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Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [9]
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OAI收割 [18]
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期刊论文 [18]
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Identification and characterization of Gd-binding proteins in NIH-3T3 cells
期刊论文
OAI收割
TALANTA, 2020, 卷号: 219, 页码: 1-8
作者:
Nong, Qiying
;
Chen, Xi
;
Hu, Ligang
;
Huang, Yongshun
;
Luan, Tiangang
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/09/14
Gadolinium
Gadolinium-based contrast agents
Gd-binding protein
NIH-3T3 cell
Tubulin
Toxicity
The Structure of MT189-Tubulin Complex Provides Insights into Drug Design
期刊论文
OAI收割
LETTERS IN DRUG DESIGN & DISCOVERY, 2019, 卷号: 16, 期号: 9, 页码: 1069-1073
作者:
Li, Zhongping
;
Ma, Lingling
;
Wu, Chengyong
;
Meng, Tao
;
Ma, Lanping
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/07/01
Crystal structure
tubulin
colchicine binding site
inhibitor
MT189
drug design
Discovery of novel 2-phenyl-imidazo[1,2-a]pyridine analogues targeting tubulin polymerization as antiproliferative agents
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 112, 页码: 367-372
作者:
An, Weiteng
;
Wang, Wei
;
Yu, Ting
;
Zhang, Yongliang
;
Miao, Zehong
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
Anticancer agents
Tubulin inhibitor
Intra-molecular hydrogen bonding
Colchicine binding site
Identification of novel microtubule-binding proteins by taxol-mediated microtubule stabilization and mass spectrometry analysis
期刊论文
OAI收割
THORACIC CANCER, 2015, 卷号: 6, 期号: 5, 页码: 649-654
作者:
He, Xianfei
;
Liu, Zhu
;
He, Qianqian
;
Qin, Juan
;
Liu, Ningning
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2016/06/23
Mass spectrometry
microtubule
microtubule-binding protein
taxol
tubulin
Synthesis and biological evaluation of 6H-pyrido[2 ',1 ':2,3] imidazo[4,5-c] isoquinolin-5(6H)-ones as antimitotic agents and inhibitors of tubulin polymerization
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 2, 页码: 848-855
作者:
Meng, Tao
;
Wang, Wei
;
Zhang, Zhixiang
;
Ma, Lanping
;
Zhang, Yongliang
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
6H-Pyrido[2 ',1 ':2,3]imidazo[4,5-c]
isoquinolin-5(6H)-ones
Antitumor agents
Inhibitors of tubulin polymerization
Colchicine binding site
Molecular dynamics simulation and density functional theory studies on the active pocket for the binding of paclitaxel to tubulin
期刊论文
OAI收割
JOURNAL OF MOLECULAR MODELING, 2012, 卷号: 18, 期号: 1, 页码: 377-391
作者:
Xu, Sichuan
;
Chi, Shaoming
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/04/09
Paclitaxel
Tubulin
Binding Pocket
Md Simulation
Dft
Novel microtubule-targeted agent 6-chloro-4-(methoxyphenyl) coumarin induces G_2-M arrest and apoptosis in HeLa cells
期刊论文
OAI收割
Acta Pharmacologica Sinica, 2012, 卷号: 33, 期号: 3, 页码: 407
作者:
Ma Yiming
;
Zhou Yubo
;
Xie Chuanming
;
Chen Dongmei
;
Li Jia
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
ACTIVATED PROTEIN-KINASE
TUBULIN-BINDING AGENT
IN-VIVO
ANTIMICROBIAL ACTIVITY
ANTICANCER ACTIVITY
CYCLE ARREST
CANCER-CELLS
DERIVATIVES
INHIBITOR
RESISTANT
anticancer drug
6-chloro-4-(methoxyphenyl) coumarin
cell cycle arrest
microtubule depolymerization
apoptosis
anovelsulfonamideagentmpsp001exhibitspotentactivityagainsthumancancercellsinvitrothroughdisruptionofmicrotubule
期刊论文
OAI收割
actapharmacologicasinica, 2012, 卷号: 33, 期号: 2, 页码: 261
作者:
Liu Zulong
;
Tian Wei
;
Wang Yong
;
Kuang Shan
;
Luo Xiaomin
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
PHASE-I
ANTITUMOR-ACTIVITY
ANTICANCER AGENT
DRUG-RESISTANCE
SOLID TUMORS
BINDING
APOPTOSIS
TUBULIN
E7070
COLCHICINE
MPSP-001
sulfonamide
anticancer drug
microtubules
tubulin
mitotic spindle
drug resistance
drug synergism
A novel sulfonamide agent, MPSP-001, exhibits potent activity against human cancer cells in vitro through disruption of microtubule
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2012, 卷号: 33, 期号: 2, 页码: 261-270
作者:
Liu Zulong
;
Tian Wei
;
Wang Yong
;
Kuang Shan
;
Luo Xiaomin
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2021/02/02
PHASE-I
ANTITUMOR-ACTIVITY
ANTICANCER AGENT
BINDING
APOPTOSIS
E7070
COLCHICINE
DISCOVERY
HMN-214
CAMPTOTHECIN
MPSP-001
sulfonamide
anticancer drug
microtubules
tubulin
mitotic spindle
drug resistance
drug synergism