中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [228]
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期刊论文 [498]
学位论文 [13]
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The predictive role of early inflammation and oxidative stress and the dynamics of cytokines networks in post-stroke depression
期刊论文
OAI收割
JOURNAL OF AFFECTIVE DISORDERS, 2024, 卷号: 347, 页码: 469-476
作者:
Wen, Lulu
;
Yan, Chuming
;
Si, Tong
;
Huang, Liyuan
;
Nie, Yuting
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/22
Post stroke depression
Cytokines
Oxidative stress
Biomarker
Inflammation
A robust and validated LC-MS/MS method for the quantification of ramucirumab in rat and human serum using direct enzymatic digestion without immunoassay
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2024, 卷号: 1234, 页码: 11
作者:
Huang, Wen-si
;
Li, Wei-qiang
;
Yu, Xiong
;
Xue, Ming-zhen
;
Yuan, Ya-li
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/04/09
Anti -gastric cancer monoclonal antibody
Ramucirumab
LC -MS/MS
Method validation
Surrogate peptide
Metabolism investigation of the peptide-drug conjugate LN005 in rats using UHPLC-HRMS
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 238, 页码: 11
作者:
Wang, Weiqiang
;
Chen, Chong
;
Luo, Jing
;
Tang, Chongzhuang
;
Zheng, Yuandong
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/01/16
LN005
Metabolism
Peptide -drug conjugates
UHPLC-HRMS
Doxorubicin
Development and validation of a sensitive liquid chromatography-tandem mass spectrometry method for the assay of 12 substances in rat plasma and its application to rat pharmacokinetics of
Epimedium
and
Psoraleae Fructus
herb pair after oral administration
期刊论文
OAI收割
JOURNAL OF SEPARATION SCIENCE, 2024, 卷号: 47, 期号: 1, 页码: 17
作者:
Wang, Linwei
;
Yin, Xiaoying
;
Liu, Huan
;
Wang, Yangyang
;
Li, Zhixiong
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/02/27
compatibility behaviors
Epimedium
LC-MS/MS
pharmacokinetics
Psoraleae Fructus
Qing-Zhi-Tiao-Gan-Tang (QZTGT) prevents nonalcoholic steatohepatitis (NASH) by expression pattern correction
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 317, 页码: 14
作者:
Chu, Hang
;
Zhang, Weitao
;
Tan, Yan
;
Diao, Zhipeng
;
Li, Peng
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
Fibrosis
Inflammation
Lipogenesis
NASH
QZTGT
TMNP
Absorption, Distribution, Metabolism, and Excretion of [
14
C]BS1801, a Selenium-Containing Drug Candidate, in Rats
期刊论文
OAI收割
MOLECULES, 2023, 卷号: 28, 期号: 24, 页码: 16
作者:
Yang, Cheng
;
Xue, Mingzhen
;
He, Yifei
;
Yin, Hanwei
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/01/26
[C-14]BS1801
BS1801 (butaselen)
tissue distribution
metabolism
mass balance
selenium
Pharmacokinetic and metabolite profile of orally administered anemoside B4 in rats with an improved exposure in formulations of rectal suppository
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 315, 页码: 11
作者:
Ye, Yaqing
;
Xue, Mingzhen
;
Tian, Xiaoting
;
Gao, Hongwei
;
Hu, Pei
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Anemoside B4
Pulsatilla chinensis
metabolite identification
Pharmacokinetics
Rectal suppository
Precolumn derivatization LC-MS/MS method to simultaneous quantitation of 10 monosaccharides in rat plasma
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 卷号: 234, 页码: 10
作者:
Li, Mengxue
;
Li, Ping
;
Ji, Yuting
;
Tian, Yihua
;
Zeng, Huiying
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/10/17
LC-MS
MS
Monosaccharides
Derivatization
1-Phenyl-3-methyl-5-pyrazolone (PMP)
Biomarker
Pharmacokinetics, Mass Balance, Tissue Distribution, and Metabolism of [
3
H]Catalpol in Rats: the Main Bioactive Component of
Rehmannia glutinosa
for the Treatment of Ischemic Stroke
期刊论文
OAI收割
CURRENT DRUG METABOLISM, 2023, 页码: 10
作者:
Ge, Xinyu
;
Zheng, Yuandong
;
He, Yifei
;
Chen, Chong
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08
[H-3]catalpol
Rehmannia glutinosa
mass balance
tissue distribution
metabolism
intestinal flora
ischemic stroke.
单次延长应激诱导创伤后应激障碍共病抑郁的免疫炎性机理
学位论文
OAI收割
中国科学院心理研究所: 中国科学院大学, 2023
作者:
戴佳婕
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/10/27
单次延长应激
创伤后应激障碍
抑郁
共病
免疫炎性