中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [49]
采集方式
OAI收割 [49]
内容类型
期刊论文 [49]
发表日期
2023 [3]
2021 [4]
2020 [3]
2019 [2]
2018 [2]
2015 [1]
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学科主题
Chemistry [2]
Physics [2]
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专题:上海药物研究所
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Selective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 7069
作者:
Zhou, Lin-Lin
;
Zhang, Tao
;
Xue, Yun
;
Yue, Chuan
;
Pan, Yihui
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/03/27
Design, synthesis, and STING-agonistic activity of benzo[
b
]thiophene-2-carboxamide derivatives
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2023, 页码: 10
作者:
Zhou, Rongyao
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08
STING
CDN
Benzo[b]thiophene-2-carboxamide
Cellular activity
Identification of 3H-benzo[b] [1,4] diazepine derivatives as PPAR alpha agonists by in silico studies and biochemical evaluation
期刊论文
OAI收割
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2023, 页码: 16
作者:
Li, Yue
;
Lv, Mengjia
;
Shen, Meiling
;
Gu, Xi
;
Zhang, Li
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
NAFLD
PPAR alpha agonist
virtual screening
biochemical evaluation
Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation
期刊论文
OAI收割
JOURNAL OF ADVANCED RESEARCH, 2021, 卷号: 33, 页码: 241-251
作者:
Li, Heng
;
Zhang, Xianglei
;
Xiang, Caigui
;
Feng, Chunlan
;
Fan, Chen
  |  
收藏
  |  
浏览/下载:112/0
  |  
提交时间:2021/11/04
PDE4
Arctigenin
Psoriasis
Inflammation
Interfacial interactions and structures of protic ionic liquids on a graphite surface: A first-principles study and comparison with aprotic ionic liquids
期刊论文
OAI收割
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 页码: 11
作者:
Lu, Yunxiang
;
Xu, Yanmin
;
Lu, Ling
;
Xu, Zhijian
;
Liu, Honglai
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2021/11/04
Acidity-Activatable Dynamic Nanoparticles Boosting Ferroptotic Cell Death for Immunotherapy of Cancer
期刊论文
OAI收割
ADVANCED MATERIALS, 2021, 卷号: 33, 期号: 31, 页码: 2101155
作者:
Song, Rundi
;
Li, Tianliang
;
Ye, Jiayi
;
Sun, Fang
;
Hou, Bo
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/03/21
cancer immunotherapy
ferroptosis
immune resistance
immunogenic cell death
T lymphocytes
Molecular Dynamics Simulations Reveal the Modulated Mechanism of STING Conformation
期刊论文
OAI收割
INTERDISCIPLINARY SCIENCES-COMPUTATIONAL LIFE SCIENCES, 2021, 页码: 15
作者:
Chen, Li
;
Zhao, Shuang
;
Zhu, Yanyan
;
Liu, Yongsheng
;
Li, Huiyu
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/08/17
STING
Small molecule
Binding site
Modulated mechanism
Molecular dynamics simulation
pi-pi stacking interaction
Structural Insight into the Interactions between Structurally Similar Inhibitors and SIRT6
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 7, 页码: 15
作者:
Zhao, Shuang
;
Zhu, Yan-Yan
;
Wang, Xiao-Yu
;
Liu, Yong-Sheng
;
Sun, Yun-Xiang
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
SIRT6
inhibitor
nature molecule
molecular dynamics simulation
scutellarin
hydrophobic interactions
pi-stacking interactions
binding sites
Synthesis of triazolotriazine derivatives as c-Met inhibitors
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2020, 页码: 8
作者:
Guo, Yuting
;
Peng, Xia
;
Ji, Yinchun
;
Zhang, Yitong
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/12/24
Receptor tyrosine kinase
c-Met
Triazolotriazine
SAR
Cellular potency
On-Line Electrokinetic Supercharging and Sweeping for the Preconcentration and Determination of Nucleosides and Related Compounds by Capillary Electrophoresis
期刊论文
OAI收割
ANALYTICAL LETTERS, 2020, 页码: 13
作者:
Li, Wenjia
;
Qian, Zhengming
;
Li, Chunhong
;
Guo, Dean
;
Wei, Jiangchun
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
Chinese cordyceps
electrokinetic supercharging
micellar electrokinetic chromatography
nucleobases
nucleosides
sweeping