机构

• 上海药物研究所 [6]

采集方式

• OAI收割 [6]

内容类型

• 期刊论文 [6]

发表日期

• 2025 [2]
• 2015 [2]
• 2014 [1]
• 2012 [1]

学科主题

筛选

浏览/检索结果: 共6条，第1-6条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 Guiding precision medicine strategy for intravenous ginsenosides via pharmacokinetic-informed bioinformatic approaches: a study on XueShuanTong 期刊论文  OAI收割 PHYTOMEDICINE, 2025, 卷号: 143, 页码: 18 作者:  Jia, Wei-Wei;  Tian, Nan-Nan;  Song, Zi-Jing;  Lan, Xiao-Fang;  Yang, Xi-He   |  收藏  |  浏览/下载：7/0  |  提交时间：2025/08/20 Precision medicine  Physiologically based pharmacokinetic model  Ginsenoside  Albumin-facilitated dissociation  Drug interaction  Drug transporter  Hepatic impairment   Characterization of preclinical radio ADME properties of ARV-471 for predicting human PK using PBPK modeling 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL ANALYSIS, 2025, 卷号: 15, 期号: 5, 页码: 15 作者:  He, Yifei;  Zhu, Chenggu;  Lei, Peng;  Yang, Chen;  Zhang, Yifan   |  收藏  |  浏览/下载：5/0  |  提交时间：2025/08/20 PROTAC  Vepdegestrant (ARV-471)  Radiolabeling  In vitro-in vivo extrapolation (IVIVE)  Physiologically based pharmacokinetic  (PBPK) model   Preclinical pharmacokinetics of TPN729MA, a novel PDE5 inhibitor, and prediction of its human pharmacokinetics using a PBPK model 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 12, 页码: 1528-1536 作者:  Gao, Zhi-wei;  Zhu, Yun-ting;  Yu, Ming-ming;  Zan, Bin;  Liu, Jia   |  收藏  |  浏览/下载：50/0  |  提交时间：2019/01/08 TPN729MA  PDE5 inhibitor  erectile dysfunction  pharmacokinetics  human PK prediction  physiologically based pharmacokinetic model   preclinicalpharmacokineticsoftpn729maanovelpde5inhibitorandpredictionofitshumanpharmacokineticsusingapbpkmodel 期刊论文  OAI收割 actapharmacologicasinica, 2015, 卷号: 36, 期号: 12, 页码: 1528 作者:  Gao Zhiwei;  Zhu Yunting;  Yu Mingming;  Zan Bin;  Liu Jia   |  收藏  |  浏览/下载：29/0  |  提交时间：2020/07/01 HUMAN DRUG CLEARANCE  PHOSPHODIESTERASE-5 INHIBITORS  CLINICAL PHARMACOKINETICS  ERECTILE DYSFUNCTION  TISSUE DISTRIBUTION  ORAL PHARMACOKINETICS  RECEPTOR ANTAGONIST  DIVERSE COMPOUNDS  IN-VIVO  ABSORPTION  TPN729MA  PDE5 inhibitor  erectile dysfunction  pharmacokinetics  human PK prediction  physiologically based pharmacokinetic model   Predicting pharmacokinetics of anti-cancer drug, famitinib in human using physiologically based pharmacokinetic model 期刊论文  OAI收割 Acta Pharmaceutica Sinica, 2014, 卷号: 49, 期号: 12, 页码: 1684-1688 作者:  Yu Mingming;  Gao Zhiwei;  Chen Xiaoyan;  Zhong Dafang   |  收藏  |  浏览/下载：50/0  |  提交时间：2019/01/08 famitinib  physiologically based pharmacokinetic model  species extrapolation  tyrosine kinase inhibitor   Simulation of the pharmacokinetics of bisoprolol in healthy adults and patients with impaired renal function using whole-body physiologically based pharmacokinetic modeling 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2012, 卷号: 33, 期号: 11, 页码: 1359 作者:  Li Guofu;  Wang Kun;  Chen Rui;  Zhao Haoru;  Yang Jin   |  收藏  |  浏览/下载：33/0  |  提交时间：2020/12/24 TISSUE DISTRIBUTION  DRUG DISCOVERY  INTRASUBJECT VARIABILITY  PBPK SIMULATION  P-GP  ABSORPTION  POPULATION  PREDICTION  BIOAVAILABILITY  IDENTIFICATION  bisoprolol  whole-body physiologically based pharmacokinetic model  drug absorption  drug distribution  renal function impairment