中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [274]
采集方式
OAI收割 [274]
内容类型
期刊论文 [268]
会议论文 [6]
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2024 [9]
2023 [19]
2022 [18]
2021 [32]
2020 [19]
2019 [21]
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浏览/检索结果:
共274条,第1-10条
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专题:上海药物研究所
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SRY-Box transcription factor 9 triggers YAP nuclear entry via direct interaction in tumors
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 13
作者:
Qian, Hui
;
Ding, Chen-Hong
;
Liu, Fang
;
Chen, Shi-Jie
;
Huang, Chen-Kai
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
Discovery of YFJ-36: Design, Synthesis, and Antibacterial Activities of Catechol-Conjugated β-Lactams against Gram-Negative Bacteria
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 21
作者:
Liu, Fangjun
;
Kou, Qunhuan
;
Li, Hongyuan
;
Cao, Yangzhi
;
Chen, Meng
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
Discovery and Optimization of Novel Nonbile Acid FXR Agonists as Preclinical Candidates for the Treatment of Inflammatory Bowel Disease
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 7, 页码: 5642-5661
作者:
Li, Yuan
;
Xu, Tingting
;
Zhao, Yue
;
Zhang, Hui
;
Liu, Zesheng
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/05/07
Functional analysis of CYP71AV1 reveals the evolutionary landscape of artemisinin biosynthesis
期刊论文
OAI收割
FRONTIERS IN PLANT SCIENCE, 2024, 卷号: 15, 页码: 9
作者:
Chen, Fang-Yan
;
Mu, Qiu-Yan
;
Xu, Bing-Yi
;
Lei, Yu-Chen
;
Liu, Hui-Ying
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
artemisinin
Asteraceae sesquiterpene lactone
cytochrome P450 monooxygenases
amorpha-4
11-diene oxidase
germacrene A oxidase
molecular evolution
loss-of-function event
Quantitative proteomics reveals the protective effects of Yinchenzhufu decoction against cholestatic liver fibrosis in mice by inhibiting the PDGFRβ/PI3K/AKT pathway
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15, 页码: 13
作者:
Meng, Qian
;
Zhu, Hongwen
;
Li, Yuanyuan
;
Peng, Xiaotian
;
Wang, Tianming
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Yinchenzhufu decoction
proteomics
cholestasis
liver fibrosis
PDGFR beta/PI3K/AKT
Spatiotemporal and direct capturing global substrates of lysine-modifying enzymes in living cells
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1, 页码: 15
作者:
Hu, Hao
;
Hu, Wei
;
Guo, An-Di
;
Zhai, Linhui
;
Ma, Song
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
An LQT2-related mutation in the voltage-sensing domain is involved in switching the gating polarity of hERG
期刊论文
OAI收割
BMC BIOLOGY, 2024, 卷号: 22, 期号: 1, 页码: 14
作者:
Liu, Zhipei
;
Wang, Feng
;
Yuan, Hui
;
Tian, Fuyun
;
Yang, Chuanyan
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/03/13
hERG
K525N
Gating Polarity
Voltage-Sensing Domain
LQT2
Pharmacologically significant constituents collectively responsible for anti-sepsis action of XueBiJing, a Chinese herb-based intravenous formulation
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 16
作者:
Cheng, Chen
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/02/27
Traditional Chinese medicine
XueBiJing
sepsis
mortality
pharmacokinetic compatibility
polypharmacology
Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies
期刊论文
OAI收割
CELL, 2024, 卷号: 187, 期号: 1, 页码: 49
作者:
Liu, Qian
;
Zhang, Jing
;
Guo, Chenchen
;
Wang, Mengcheng
;
Wang, Chenfei
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
SGF29 nuclear condensates reinforce cellular aging
期刊论文
OAI收割
CELL DISCOVERY, 2023, 卷号: 9, 期号: 1, 页码: 21
作者:
Yan, Kaowen
;
Ji, Qianzhao
;
Zhao, Dongxin
;
Li, Mingheng
;
Sun, Xiaoyan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/12/11