中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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The Effects of Topiramate on Ethanol-Cocaine Interactions andDNA Methyltransferase Gene Expression in the Rat Prefrontal Cortex
期刊论文
OAI收割
出版物, 3111, 期号: 0, 页码: 1-39
作者:
V.Echeverry-Alzate
;
E. Gine
;
K. M. Bühler
;
J. Calleja-Conde
;
P. Olmos
  |  
收藏
  |  
浏览/下载:327/0
  |  
提交时间:2017/07/24
Operant Ethanol Self-administration
Dnmt1 Corepressors
Histone deacetylase-2
Dual Dependence
Dna Methyltransferases
Addiction
Gene Expression
Zinc finger protein ZNF638 regulates triglyceride metabolism via ANGPTL8 in an estrogen dependent manner
期刊论文
OAI收割
METABOLISM-CLINICAL AND EXPERIMENTAL, 2024, 卷号: 152, 页码: 12
作者:
Meng, Meiyao
;
Cao, Yuxiang
;
Qiu, Jin
;
Shan, Guangyu
;
Wang, Yingwen
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/03/25
Triglyceride metabolism
ZNF638
Adipose tissue
Angptl8
Lipoprotein lipase
Proteomics analysis of histone deacetylase inhibitor-resistant solid tumors reveals resistant signatures and potential drug combinations
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11
作者:
Hao, Bing-bing
;
Ma, Ke
;
Xu, Jun-yu
;
Fan, Ru-feng
;
Zhao, Wen-si
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/03/25
solid tumor
histone deacetylase inhibitor
vorinostat (SAHA)
drug resistance
proteomics
Targeting JMJD1C to selectively disrupt tumor T
reg
cell fitness enhances antitumor immunity
期刊论文
OAI收割
NATURE IMMUNOLOGY, 2024, 页码: 32
作者:
Long, Xuehui
;
Zhang, Sulin
;
Wang, Yuliang
;
Chen, Jingjing
;
Lu, Yanlai
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/25
A proteomic landscape of pharmacologic perturbations for functional relevance
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2024, 卷号: 14, 期号: 1, 页码: 128-139
作者:
Liu, Zhiwei
;
Jiang, Shangwen
;
Hao, Bingbing
;
Xie, Shuyu
;
Liu, Yingluo
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/04/09
Proteomics
Drug
Perturbation
Drug target
Drug combination
Epigenetic-based combination therapy and liposomal codelivery overcomes osimertinib-resistant NSCLC via repolarizing tumor-associated macrophages
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Lin, Ting-ting
;
Xiong, Wei
;
Chen, Gui-hua
;
He, Yang
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/01/26
osimertinib resistance
targeted drug delivery
liposomes
panobinostat
tumor-associated macrophage
combination therapy
Ascorbic Acid Reprograms Epigenome and Epitranscriptome by Reducing Fe(III) in the Catalytic Cycle of Dioxygenases
期刊论文
OAI收割
ACS CHEMICAL BIOLOGY, 2023, 卷号: 19, 期号: 1, 页码: 129-140
作者:
He, Weizhi
;
Yin, Xiaotong
;
Xu, Chu
;
Liu, Xiangyue
;
Huang, Yue
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
NIR-II fluorescence-guided liver cancer surgery by a small molecular HDAC6 targeting probe
期刊论文
OAI收割
EBIOMEDICINE, 2023, 卷号: 98, 页码: 18
作者:
Wang, Bo
;
Tang, Chu
;
Lin, En
;
Jia, Xiaohua
;
Xie, Ganyuan
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/02/22
Hepatocellular carcinoma
Second near-infrared window
Molecular imaging
HDAC6
Fluorescence guided surgery
HDAC3 and HDAC8 PROTAC dual degrader reveals roles of histone acetylation in gene regulation
期刊论文
OAI收割
CELL CHEMICAL BIOLOGY, 2023, 卷号: 30, 期号: 11, 页码: 1421-+
作者:
Xiao, Yufeng
;
Hale, Seth
;
Awasthee, Nikee
;
Meng, Chengcheng
;
Zhang, Xuan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/16
Discovery, Structure-Activity Relationship and In Vitro Anticancer Activity of Small-Molecule Inhibitors of the Protein-Protein Interactions between AF9/ENL and AF4 or DOT1L
期刊论文
OAI收割
CANCERS, 2023, 卷号: 15, 期号: 21, 页码: 28
作者:
Li, Xin
;
Wu, Xiaowei
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/19
MLL-rearranged leukemia
super elongation complexes
small-molecule inhibitor
protein-protein interaction
cancer therapeutics