机构

• 上海药物研究所 [18]

采集方式

• OAI收割 [18]

内容类型

• 期刊论文 [18]

发表日期

• 2019 [18]

学科主题

筛选

浏览/检索结果: 共18条，第1-10条 帮助 限定条件 发表日期：2019    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 15 作者:  Lu, Wenchao;  Wang, Jun;  Li, Yong;  Tao, Hongru;  Xiong, Huan   |  收藏  |  浏览/下载：83/0  |  提交时间：2020/07/01 Hippo pathway  TEAD transcription factor  Covalent inhibitor  Palmitoylation inhibitor   GIAT4RA functions as a tumor suppressor in non-small cell lung cancer by counteracting Uchl3-mediated deubiquitination of LSH 期刊论文  OAI收割 ONCOGENE, 2019, 卷号: 38, 期号: 46, 页码: 7133-7145 作者:  Yang, Rui;  Liu, Na;  Chen, Ling;  Jiang, Yiqun;  Shi, Ying   |  收藏  |  浏览/下载：25/0  |  提交时间：2020/07/01 The Study of Release Mechanisms for Drug in Cyclodextrin Metal-Organic Frameworks 期刊论文  OAI收割 ACS OMEGA, 2019, 卷号: 4, 期号: 11, 页码: 14490-14496 作者:  Liu, Congbiao;  Guo, Tao;  Li, Weimin;  Jiang, Zhiteng;  Chen, Min   |  收藏  |  浏览/下载：15/0  |  提交时间：2020/07/01 Interplay between the bacterial protein deacetylase CobB and the second messenger c-di-GMP 期刊论文  OAI收割 EMBO JOURNAL, 2019, 页码: 18 作者:  Xu, Zhaowei;  Zhang, Hainan;  Zhang, Xingrun;  Jiang, Hewei;  Liu, Chengxi   |  收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01 c-di-GMP  CobB  diguanylate cyclase  negative feedback loop  protein acetylation   Disulfide-Containing Detergents (DCDs) for the Structural Biology of Membrane Proteins 期刊论文  OAI收割 CHEMISTRY-A EUROPEAN JOURNAL, 2019, 页码: 7 作者:  Xue, Dongxiang;  Xu, Tiandan;  Wang, Huixia;  Wu, Meng;  Yuan, Ya   |  收藏  |  浏览/下载：21/0  |  提交时间：2020/07/01 detergents  disulfides  membrane proteins  micelle size  NMR spectroscopy   Trained Macrophage Bioreactor for Penetrating Delivery of Fused Antitumor Protein 期刊论文  OAI收割 ACS APPLIED MATERIALS & INTERFACES, 2019, 卷号: 11, 期号: 26, 页码: 23018-23025 作者:  Zhang, Yu;  Zhang, Yujie;  Guo, Qin;  Guo, Zhongyuan;  Chen, Xinli   |  收藏  |  浏览/下载：33/0  |  提交时间：2020/07/01 macromolecular protein delivery  cell vector  tumor targeting  intratumoral drug distribution  breast cancer therapy   Discovery of New Selective Butyrylcholinesterase (BChE) Inhibitors with Anti-A beta Aggregation Activity: Structure-Based Virtual Screening, Hit Optimization and Biological Evaluation 期刊论文  OAI收割 MOLECULES, 2019, 卷号: 24, 期号: 14, 页码: 21 作者:  Jiang, Cheng-Shi;  Ge, Yong-Xi;  Cheng, Zhi-Qiang;  Wang, Yin-Yin;  Tao, Hong-Rui   |  收藏  |  浏览/下载：21/0  |  提交时间：2020/07/01 selective BChE inhibitor  virtual screening  structural optimization  molecular dynamics  anti-A beta aggregation   Discovery of (R)-5-((5-(1-methyl-1H-pyrazol-4-yl)-4-(methylamino) pyrimidin-2-yl)amino)-3-(piperidin-3-yloxy)picolinonitrile, a novel CHK1 inhibitor for hematologic malignancies 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 173, 页码: 44-62 作者:  Tong, Lexian;  Song, Pinrao;  Jiang, Kailong;  Xu, Lei;  Jin, Tingting   |  收藏  |  浏览/下载：24/0  |  提交时间：2020/07/01 CHK1 kinase inhibitor  Selectivity  Monotherapy  Hematologic malignancies   Development of Small-Molecules Targeting Receptor Activator of Nuclear Factor-kappa B Ligand (RANKL)-Receptor Activator of Nuclear Factor-kappa B (RANK) Protein-Protein Interaction by Structure-Based Virtual Screening and Hit Optimization 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5370-5381 作者:  Jiang, Min;  Peng, Lei;  Yang, Kai;  Wang, Tianqi;  Yan, Xueming   |  收藏  |  浏览/下载：17/0  |  提交时间：2020/07/01 Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure-based virtual screening 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2019, 卷号: 86, 页码: 494-500 作者:  Zhang, Dan;  Han, Jie;  Lu, Wenchao;  Lian, Fulin;  Wang, Jun   |  收藏  |  浏览/下载：30/0  |  提交时间：2020/07/01 Lysine acetylation  Bromodomain  Virtual screening  BPTF inhibitor