中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
武汉病毒研究所 [1]
近代物理研究所 [1]
采集方式
OAI收割 [8]
iSwitch采集 [1]
内容类型
期刊论文 [9]
发表日期
2024 [2]
2021 [1]
2016 [1]
2010 [1]
2009 [1]
2008 [1]
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学科主题
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The antidepressant-like effect and proposed mechanism of action of TPN672MA, a novel serotonin-dopamine receptor modulator for the treatment of schizophrenia
期刊论文
OAI收割
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2024, 卷号: 242, 页码: 13
作者:
Cheng, Jiaxin
;
Wu, Chunhui
;
Wang, Yu
;
Wang, Zhen
;
He, Yang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/09/24
TPN672MA
5-HT 1A receptor agonist
D 2 /D 3 receptor partial agonist
5-HT 2A receptor antagonist
Antidepressant-like
Mechanism
Design, Synthesis and Bioactivity of NYX-2925
L
-Proline Derivatives as
N
-Methyl-D-aspartate (NMDA) Receptor Partial Agonists
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2024, 卷号: 44, 期号: 4, 页码: 1247-1263
作者:
Wu Youjin
;
Jin Zhengsheng
;
Liu Yongjia
;
Huang Wenqian
;
Zhao Guilong
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/08/22
N-methyl-D-aspartate (NMDA) receptor
partial agonist
NYX-2925
synthesis
bioactivity
Insights into the molecular mechanism of positive cooperativity between partial agonist MK-8666 and full allosteric agonist AP8 of hGPR40 by Gaussian accelerated molecular dynamics (GaMD) simulations
期刊论文
OAI收割
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2021, 卷号: 19, 页码: 3978-3989
作者:
An, Xiaoli
;
Bai, Qifeng
;
Bing, Zhitong
;
Liu, Huanxiang
;
Yao, Xiaojun
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/12/08
hGPR40
Positive binding cooperativity
Partial agonist
AgoPAM
Gaussian accelerated molecular dynamics simulation
The anxiolytic- and antidepressant-like effects of ATPM-ET, a novel kappa agonist and mu partial agonist, in mice
期刊论文
OAI收割
PSYCHOPHARMACOLOGY, 2016, 卷号: 233, 期号: 12, 页码: 2411-2418
作者:
Wang, Qian
;
Long, Yu
;
Hang, Ai
;
Zan, Gui-Ying
;
Shu, Xiao-Hong
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
ATPM-ET
Emotional response
kappa agonist
mu partial agonist
L-Stepholidine reduced L-DOPA-induced dyskinesia in 6-OHDA-lesioned rat model of Parkinson's disease
期刊论文
OAI收割
NEUROBIOLOGY OF AGING, 2010, 卷号: 31, 期号: 6, 页码: 926-936
作者:
Mo, Jiao
;
Zhang, Hai
;
Yu, Lei-Ping
;
Sun, Pei-Hua
;
Jin, Guo-Zhang
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
L-Stepholidine
Parkinson's disease
Dyskinesia
5-HT1A receptor
Partial agonist
Design and synthesis of nitrogen-containing benzoheterocyclic derivatives and their antipsychotic activities
期刊论文
OAI收割
Acta Pharmaceutica Sinica, 2009, 卷号: 44, 期号: 9, 页码: 994-1001
作者:
PENG Shao-ping
;
YU Lei-ping
;
LI Jian-qi
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
antipsychotics
partial agonist
synthesis
Deoxyelephantopin inhibits cancer cell proliferation and functions as a selective partial agonist against PPAR gamma
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2008, 卷号: 75, 期号: 6, 页码: 1381-1392
作者:
Zou, Gang
;
Gao, Zhenting
;
Wang, Jidong
;
Zhang, Yu
;
Ding, Hong
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
deoxyelephantopin
PPAR gamma
partial agonist
surface plasmon resonance
molecular docking
Involvement of receptor reserve in d-1 agonistic action of (-)-stepholidine in lesioned rats
期刊论文
iSwitch采集
Biochemical pharmacology, 1997, 卷号: 54, 期号: 2, 页码: 233-240
作者:
Zou, LL
;
Liu, JA
;
Jin, GZ
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/05/08
(-)-stepholidine
D-1 dopamine receptor
Partial agonist
Receptor reserve
Adenylate cyclase
Rotational behavior
Involvement of receptor reserve in D-1 agonistic action of (-)-stepholidine in lesioned rats
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 1997, 卷号: 54, 期号: 2, 页码: 233-240
作者:
Zou, LL
;
Liu, JA
;
Jin, GZ
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
(-)-stepholidine
D-1 dopamine receptor
partial agonist
receptor reserve
adenylate cyclase
rotational behavior