中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [24]
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期刊论文 [73]
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Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025
作者:
Cheng, Jing
;
Yan, Ziqin
;
Jiang, Kailong
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/02/19
Development of a novel
18
F-labeled small molecule probe for PET imaging of mesenchymal epithelial transition receptor expression
期刊论文
OAI收割
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2023, 页码: 13
作者:
Bu, Lihong
;
Ma, Xiaowei
;
Ji, Aiyan
;
Geng, Kaijun
;
Feng, Hongyan
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/19
Mesenchymal epithelial transition receptor
Gliomas
[18F]-AZC
PET
Quinoline derivative compound
Insights into the fatty acid binding protein of Pacific white shrimp (Litopenaeus vannamei) suffering acute hepatopancreatic necrosis disease infection
期刊论文
OAI收割
AQUACULTURE, 2023, 卷号: 574, 页码: 12
作者:
Gu, Xiaoqian
;
Wang, Baojie
;
Jiang, Keyong
;
Liu, Mei
;
Wang, Lei
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/07
Fatty acid binding protein
AHPND
Immunofluorescence localization
Blocking assay
Neutralization assay
Transcriptome analysis
Ginkgolic acids inhibit SARS-CoV-2 and its variants by blocking the spike protein/ACE2 interplay
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2023, 卷号: 226, 页码: 780-792
作者:
Xiang, Yusen
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/04/10
SARS-CoV-2
S-RBD
Ginkgolic acid
Discovery of a selective and covalent small-molecule inhibitor of BFL-1 protein that induces robust apoptosis in cancer cells
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 236, 页码: 114327
作者:
Feng, Xuexin
;
Yan, Ziqin
;
Zhou, Feilong
;
Lou, Jianfeng
;
Lyu, Xilin
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/03/21
BFL-1
Apoptosis
Covalent inhibitor
Cytochrome c
BCL-2
Protein-Protein interaction
Ribonucleotide reductase holoenzyme inhibitor COH29 interacts with deubiquitinase ubiquitin-specific protease 2 and downregulates its substrate protein cyclin D1
期刊论文
OAI收割
FASEB JOURNAL, 2022, 卷号: 36, 期号: 5, 页码: 21
作者:
Zhu, Mengying
;
Wang, Hui
;
Ding, Yiluan
;
Yang, Yuanyuan
;
Xu, Zhuo
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2022/06/15
COH29
cyclin D1
deubiquitinase
inhibitor
USP2
Self-developed NF-kappa B inhibitor 270 protects against LPS-induced acute kidney injury and lung injury through improving inflammation
期刊论文
OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2022, 卷号: 147, 页码: 12
作者:
Yu, Yan-yan
;
Li, Xiang-qian
;
Hu, Wen-peng
;
Cu, Shi-chao
;
Dai, Jia-jia
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/06/15
AKI
ALI
Inflammation
NF-kappa B inhibitor 270
Structure-Based Virtual Screening and Identification of Potential Inhibitors of SARS-CoV-2 S-RBD and ACE2 Interaction
期刊论文
OAI收割
FRONTIERS IN CHEMISTRY, 2021, 卷号: 9, 页码: 12
作者:
Xiong, Jiacheng
;
Xiang, Yusen
;
Huang, Ziming
;
Liu, Xiaohong
;
Wang, Mengge
  |  
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/12/01
SARS-CoV-2
angiotensin-converting enzyme 2 (ACE2)
spike protein receptor-binding domain (S-RBD)
structure-based virtual screening
protein-protein interaction (PPI) inhibitors
Label-free SERS detection of Raman-Inactive protein biomarkers by Raman reporter indicator: Toward ultrasensitivity and universality
期刊论文
OAI收割
BIOSENSORS & BIOELECTRONICS, 2021, 卷号: 174, 页码: 112825
作者:
Arabi, Maryam
;
Ostovan, Abbas
;
Zhang, Zhiyang
;
Wang, Yunqing
;
Mei, Rongchao
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/12/01
Surface-enhanced Raman scattering
Raman reporter indicator mechanism
Capillary sensor
Mussel-inspired molecular imprinting
Bioassay
Genistein inhibits radiation-induced invasion and migration of glioblastoma cells by blocking the DNA-PKcs/Akt2/Rac1 signaling pathway
期刊论文
OAI收割
RADIOTHERAPY AND ONCOLOGY, 2021, 卷号: 155, 页码: 93-104
作者:
Liu, Xiongxiong
;
Wang, Qiqi
;
Liu, Bingtao
;
Zheng, Xiaogang
;
Li, Ping
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/12/10
Glioblastoma multiforme
DNA-PKcs/Akt2/Rac1 signaling
Genistein
Radiation
Invasion and migration