中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [28]
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中国科学院大学 [2]
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期刊论文 [41]
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Discovery and Optimization of WDR5 Inhibitors via Cascade Deoxyribonucleic Acid-Encoded Library Selection Approach
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1079-1092
作者:
Qin, Shaozhao
;
Feng, Lijian
;
Zhao, Qingyi
;
Yan, Ziqin
;
Lyu, Xilin
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/02/27
ABPP-CoDEL: Activity-Based Proteome Profiling-Guided Discovery of Tyrosine-Targeting Covalent Inhibitors from DNA-Encoded Libraries
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2023, 卷号: 145, 期号: 46, 页码: 25283-25292
作者:
Jiang, Lulu
;
Liu, Sixiu
;
Jia, Xinglong
;
Gong, Qinting
;
Wen, Xin
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/01/16
Discovery, SAR Study of GST Inhibitors from a Novel Quinazolin-4(1H)-one Focused DNA-Encoded Library
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 15
作者:
Wen, Xin
;
Zhang, Minmin
;
Duan, Zhiqiang
;
Suo, Yanrui
;
Lu, Weiwei
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2023/10/17
Design, Construction, and Screening of Diversified Pyrimidine-Focused DNA-Encoded Libraries
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 14, 期号: 8, 页码: 1073-1078
作者:
Seydimemet, Mengnisa
;
Yang, Yixuan
;
Lv, Yuhan
;
Liu, Jiaxiang
;
Yan, Ziqin
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
DNA-encoded library technology
Pyrimidine-focusedDNA-encodedlibrary
BRD4
Affinity screening
Inhibitor
The Development of DNA-Compatible S-Glycosyl Transformations
期刊论文
OAI收割
ORGANIC LETTERS, 2023, 卷号: 25, 期号: 26, 页码: 4940-4944
作者:
Zhao, Qingyi
;
Bao, Yandan
;
Niu, Dawen
;
Wang, Xuan
;
Lu, Xiaojie
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Modular Click Assembly DNA-Encoded Glycoconjugate Libraries with on-DNA Functional Group Transformations
期刊论文
OAI收割
BIOCONJUGATE CHEMISTRY, 2023, 卷号: 34, 期号: 4, 页码: 616-620
作者:
Ling, Xing
;
Liu, Sixiu
;
Yang, Yixuan
;
Dong, Qian
;
Marcaurelle, Lisa A.
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/03/27
Privileged heterocycles for DNA-encoded library design and hit-to-lead optimization
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 26
作者:
Wen, Xin
;
Wu, Xinyuan
;
Jin, Rui
;
Lu, Xiaojie
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/04/10
DNA Encoded library
Drug discovery
Heterocycles
Hit identification
Lead generation
Ruthenium-Mediated [2+2+2] Cyclization: A Route to Forge Indane and Isoindoline Core and Its Application in DNA-Encoded Library Technology
期刊论文
OAI收割
ORGANIC LETTERS, 2022, 页码: 5
作者:
Suo, Yanrui
;
Xu, Min
;
Sun, Meimei
;
Lu, Weiwei
;
Wang, Xuan
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/04/10
Quantitative Validation and Application of the Photo-Cross-Linking Selection for Double-Stranded DNA-Encoded Libraries
期刊论文
OAI收割
BIOCONJUGATE CHEMISTRY, 2022, 页码: 7
作者:
Wu, Xinyuan
;
Chen, Yujie
;
Lu, Weiwei
;
Jin, Rui
;
Lu, Xiaojie
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/11/11
Triazine-Based Covalent DNA-Encoded Libraries for Discovery of Covalent Inhibitors of Target Proteins
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2022, 页码: 8
作者:
Li, Linjie
;
Su, Mingbo
;
Lu, Weiwei
;
Song, Hongzhi
;
Liu, Jiaxiang
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/09/30
DNA encoded library
covalent library
library design
covalent inhibitors