机构

• 上海药物研究所 [6]
• 化学研究所 [2]
• 青岛生物能源与过程研... [2]
• 上海生物化学与细胞生... [2]
• 上海营养与健康研究所 [2]
• 长春光学精密机械与物... [1]
• 更多

采集方式

• OAI收割 [22]

内容类型

• 期刊论文 [21]
• 学位论文 [1]

发表日期

• 2023 [1]
• 2022 [2]
• 2021 [1]
• 2020 [2]
• 2019 [4]
• 2018 [4]
• 更多

学科主题

• Cell Biolo... [2]
• 生物催化与转化::生... [2]
• Biochemist... [1]
• Developmen... [1]
• Fisheries [1]
• Immunology [1]
• 更多

筛选

浏览/检索结果: 共22条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of HCD3514 as a potent EGFR inhibitor against C797S mutation in vitro and in vivo 期刊论文  OAI收割 JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 1, 页码: 152-162 作者:  Lai, Mengzhen;  Zhang, Tao;  Chen, Hao;  Song, Peiran;  Tong, Linjiang   |  收藏  |  浏览/下载：80/0  |  提交时间：2023/04/10 fourth-generation EGFR inhibitor  EGFRC797S mutation  NSCLC  drug resistance  small molecular inhibitor   Design, synthesis and evaluation of the Brigatinib analogues as potent inhibitors against tertiary EGFR mutants (EGFR(del19/T790M/C797S) and EGFR(L858R/T790M/C797S)) 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022, 卷号: 72, 页码: 11 作者:  Fang, Haotian;  Wu, Yingming;  Xiao, Qitao;  He, Dongbo;  Zhou, Tongrui   |  收藏  |  浏览/下载：73/0  |  提交时间：2022/08/16 Non-small cell lung cancer  EGFR  Triple mutations  C797S  EGFR-TKIs   Design, Synthesis, and Biological Evaluation of Novel EGFR PROTACs Targeting Del19/T790M/C797S Mutation 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2022, 卷号: 13, 期号: 2, 页码: 278-283 作者:  Zhang, Hualin;  Xie, Ruliang;  AI-furas, Hawaa;  Li, Yupeng;  Wu, Qingxia   |  收藏  |  浏览/下载：26/0  |  提交时间：2022/06/15 NSCLC  acquired resistance  EGFR C797S  PROTACs  selectivity   LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文  OAI收割 CANCER SCIENCE, 2021, 页码: 12 作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan;  Wang, Yanan;  Feng, Fang   |  收藏  |  浏览/下载：87/0  |  提交时间：2022/01/18 C797S  epidermal growth factor receptor  fourth-generation EGFR TKI  non-small cell lung cancer  osimertinib resistance   Dosage effect of multiple genes accounts for multisystem disorder of myotonic dystrophy type 1 期刊论文  OAI收割 CELL RESEARCH, 2020, 卷号: 30, 期号: 2, 页码: 133-145 作者:  Yin, Qi;  Li, Na;  Ding, Yifu;  Xie, Zhenfei;  Jin, Lifang   |  收藏  |  浏览/下载：34/0  |  提交时间：2020/12/21 TRIPLET REPEAT EXPANSION  3 UNTRANSLATED REGION  CTG REPEAT  SATELLITE CELLS  MESSENGER-RNA  MYOGENIC DIFFERENTIATION  TRINUCLEOTIDE REPEAT  CHROMATIN-STRUCTURE  REDUCES EXPRESSION  MODIFIED MICE   Aedes aegypti carrying triple knockdown resistance mutations in Beijing, China 期刊论文  OAI收割 LANCET INFECTIOUS DISEASES, 2020, 卷号: 20, 期号: 2 作者:  Qiu XH(邱星辉);  Liu Nian;  Yang Chan;  Zhou Xiaojie   |  收藏  |  浏览/下载：6/0  |  提交时间：2021/10/26 Morphology of Osteogenesis Imperfecta Collagen Mimetic Peptide Assemblies Correlates with the Identity of Glycine-Substituting Residue 期刊论文  OAI收割 CHEMBIOCHEM, 2019, 页码: 8 作者:  Yao, Linyan;  Liu, Zhao;  Yu, Jingyuan;  Luo, Liting;  Wang, Jie   |  收藏  |  浏览/下载：66/0  |  提交时间：2020/01/14 collagen mimetic peptides  morphology  mutations  osteogenesis imperfecta  triple helices   Structure-Based Design of 5-Methylpyrimidopyridone Derivatives as New Wild-Type Sparing Inhibitors of the Epidermal Growth Factor Receptor Triple Mutant (EGFR(L858R/T790M/C797S)) 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 15, 页码: 7302-7308 作者:  Shen, Jiayi;  Zhang, Tao;  Zhu, Su-Jie;  Sun, Min;  Tong, Linjiang   |  收藏  |  浏览/下载：37/0  |  提交时间：2020/07/01 Genomic and Transcriptomic Landscape of Triple-Negative Breast Cancers: Subtypes and Treatment Strategies 期刊论文  OAI收割 CANCER CELL, 2019, 卷号: 35, 期号: 3, 页码: 428-+ 作者:  Jiang, Yi-Zhou;  Ma, Ding;  Hu, Xin;  Xiao, Yi;  Yu, Ke-Da   |  收藏  |  浏览/下载：48/0  |  提交时间：2020/12/09 EGFR-specific CAR-T cells trigger cell lysis in EGFR-positive TNBC 期刊论文  OAI收割 Aging-Us, 2019, 卷号: 11, 期号: 23, 页码: 11054-11072 作者:  Y.Liu;  Y.H.Zhou;  K.H.Huang;  Y.Li;  X.J.Fang   |  收藏  |  浏览/下载：44/0  |  提交时间：2020/08/24 triple-negative breast cancer,human epidermal growth factor receptor,chimeric antigen receptor engineered T cells,negative breast-cancer,growth-factor receptor,therapy,amplification,inhibition,expression,challenges,mutations,her2,Cell Biology,Geriatrics & Gerontology