中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [12]
西北高原生物研究所 [1]
中国科学院大学 [1]
海洋研究所 [1]
上海生物化学与细胞生... [1]
合肥物质科学研究院 [1]
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OAI收割 [16]
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期刊论文 [17]
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2024 [1]
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2021 [1]
2020 [1]
2019 [2]
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Cell Biolo... [1]
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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
OAI收割
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
L-5-hydroxytryptophan promotes antitumor immunity by inhibiting PD-L1 inducible expression
期刊论文
OAI收割
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 卷号: 10, 期号: 6, 页码: 14
作者:
Huang, Jing
;
Wang, Xiaobo
;
Li, Bing
;
Shen, Shiyu
;
Wang, Ruina
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/08/16
Immunotherapy
Immune Evation
T-Lymphocytes
Translational Medical Research
Profiling Receptor Tyrosine Kinase Fusions in Chinese Breast Cancers
期刊论文
OAI收割
FRONTIERS IN ONCOLOGY, 2021, 卷号: 11
作者:
Tao, Zhonghua
;
Liu, Jianxia
;
Li, Ting
;
Xu, Hong
;
Chen, Kai
  |  
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2022/01/10
receptor tyrosine kinase
gene fusion
genomic rearrangments
breast cancer
next-generation sequencing
Synthesis and evaluation of new thiourea derivatives as antitumor and antiangiogenic agents
期刊论文
OAI收割
TETRAHEDRON LETTERS, 2020, 卷号: 61, 期号: 40
作者:
Bai, Wenjing
;
Ji, Jianxin
;
Huang, Qiang
;
Wei, Wei
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/11/25
Thiourea derivatives
Antitumor
Antiangiogenesis
RTK inhibitors
Activation and function of receptor tyrosine kinases in human clear cell renal cell carcinomas
期刊论文
OAI收割
BMC CANCER, 2019, 卷号: 19, 期号: 1, 页码: 13
作者:
Zhang, Qing
;
Liu, Jian-He
;
Liu, Jing-Li
;
Qi, Chun-Ting
;
Yan, Lei
  |  
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2020/07/01
Receptor tyrosine kinases (RTKs)
Activation and function
Clear cell renal cell carcinomas (ccRCCs)
Targeted therapy
PDGFR beta
Stroma cells
Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 15
作者:
Jin, Nan
;
Bi, Aiwei
;
Lan, Xiaojing
;
Xu, Jun
;
Wang, Xiaomin
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
Concomitant inhibition of receptor tyrosine kinases and downstream AKT synergistically inhibited growth of KRAS/BRAF mutant colorectal cancer cells
期刊论文
OAI收割
ONCOTARGET, 2017, 卷号: 8, 期号: 3, 页码: 5003-5015
作者:
Song, Qiaoling
;
Sun, Xiaoxiao
;
Guo, Hui
;
Yu, Qiang
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
receptor tyrosine kinases
AKT
colorectal cancer
drug combination
RAS/RAF
Novel metal complexes of naphthalimide-cyclam conjugates as potential multi-target receptor tyrosine kinase (RTK) inhibitors: Synthesis and biological evaluation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 85, 页码: 207-214
作者:
Tan, Shaoying
;
Han, Kun
;
Li, Qiang
;
Tong, Linjiang
;
Yang, Yiqi
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Metal complexes
Naphthalimide
Cyclam
RTK inhibitors
Antiproliferation
Antiangiogenesis
Blocking autocrine VEGF signaling by sunitinib, an anti-cancer drug, promotes embryonic stem cell self-renewal and somatic cell reprogramming
期刊论文
OAI收割
CELL RESEARCH, 2014, 卷号: 24, 期号: 9, 页码: 1121-1136
作者:
Chen, Guofang
;
Xu, Xinxiu
;
Zhang, Lihong
;
Fu, Yanbin
;
Wang, Min
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
sunitinib
Sutent
embryonic stem cell
self-renewal
iPSC
VEGF
autocrine
Novel 2,4-Diarylanninopyrimidine Analogues (DAAPalogues) Showing Potent c-Met/ALK Multikinase Inhibitory Activities
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 5, 期号: 4, 页码: 304-308
作者:
Liu, Zhiqing
;
Ai, Jing
;
Peng, Xia
;
Song, Zilan
;
Wu, Kui
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2019/01/08
C1-Substituted-N3-benzazepine
c-Met/ALK dual inhibitor
structure repurposing
2,4-diarylaminopyrimidine analogues