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Nanobodies as negative allosteric modulators for human calcium sensing receptor
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 695, 页码: 9
作者:
Cui, Qianqian
;
Wang, Lu
;
Wang, Haonan
;
Chen, Xiaochen
;
Han, Li
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/04/09
G-protein-coupled receptor
Extracellular calcium sensing receptor
Nanobody
Cryo-electron microscope
Systemic Ca 2+homoeostasis
Discovery of a brain-permeable bromodomain and extra terminal domain (BET) inhibitor with selectivity for BD1 for the treatment of multiple sclerosis
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 14
作者:
Chen, Xuetao
;
Wu, Tingting
;
Du, Zhiyan
;
Kang, Wenjing
;
Xu, Rujun
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/02/27
BET
BD1
Bromodomain
Brain-permeable
Multiple sclerosis
An LQT2-related mutation in the voltage-sensing domain is involved in switching the gating polarity of hERG
期刊论文
OAI收割
BMC BIOLOGY, 2024, 卷号: 22, 期号: 1, 页码: 14
作者:
Liu, Zhipei
;
Wang, Feng
;
Yuan, Hui
;
Tian, Fuyun
;
Yang, Chuanyan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/13
hERG
K525N
Gating Polarity
Voltage-Sensing Domain
LQT2
How does the heterogeneous interface influence hydraulic fracturing?
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF ENGINEERING SCIENCE, 2024, 卷号: 195, 页码: 31
作者:
Wang, Quan
;
Yu, Hao
;
Xu, Wenlong
;
Huang, Hanwei
;
Li, Fanding
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/02/19
Fluid -solid interaction
Hydraulic fracture
Asymptotic analysis
Heterogeneous interface
Fluid lag
Multiscale tip solution
JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
OAI收割
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
Paralichthys olivaceus
MLKL-mediated necroptosis is activated by RIPK1/3 and involved in anti-microbial immunity
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2024, 卷号: 15, 页码: 11
作者:
Hao, Kangwei
;
Xu, Hang
;
Jiang, Shuai
;
Sun, Li
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/04/07
Paralichthys olivaceus
necroptosis
RIPK1
RIPK3
MLKL
immune defense
Pantograph-Catenary Interaction Prediction Model Based on SCSA-RBF Network
期刊论文
OAI收割
APPLIED SCIENCES-BASEL, 2024, 卷号: 14, 期号: 1, 页码: 11
作者:
Wu, Mengzhen
;
Xu XH(许向红)
;
Zhang HC(张颢辰)
;
Zhou R(周睿)
;
Wang, Jianshan
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/02/19
pantograph-catenary interaction prediction model
pantograph-catenary contact force
SCSA-RBF network
Structural framework for the understanding spectroscopic and functional signatures of the cyanobacterial Orange Carotenoid Protein families
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 卷号: 254, 页码: 20
作者:
Sluchanko, Nikolai N.
;
Maksimov, Eugene G.
;
Slonimskiy, Yury B.
;
Varfolomeeva, Larisa A.
;
Bukhanko, Antonina Y.
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/01/26
Photoprotection
Phycobilisome fluorescence quenching
Crystal structure
Protein-protein interaction
Absorption spectroscopy
Photoactivity
SEC-MALS
Magmatic-hydrothermal evolution and Nb-Ta mineralization process of the Kelumute No. 112 albite-spodumene pegmatite, Altai, Xinjiang: Insights from mica compositional variation
期刊论文
OAI收割
ACTA PETROLOGICA SINICA, 2023, 卷号: 39, 期号: 11, 页码: 3369-3391
作者:
Luo YaoQing
;
Feng HaoXuan
;
Shen Ping
;
Menuge, Julian Francis
;
Bai YingXiong
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/01/02
Magmatic-hydrothermal evolution
Nb-Ta mineralization
Albite-spodumene pegmatite
Kelumute
Altai
Measurement of Ultra-High-Energy Diffuse Gamma-Ray Emission of the Galactic Plane from 10 TeV to 1 PeV with LHAASO-KM2A
期刊论文
OAI收割
PHYSICAL REVIEW LETTERS, 2023, 卷号: 131, 期号: 15
作者:
Cao, Zhen
;
Aharonian, F.
;
An, Q.
;
Axikegu
;
Bai, Y. X.
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/03/29