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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [44]
采集方式
OAI收割 [44]
内容类型
期刊论文 [44]
发表日期
2018 [44]
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发表日期:2018
专题:上海药物研究所
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Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3693-3699
作者:
Zhu, Kongkai
;
Song, Jia-Li
;
Tao, Hong-Rui
;
Cheng, Zhi-Qiang
;
Jiang, Cheng-Shi
  |  
收藏
  |  
浏览/下载:100/0
  |  
提交时间:2019/01/08
Pharmacophore combination
Isoquinoline
PRMT5 inhibitor
Molecular docking
Molecular dynamics simulation
Identification of 5-benzylidene-2-phenylthiazolones as potent PRMT5 inhibitors by virtual screening, structural optimization and biological evaluations
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2018, 卷号: 81, 页码: 289-298
作者:
Zhu, Kongkai
;
Tao, Hongrui
;
Song, Jia-Li
;
Jin, Lu
;
Zhang, Yuanyuan
  |  
收藏
  |  
浏览/下载:129/0
  |  
提交时间:2019/01/08
PRMT5 inhibitor
Arginine methylation
Virtual screening
Molecular docking
Molecular dynamics simulation
Restoration of sternness-high tumor cell-mediated suppression of murine dendritic cell activity and inhibition of tumor growth by low molecular weight oyster polysaccharide
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2018, 卷号: 65, 页码: 221-232
作者:
Zhong, Ming
;
Zhong, Cheng
;
Hu, Pei
;
Cui, Wen
;
Wang, Guanghui
  |  
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2019/01/08
Colorectal cancer stem cells
Dendritic cells
TGF-beta
NF-kappa B
Oyster polysaccharide
Synthesis of novel tetrandrine derivatives and their inhibition against NSCLC A549 cells
期刊论文
OAI收割
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2018, 卷号: 20, 期号: 11, 页码: 1064-1074
作者:
Yang, Qian-Hao
;
Jiang, Cheng-Shi
;
Jin, Tao
;
Xu, Jin-Fang
;
Qu, Ting-Li
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
Tetrandrine derivatives
non-small cell lung carcinoma
NSCLC A549 cells
anticancer activities
Suzuki-Miyaura reaction
Molecular-docking-guided design and synthesis of new IAA-tacrine hybrids as multifunctional AChE/BChE inhibitors
期刊论文
OAI收割
Bioorganic chemistry, 2018, 卷号: 83, 页码: 277-288
作者:
Cheng, Zhi-Qiang
;
Zhu, Kong-Kai
;
Zhang, Juan
;
Song, Jia-Li
;
Muehlmann, Luis Alexandre
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/01/08
The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis
期刊论文
OAI收割
IMMUNITY, 2018, 卷号: 49, 期号: 4, 页码: 740-+
作者:
Deng, Meihong
;
Tang, Yiting
;
Li, Wenbo
;
Wang, Xiangyu
;
Zhang, Rui
  |  
收藏
  |  
浏览/下载:110/0
  |  
提交时间:2019/01/08
Advances on genotoxic impurities of sulfonate esters in pharmaceuticals
期刊论文
OAI收割
Se pu = Chinese journal of chromatography, 2018, 卷号: 36, 期号: 10, 页码: 952-961
作者:
Liu, Xuewei
;
Li, Cheng
;
Han, Haiyun
;
Zhang, Wenpeng
;
Chen, Dongying
  |  
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2019/01/08
Design, synthesis and anti leukemia cells proliferation activities of pyrimidylaminoquinoline derivatives as DOT1L inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2018, 卷号: 80, 页码: 649-654
作者:
Zhang, Li
;
Chen, Yantao
;
Liu, Na
;
Li, Linjuan
;
Xiao, Senhao
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/01/08
Pyrimidylaminoquinoline
Nonnucleoside DOT1L inhibitors
Amino side chains
Mixed-linage leukemia
Histone lysine methyltransferase
Comparative in vivo constituents and pharmacokinetic study in rats after oral administration of ultrafine granular powder and traditional decoction slices of Chinese Salvia
期刊论文
OAI收割
Biomedical chromatography : BMC, 2018, 页码: e4385
作者:
Zhi, Haijuan
;
Li, Zhenwei
;
Deng, Yanping
;
Qi, Peng
;
Hou, Jinjun
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
Identification of small molecule inhibitors targeting the SMARCA2 bromodomain from a high-throughput screening assay
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 9, 页码: 1544-1552
作者:
Lu, Tian
;
Hu, Jun-chi
;
Lu, Wen-chao
;
Han, Jie
;
Ding, Hong
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
AlphaScreen
high-throughput screening
SMARCA2
bromodomain
small molecule inhibitor