中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [141]
西双版纳热带植物园 [12]
西北高原生物研究所 [11]
水生生物研究所 [11]
武汉植物园 [10]
植物研究所 [8]
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OAI收割 [257]
内容类型
期刊论文 [244]
学位论文 [7]
SCI/SSCI论文 [3]
会议论文 [3]
发表日期
2012 [257]
学科主题
Environmen... [3]
Fisheries [3]
Marine & F... [3]
Immunology [2]
Veterinary... [2]
物理化学 [2]
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发表日期:2012
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OVEREXPRESSION OF MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 2 IN THE BRAIN OF PENTYLENETETRAZOLE-KINDLED RATS
期刊论文
OAI收割
NEUROSCIENCE, 2012, 卷号: 227, 页码: 283-292
作者:
Yao, D.
;
Liu, L.
;
Jin, S.
;
Li, J.
;
Liu, X. -D.
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
multidrug resistance-associated protein 2
pharmacoresistant epilepsy
phenytoin
blood-brain barrier
anti-epileptic effect
Methylphenidate Enhances NMDA-Receptor Response in Medial Prefrontal Cortex via Sigma-1 Receptor: A Novel Mechanism for Methylphenidate Action
期刊论文
OAI收割
PLOS ONE, 2012, 卷号: 7, 期号: 12
作者:
Zhang, Chun-Lei
;
Feng, Ze-Jun
;
Liu, Yue
;
Ji, Xiao-Hua
;
Peng, Ji-Yun
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Discovery of di-indolinone as a novel scaffold for protein tyrosine phosphatase 1B inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 24, 页码: 7440-7443
作者:
Dai, Hou-ling
;
Gao, Li-xin
;
Yang, Ying
;
Li, Jing-ya
;
Cheng, Jia-gao
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Protein tyrosine phosphatase 1B
Molecular docking
Inhibitors
Di-indolinone
Cyanobacterial Peptides as a Prototype for the Design of Potent beta-Secretase Inhibitors and the Development of Selective Chemical Probes for Other Aspartic Proteases
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 55, 期号: 23, 页码: 10749-10765
作者:
Liu, Yanxia
;
Zhang, Wei
;
Li, Li
;
Salvador, Lilibeth A.
;
Chen, Tiantian
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
Reversal of P-gp and MRP1-mediated multidrug resistance by H6, a gypenoside aglycon from Gynostemma pentaphyllum, in vincristine-resistant human oral cancer (KB/VCR) cells
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACOLOGY, 2012, 卷号: 696, 期号: 1-3, 页码: 43-53
作者:
Zhu, Hengrui
;
Liu, Zulong
;
Tang, Lisha
;
Liu, Junhua
;
Zhou, Mei
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Gypenoside aglycon
Gynostemma pentaphyllum
Multidrug resistance (MDR)
KB/VCR cells
P-glycoprotein (P-gp)
Multidrug resistance associated protein 1 (MRP1)
Effect of size and dose on the biodistribution of graphene oxide in mice
期刊论文
OAI收割
NANOMEDICINE, 2012, 卷号: 7, 期号: 12, 页码: 1801-1812
作者:
Liu, Jia-Hui
;
Yang, Sheng-Tao
;
Wang, Haifang
;
Chang, Yanli
;
Cao, Aoneng
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/04/09
Biodistribution
Dose
Graphene Oxide
Isotope Labeling
Size Effect
Inhibitors of HIV-1 Integrase-Human LEDGF/p75 Interaction Identified from Natural Products via Virtual Screening
期刊论文
OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2012, 卷号: 30, 期号: 12, 页码: 2752-2758
作者:
Hu Guoping
;
Li Xi
;
Li Yaozong
;
Sun Xianqiang
;
Liu Guixia
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
natural products
virtual screening
protein-protein interaction
HIV-1 integrase
human LEDGF
p75 protein
L655,240, acting as a competitive BACE1 inhibitor, efficiently decreases beta-amyloid peptide production in HEK293-APPswe cells
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2012, 卷号: 33, 期号: 12, 页码: 1459-1468
作者:
Lu, Qin
;
Chen, Wu-yan
;
Zhu, Zhi-yuan
;
Chen, Jing
;
Xu, Ye-chun
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
L655,240
Alzheimer's disease
BACE1
beta-amyloid peptide
HEK293-APPswe cells
Identification of old drugs as potential inhibitors of HIV-1 integrase - human LEDGF/p75 interaction via molecular docking
期刊论文
OAI收割
JOURNAL OF MOLECULAR MODELING, 2012, 卷号: 18, 期号: 12, 页码: 4995-5003
作者:
Hu, Guoping
;
Li, Xi
;
Sun, Xianqiang
;
Lu, Weiqiang
;
Liu, Guixia
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
Drug repositioning
HIV-1 Integrase
Human LEDGF/p75 protein
Molecular docking
Protein-protein interaction
Biochemical properties and catalytic domain structure of the CcmH protein from Escherichia coli
期刊论文
OAI收割
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2012, 卷号: 1824, 期号: 12, 页码: 1394-1400
作者:
Zheng, Xue-Ming
;
Hong, Jing
;
Li, Hai-Yin
;
Lin, Dong-Hai
;
Hu, Hong-Yu
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
CcmH protein
topology
solution structure
redox potential
cytochrome c maturation
periplasm