中国科学院机构知识库网格系统: 检索

浏览/检索结果: 共4条，第1-4条

帮助

条数/页：排序方式：
	JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文 OAI收割 CANCER LETTERS, 2024, 卷号: 582, 页码: 15 作者: Lu, Xuxiu; Yu, Rilei; Li, Zhen; Yang, Mengke; Dai, Jiajia \| 收藏 \| 浏览/下载：13/0 \| 提交时间：2024/04/07 Acquired resistance Cancer NSCLC JC-010a SHP2
	From bench to bedside: current development and emerging trend of KRAS-targeted therapy 期刊论文 OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 18 作者: Chen, Yi; Liu, Qiu-pei; Xie, Hua; Ding, Jian \| 收藏 \| 浏览/下载：28/0 \| 提交时间：2024/01/16 KRAS mutation KRAS(G12C) inhibitor Pan-KRAS inhibitor SHP2 allosteric inhibitor SOS1 inhibitor combination therapy
	Allosteric Inhibitors of SHP2: An Updated Patent Review (2015-2020) 期刊论文 OAI收割 CURRENT MEDICINAL CHEMISTRY, 2021, 卷号: 28, 期号: 19, 页码: 3825-3842 作者: Wu, Jingwei; Zhang, Huan; Zhao, Guilong; Wang, Runling \| 收藏 \| 浏览/下载：15/0 \| 提交时间：2021/08/17 SHP2 inhibitor PTPN11 gene allosteric cancer combination therapy clinical trial
	Synthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors 期刊论文 OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 11, 页码: 5 作者: Satheeshkumar, Rajendran; Zhu, Rui; Feng, Bo; Huang, Chao; Gao, Ya \| 收藏 \| 浏览/下载：38/0 \| 提交时间：2020/07/01 Heterocyclic bis-aryl amides PTP1B SHP2 Inhibitors Structure-activity relationships (SAR)