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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [498]
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OAI收割 [498]
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期刊论文 [494]
会议论文 [4]
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2024 [20]
2023 [40]
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Chemistry [9]
Pharmacolo... [8]
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浏览/检索结果:
共498条,第1-10条
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专题:上海药物研究所
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Biotransformation and disposition characteristics of HSK7653, a novel long-acting dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes
期刊论文
OAI收割
DIABETES OBESITY & METABOLISM, 2024, 页码: 9
作者:
Bian, Yi-cong
;
Meng, Jian
;
Hu, Tao
;
Ma, Sheng
;
Huang, Chen-rong
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/22
HSK7653
long-acting dipeptidyl peptidase-4 inhibitor
mass balance
metabolism
pharmacokinetics
radiolabelled
Visible Light-Mediated Defluorination to Access 1,1-Difluoro-1,3-Enynes
期刊论文
OAI收割
ADVANCED SYNTHESIS & CATALYSIS, 2024, 页码: 7
作者:
Wang, Xu
;
Huang, Wei
;
Zhang, Feng-Hua
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
photoredox catalysis
1,1-difluoro-1,3-enynes
acid
metal free
redox-neutral
Design, Synthesis, and Pharmacological Evaluation of Spiro[carbazole-3,3′-pyrrolidine] Derivatives as cGAS Inhibitors for Treatment of Acute Lung Injury
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 24
作者:
Chen, Mingjie
;
Lei, Shuyue
;
Zhou, Zihua
;
Wang, Meng
;
Feng, Chunlan
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12
作者:
Zou, Zhi-feng
;
Yang, Lei
;
Nie, Hui-jun
;
Gao, Jing
;
Lei, Shu-min
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
proteolysis-targeting chimeras
tumor-targeted delivery
precise protein degradation
combination therapy
triple-negative breast cancer
Dihydrocelastrol induces cell death and suppresses angiogenesis through BCR/AP-1/junb signalling in diffuse large B cell lymphoma
期刊论文
OAI收割
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2024, 卷号: 754, 页码: 11
作者:
Lai, Yue
;
Guo, Shushan
;
Tang, Qiongwei
;
Chang, Gaomei
;
Zhang, Hui
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/07
Dihydrocelastrol
Angiogenesis
Apoptosis
Jun B
p65
Integrated multi-omics analysis reveals gut microbiota dysbiosis and systemic disturbance in major depressive disorder
期刊论文
OAI收割
PSYCHIATRY RESEARCH, 2024, 卷号: 334, 页码: 12
作者:
Xie, Zuoquan
;
Huang, Jingjing
;
Sun, Guangqiang
;
He, Shen
;
Luo, Zhiyu
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/22
Major depressive disorder
Peripheral changes
Gut microbiota
Immune phenotyping
Multiomics
Biomarkers
RIPK1 inhibitor ameliorates pulmonary injury by modulating the function of neutrophils and vascular endothelial cells
期刊论文
OAI收割
CELL DEATH DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 12
作者:
Yang, Tao
;
Xiang, Cai-gui
;
Wang, Xiao-han
;
Li, Qing-qing
;
Lei, Shu-yue
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/07
Excessive fatty acids activate PRMT5/MDM2/Drosha pathway to regulate miRNA biogenesis and lipid metabolism
期刊论文
OAI收割
LIVER INTERNATIONAL, 2024, 页码: 17
作者:
Hou, Aijun
;
Xu, Xiaoding
;
Zhang, Yu
;
He, Hongxiu
;
Feng, Yihan
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Drosha degradation
lipid metabolism
miRNA biogenesis
NAFLD
PRMT5
Identification of Dihydrobenzofuran Neolignans as Novel PDE4 Inhibitors and Evaluation of Antiatopic Dermatitis Efficacy in DNCB-Induced Mice Model
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4855-4869
作者:
Gu, Chenming
;
Liu, Jiayuan
;
Qian, Fei
;
Yu, Wenchao
;
Huang, Doudou
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Site- and Stereoselective Glycomodification of Biomolecules through Carbohydrate-Promoted Pictet-Spengler Reaction
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2024, 页码: 11
作者:
Liu, Bo
;
Zou, Xiangman
;
Zhang, Yue
;
Yang, Yang
;
Xu, Hao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07