中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [30]
合肥物质科学研究院 [11]
上海生物化学与细胞生... [9]
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期刊论文 [64]
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浏览/检索结果:
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Discovery of HCD3514 as a potent EGFR inhibitor against C797S mutation in vitro and in vivo
期刊论文
OAI收割
JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 1, 页码: 152-162
作者:
Lai, Mengzhen
;
Zhang, Tao
;
Chen, Hao
;
Song, Peiran
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2023/04/10
fourth-generation EGFR inhibitor
EGFRC797S mutation
NSCLC
drug resistance
small molecular inhibitor
The effect of EGFR-TKIs on survival in advanced non-small-cell lung cancer with EGFR mutations: A real-world study
期刊论文
OAI收割
CANCER MEDICINE, 2022
作者:
Yu, Xiaoqing
;
Si, Jinfei
;
Wei, Jingwen
;
Wang, Yanling
;
Sun, Yan
  |  
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2022/12/23
EGFR-TKIs
non-small cell lung cancer (NSCLC)
real-world study
survival outcome
The reversal of anti-HER2 resistance in advanced HER2-positive breast cancer using apatinib: two cases reports and literature review
期刊论文
OAI收割
TRANSLATIONAL CANCER RESEARCH, 2022
作者:
He, Libin
;
Shen, Xiabo
;
Liu, Yiyuan
;
Gao, Lu
;
Wu, Jiayi
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/12/23
Advanced human epidermal growth factor receptor 2-positive breast cancer (advanced HER2-positive breast cancer)
apatinib
case report
Baseline anemia predicts a poor prognosis in patients with non-small cell lung cancer with epidermal growth factor receptor mutations: a retrospective study
期刊论文
OAI收割
BMC PULMONARY MEDICINE, 2022, 卷号: 22
作者:
Wei, Jingwen
;
Xiang, Jing
;
Hao, Yue
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/12/22
Anemia
Epidermal growth factor receptor
Epidermal growth factor receptor tyrosine kinase inhibitors
Non-small cell lung cancer
Drug-resistant HER2-positive breast cancer: Molecular mechanisms and overcoming strategies
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:
Wu, Xiaofan
;
Yang, Hongjian
;
Yu, Xingfei
;
Qin, Jiang-Jiang
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/12/22
HER2
breast cancer
targeted therapy
drug resistance
overcoming strategies
Design, synthesis and evaluation of the Brigatinib analogues as potent inhibitors against tertiary EGFR mutants (EGFR(del19/T790M/C797S) and EGFR(L858R/T790M/C797S))
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022, 卷号: 72, 页码: 11
作者:
Fang, Haotian
;
Wu, Yingming
;
Xiao, Qitao
;
He, Dongbo
;
Zhou, Tongrui
  |  
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2022/08/16
Non-small cell lung cancer
EGFR
Triple mutations
C797S
EGFR-TKIs
Dual-responsive nanoparticles loading bevacizumab and gefitinib for molecular targeted therapy against non-small cell lung cancer
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 11
作者:
Zhao, Zi-tong
;
Wang, Jue
;
Fang, Lei
;
Qian, Xin-di
;
Cai, Ying
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/08/16
nanoparticles
molecular targeted therapy
non-small cell lung cancer
dual-responsive
controlled release
Clinical outcomes of lung adenocarcinoma patients harboring uncommon epidermal growth factor receptor (EGFR) mutations treated with EGFR-tyrosine kinase inhibitors (TKIs)
期刊论文
OAI收割
ANNALS OF PALLIATIVE MEDICINE, 2021
作者:
Si, Jinfei
;
Gu, Xiaodong
;
Wang, Wenxian
;
Ying, Shenpeng
;
Song, Zhengbo
  |  
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2022/02/14
Epidermal growth factor receptor (EGFR)
uncommon mutation
compound mutation
double uncommon mutation
lung adenocarcinoma (lung AC)
The correlation between the abundance of EGFR T790M mutation and osimertinib response in advanced non-small cell lung cancer
期刊论文
OAI收割
TRANSLATIONAL CANCER RESEARCH, 2021, 卷号: 10
作者:
Pan, Guoqiang
;
Chen, Kaiyan
;
Yu, Xiaoqing
;
Sheng, Jiamin
;
Fan, Yun
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2021/11/01
Non-small cell lung cancer (NSCLC)
T790M abundance
droplet digital PCR (ddPCR)
next generation sequencing (NGS)
osimertinib
Immune microenvironment features and efficacy of PD-1/PD-L1 blockade in non-small cell lung cancer patients with EGFR or HER2 exon 20 insertions
期刊论文
OAI收割
THORACIC CANCER, 2020
作者:
Chen, Kaiyan
;
Pan, Guoqiang
;
Cheng, Guoping
;
Zhang, Fanrong
;
Xu, Yanjun
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2020/12/28
EGFR
HER2
immunotherapy
NSCLC
PD‐
L1