机构

• 上海药物研究所 [3]
• 昆明植物研究所 [1]
• 上海营养与健康研究所 [1]
• 合肥物质科学研究院 [1]

采集方式

• OAI收割 [6]

内容类型

• 期刊论文 [6]

发表日期

• 2024 [1]
• 2022 [1]
• 2021 [1]
• 2020 [1]
• 2019 [1]
• 2015 [1]
• 更多

学科主题

• Oncology; ... [1]
• Pharmacolo... [1]

筛选

浏览/检索结果: 共6条，第1-6条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Structure-based development of potent and selective type-II kinase inhibitors of RIPK1 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334 作者:  Qin, Ying;  Li, Dekang;  Qi, Chunting;  Xiang, Huaijiang;  Meng, Huyan   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/03/06 RIPK1  Necroptosis  Type-II kinase inhibitors  Rational design  Lead optimization  Structure-activity relationship  Anti-inflammation  Preclinical drug discovery   Repurposing of the FGFR inhibitor AZD4547 as a potent inhibitor of necroptosis by selectively targeting RIPK1 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022 作者:  Wang, Zuo-wei;  Zou, Feng-ming;  Wang, Ao-li;  Yang, Jing;  Jin, Rui   |  收藏  |  浏览/下载：30/0  |  提交时间：2022/12/22 AZD4547  RIPK1  inhibitors  SIRS model  anti-necroptosis   Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 6 作者:  Yang, Xiangbo;  Lu, Huimin;  Xie, Hang;  Zhang, Binbin;  Nie, Tianqing   |  收藏  |  浏览/下载：28/0  |  提交时间：2022/01/18 Binding studies  Drug discovery  Necroptosis  RIPK1 inhibitors  Sepsis   RIPK1 inhibitor ameliorates colitis by directly maintaining intestinal barrier homeostasis and regulating following IECs-immuno crosstalk 期刊论文  OAI收割 BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 172, 页码: 16 作者:  Lu, Huimin;  Li, Heng;  Fan, Chen;  Qi, Qing;  Yan, Yuxi   |  收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01 RIPK1 inhibitor  Colitis  Barrier homeostasis  IECs-immunocytes crosstalk  Necroptosis  NF-kappa B   Identification of the Raf kinase inhibitor TAK-632 and its analogues as potent inhibitors of necroptosis by targeting RIPK1 and RIPK3 期刊论文  OAI收割 BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 12, 页码: 2095-2108 作者:  Chen, Xiaofei;  Ren, Yibin;  Qin, Xia;  Hu, Longmiao;  Fu, Jing   |  收藏  |  浏览/下载：59/0  |  提交时间：2020/12/09 Post-translational modification  myristoylation site prediction  modified glycine residue  extreme learning machine  minimum redundancy maximum relevance  incremental feature selection   Neoalbaconol induces cell death through necroptosis by regulating RIPK-dependent autocrine TNF alpha and ROS production 期刊论文  OAI收割 ONCOTARGET, 2015, 卷号: 6, 期号: 4, 页码: 1995-2008 作者:  Yu, Xinfang;  Deng, Qipan;  Li, Wei;  Xiao, Lanbo;  Luo, Xiangjian 收藏  |  浏览/下载：59/0  |  提交时间：2015/06/29 necoalbaconol  necroptosis  RIPK  TNF alpha  NF-kappa B signaling pathway  ROS