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浏览/检索结果: 共84条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Privileged heterocycles for DNA-encoded library design and hit-to-lead optimization 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 26 作者:  Wen, Xin;  Wu, Xinyuan;  Jin, Rui;  Lu, Xiaojie   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/04/10 DNA Encoded library  Drug discovery  Heterocycles  Hit identification  Lead generation   Discovery of Potent Small-Molecule USP8 Inhibitors for the Treatment of Breast Cancer through Regulating ERα Expression 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 13, 页码: 8914-8932 作者:  Tian, Yucheng;  Liu, Kang;  Liu, Ruoyi;  Qiu, Zhixia;  Xu, Yifan   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/03/21 Identification of PRMT5 inhibitors with novel scaffold structures through virtual screening and biological evaluations 期刊论文  OAI收割 JOURNAL OF MOLECULAR MODELING, 2022, 卷号: 28, 期号: 7, 页码: 184 作者:  Zhang, Qian;  Zhang, Lun;  Jin, Jia;  Fan, Yaohua;  Wang, Xiaoguang   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/03/21 PRMT5  Small-molecule inhibitors  Virtual screening  Molecular docking  Molecular dynamics simulations   Discovery of a selective and covalent small-molecule inhibitor of BFL-1 protein that induces robust apoptosis in cancer cells 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 236, 页码: 114327 作者:  Feng, Xuexin;  Yan, Ziqin;  Zhou, Feilong;  Lou, Jianfeng;  Lyu, Xilin   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/03/21 BFL-1  Apoptosis  Covalent inhibitor  Cytochrome c  BCL-2  Protein-Protein interaction   DNA-encoded focused indazole library synthesis by a palladium- mediated C-N(sp(2)) cross-coupling reaction between DNA-linked (hetero)aryl halides and aromatic nitrogen heterocycles 期刊论文  OAI收割 TETRAHEDRON LETTERS, 2022, 卷号: 96, 页码: 6 作者:  Yang, Juan;  Xia, Shengdi;  Liu, Jiaxiang;  Yu, Zikun;  Mei, Lianghe   |  收藏  |  浏览/下载：23/0  |  提交时间：2022/08/16 D3AI-CoV: a deep learning platform for predicting drug targets and for virtual screening against COVID-19 期刊论文  OAI收割 BRIEFINGS IN BIOINFORMATICS, 2022, 页码: 16 作者:  Yang, Yanqing;  Zhou, Deshan;  Zhang, Xinben;  Shi, Yulong;  Han, Jiaxin   |  收藏  |  浏览/下载：35/0  |  提交时间：2022/06/15 D3AI-CoV  COVID-19  deep learning  target prediction  virtual screening   Phosphodiesters as GPR84 Antagonists for the Treatment of Ulcerative Colitis 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 5, 页码: 3991-4006 作者:  Chen, Lin-Hai;  Zhang, Qing;  Xiao, Yu-Feng;  Fang, You-Chen;  Xie, Xin   |  收藏  |  浏览/下载：21/0  |  提交时间：2022/06/15 Identification, Synthesis, and Biological Evaluations of Potent Inhibitors Targeting Type I Protein Arginine Methyltransferases 期刊论文  OAI收割 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2022, 卷号: 62, 期号: 3, 页码: 692-702 作者:  Li, Xiao;  Zhang, Lun;  Xu, Jing;  Liu, Chenyu;  Zhang, Xiaojian   |  收藏  |  浏览/下载：19/0  |  提交时间：2022/06/15 Double-hit separation and dE/dx resolution of a time projection chamber with GEM readout 期刊论文  OAI收割 Journal of Instrumentation, 2022, 卷号: 17, 期号: 11, 页码: 11027 作者:  LCTPC Collaboration   |  收藏  |  浏览/下载：3/0  |  提交时间：2023/11/09 Identification and Investigation of the Genetic Variations and Candidate Genes Responsible for Seed Weight via GWAS in Paper Mulberry 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 卷号: 23, 期号: 20 作者:  Hu, Yanmin;  Peng, Xianjun;  Shen, Shihua   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/03/07 genome-wide association study  seed weight  woody plant  genetic variation  candidate gene  fatty acid desaturase