
作者:
Xue, Yaru
;
Ma, Chenhui
;
Hanna, Imad
;
Pan, Guoyu
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
Intestinal transporter
Drug absorption
Bile acid transport
BDDCS
Drug-induced toxicity