中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [101]
采集方式
OAI收割 [101]
内容类型
期刊论文 [101]
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2024 [2]
2023 [15]
2022 [11]
2021 [12]
2020 [14]
2019 [10]
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Pharmacolo... [2]
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Research &... [1]
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专题:上海药物研究所
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Discovery of a Covalent Inhibitor Selectively Targeting the Autophosphorylation Site of c-Src Kinase
期刊论文
OAI收割
ACS CHEMICAL BIOLOGY, 2024, 页码: 12
作者:
Zhang, Huimin
;
Xu, Dounan
;
Huang, Hongchan
;
Jiang, Hao
;
Hu, Linghao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Spatiotemporal and direct capturing global substrates of lysine-modifying enzymes in living cells
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1, 页码: 15
作者:
Hu, Hao
;
Hu, Wei
;
Guo, An-Di
;
Zhai, Linhui
;
Ma, Song
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Exploring the mechanism of the PTP1B inhibitors by molecular dynamics and experimental study
期刊论文
OAI收割
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 125, 页码: 12
作者:
Zhao, Tian-Tian
;
Hu, Hao-Jie
;
Gao, Li-Xin
;
Zhou, Yu-Bo
;
Zhu, Yun-Long
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Protein tyrosine phosphatases inhibitors
PTP1B inhibitors
Mechanism study
Molecular dynamics
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Clinically Translatable Solid-State Dye for NIR-II Imaging of Medical Devices
期刊论文
OAI收割
ADVANCED SCIENCE, 2023, 页码: 13
作者:
Li, Deling
;
Shi, Hui
;
Qi, Qingrong
;
Chang, Baisong
;
Jiang, Yuanwen
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/19
aggregates
in vivo imaging
medical devices
NIR-II fluorescence
Anxiolytic effect of antidiabetic metformin is mediated by AMPK activation in mPFC inhibitory neurons
期刊论文
OAI收割
MOLECULAR PSYCHIATRY, 2023, 页码: 11
作者:
Zhang, Yong-mei
;
Zong, Hai-chao
;
Qi, Ying-bei
;
Chang, Liu-liu
;
Gao, Ya-nan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/12/08
Deciphering the functional landscape of phosphosites with deep neural network
期刊论文
OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 9, 页码: 23
作者:
Liang, Zhongjie
;
Liu, Tonghai
;
Li, Qi
;
Zhang, Guangyu
;
Zhang, Bei
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/08
Hyodeoxycholic acid ameliorates nonalcoholic fatty liver disease by inhibiting RAN-mediated PPARa nucleus-cytoplasm shuttling
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 18
作者:
Zhong, Jing
;
He, Xiaofang
;
Gao, Xinxin
;
Liu, Qiaohong
;
Zhao, Yu
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/12/08
Spectral and biodistributional engineering of deep near-infrared chromophore
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2023, 卷号: 34, 期号: 9, 页码: 7
作者:
Dong, Yan
;
Lu, Xicun
;
Li, Yi
;
Chen, Weichao
;
Yin, Lei
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
Near infrared fluorophore
In vivo imaging
Molecular engineering
Biological distribution
Angiography
Investigation of targets and anticancer mechanisms of covalently acting natural products by functional proteomics
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 8, 页码: 1701-1711
作者:
Zhao, Wen-si
;
Chen, Kai-feng
;
Liu, Man
;
Jia, Xing-long
;
Huang, Yu-qi
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
natural products
proteomics
ABPP
eriocalyxin B
parthenolide