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Chinese Academy of Sciences Institutional Repositories Grid
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Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses
期刊论文
OAI收割
NATURE CHEMICAL BIOLOGY, 2024, 页码: 29
作者:
Zhou, Xiaoyu
;
Zhao, Cheng
;
Xu, Haiyan
;
Xu, Yixiang
;
Zhan, Li
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/25
Distinct resting-state functional connectivity of the anterior cingulate cortex subregions in first-episode schizophrenia
期刊论文
OAI收割
BRAIN IMAGING AND BEHAVIOR, 2024, 页码: 11
作者:
Huang, Huan
;
Chen, Cheng
;
Rong, Bei
;
Zhou, Yuan
;
Yuan, Wei
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/03/25
Anterior cingulate cortex
Schizophrenia
Resting-state functional connectivity.
Discovery of Novel PROTAC Degraders of p300/CBP as Potential Therapeutics for Hepatocellular Carcinoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2466-2486
作者:
Chang, Qi
;
Li, Jiayi
;
Deng, Yue
;
Zhou, Ruilin
;
Wang, Bingwei
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/25
Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17
作者:
Lan, Yaohan
;
Peng, Xia
;
Ji, Yinchun
;
Su, Yi
;
Duan, Wenhu
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
AXL inhibitor
In vivo antitumor efficacy
6-Naphthyridin-4-one derivatives
Scaffold hopping
Structure-based drug design
Bialorastins A-F, highly oxygenated and polycyclic andrastin-type meroterpenoids with proangiogenic activity from the deep-sea cold-seep-derived fungus Penicillium bialowiezense CS-283
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 12
作者:
Yan, Li-Hong
;
Li, Pei-Hai
;
Li, Xiao-Ming
;
Yang, Sui-Qun
;
Liu, Ke-Chun
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/04/07
Cold-seep
Penicillium bialowiezense
Meroterpenoids
Proangiogenic activity
Safety, pharmacokinetics, and food effect of sudapyridine (WX-081), a novel anti-tuberculosis candidate in healthy Chinese subjects
期刊论文
OAI收割
CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 2024, 卷号: 17, 期号: 2, 页码: 10
作者:
Yu, Chengyin
;
Qian, Hongjie
;
Wu, Qingqing
;
Zou, Yang
;
Ding, Qicheng
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/03/06
Pharmacologically significant constituents collectively responsible for anti-sepsis action of XueBiJing, a Chinese herb-based intravenous formulation
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 16
作者:
Cheng, Chen
;
Ren, Chao
;
Li, Mu-zi
;
Liu, Yi-hui
;
Yao, Ren-qi
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/02/27
Traditional Chinese medicine
XueBiJing
sepsis
mortality
pharmacokinetic compatibility
polypharmacology
Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity
in
vitro
and
in
vivo
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 98, 页码: 7
作者:
Dong, Sanfeng
;
Hu, Ke
;
Shi, Yulong
;
Wang, Guanli
;
Yu, Dandan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/02/19
Multiple myeloma
TRIP13 inhibitor
Cantharidin
DCZ5418
DCZ0415
Integrated biomarker response to assess toxic impacts of iron and manganese on deep-sea mussel
Gigantidas platifrons
under a deep-sea mining activity scenario
期刊论文
OAI收割
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2024, 页码: 11
作者:
Zhou, Li
;
Li, Mengna
;
Zhong, Zhaoshan
;
Wang, Minxiao
;
Chen, Hao
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/04/07
mussel
metal
deep-sea mining
biomarker
environmental monitoring
Low-Dose Chemotherapy Preferentially Shapes the Ileal Microbiome and Augments the Response to Immune Checkpoint Blockade by Activating AIM2 Inflammasome in Ileal Epithelial Cells
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 17
作者:
Pu, Congying
;
Li, Yize
;
Fu, Yixian
;
Yan, Yiyang
;
Tao, Siyao
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/02/27
AIM2 inflammasome
chemotherapy
gut microbiome
ileal epithelial cells
immune checkpoint blockade
lactobacillus
segmented filamentous bacterium