机构

• 上海药物研究所 [13]

采集方式

• OAI收割 [13]

内容类型

• 期刊论文 [13]

发表日期

• 2023 [2]
• 2022 [2]
• 2021 [1]
• 2019 [3]
• 2018 [1]
• 2017 [2]
• 更多

学科主题

筛选

浏览/检索结果: 共13条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 Bispecific antibody targeting both B7-H3 and PD-L1 exhibits superior antitumor activities 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 9 作者:  Li, Hua-ying;  Chen, Yi-li;  Deng, Xiang-nan;  Li, Huan-huan;  Tan, Jie   |  收藏  |  浏览/下载：28/0  |  提交时间：2023/10/17 cancer immunotherapy  B7-H3  PD-L1  bispecific antibodies  VHH  antibody-dependent cell-mediated cytotoxicity (ADCC)   Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance 期刊论文  OAI收割 EMBO MOLECULAR MEDICINE, 2023, 页码: 24 作者:  Wang, Li-Min;  Wang, Pingyuan;  Chen, Xiao-Min;  Yang, Hui;  Song, Shan-Shan   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/04/10 homologous recombination repair  olaparib-resistant  PARP inhibitor  PARP7  type I interferons   Structure-Based Design of Tropane Derivatives as a Novel Series of CCR5 Antagonists with Broad-Spectrum Anti-HIV-1 Activities and Improved Oral Bioavailability 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 24, 页码: 16526-16540 作者:  Xie, Xiong;  Zheng, Yu-Gui;  Chen, Huan;  Li, Jian;  Luo, Rong-Hua   |  收藏  |  浏览/下载：26/0  |  提交时间：2023/04/10 SOMCL-19-133, a novel, selective, and orally available inhibitor of NEDD8-activating enzyme (NAE) for cancer therapy 期刊论文  OAI收割 NEOPLASIA, 2022, 卷号: 32, 页码: 12 作者:  Zhou, Li-Na;  Xiong, Chaodong;  Cheng, Yong-Jun;  Song, Shan-Shan;  Bao, Xu-Bin   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/04/10 SOMCL-19-133  NAE inhibitor  MLN4924  NEDD8  Oral administration   Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 10, 页码: 3206-3219 作者:  Lu, Tian;  Li, Yong;  Lu, Wenchao;  Spitters, Twgm;  Fang, Xueyu   |  收藏  |  浏览/下载：45/0  |  提交时间：2021/12/01 Hippo pathway  TEAD3  Covalent inhibitor  Palmitoylation inhibitor   Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 15 作者:  Lu, Wenchao;  Wang, Jun;  Li, Yong;  Tao, Hongru;  Xiong, Huan   |  收藏  |  浏览/下载：83/0  |  提交时间：2020/07/01 Hippo pathway  TEAD transcription factor  Covalent inhibitor  Palmitoylation inhibitor   Metal-free quinolylation of the primary amino groups of amino acid derivatives and peptides with dihydrooxazolo[3,2-a]quinoliniums 期刊论文  OAI收割 GREEN CHEMISTRY, 2019, 卷号: 21, 期号: 15, 页码: 4231-4237 作者:  Liu, Peng;  Li, Bo;  Xi, Mengyu;  Chen, Zhaoqiang;  Sun, Haiguo   |  收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01 Characterization of drug-drug salt forms of metformin and aspirin with improved physicochemical properties 期刊论文  OAI收割 CRYSTENGCOMM, 2019, 卷号: 21, 期号: 25, 页码: 3770-3773 作者:  Zhou, Wen-Xiu;  Zhao, Hong-Wei;  Chen, Huan-Huan;  Zhang, Zai-Yong;  Chen, Dong-Ying   |  收藏  |  浏览/下载：12/0  |  提交时间：2020/07/01 Structure-Based Design of 1-Heteroary1-1,3-propanediamine Derivatives as a Novel Series of CC-Chemokine Receptor 5 Antagonists 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 21, 页码: 9621-9636 作者:  Peng, Panfeng;  Chen, Huan;  Zhu, Ya;  Wang, Zhilong;  Li, Jian   |  收藏  |  浏览/下载：56/0  |  提交时间：2019/01/08 Discovery, mechanism and metabolism studies of 2,3-difluorophenyl-linker-containing PARP1 inhibitors with enhanced in vivo efficacy for cancer therapy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138, 页码: 514-531 作者:  Chen, Wenhua;  Guo, Ne;  Qi, Minghui;  Dai, Haiying;  Hong, Minghuang   |  收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08 Antitumor drug  BRCA1/2  PARP inhibitors  Molecular docking