机构

• 上海药物研究所 [5]
• 上海营养与健康研究所 [1]

采集方式

• OAI收割 [6]

内容类型

• 期刊论文 [6]

发表日期

• 2023 [1]
• 2021 [1]
• 2020 [2]
• 2018 [2]

学科主题

• Oncology [1]

筛选

浏览/检索结果: 共6条，第1-6条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of Novel SIRT1/2 Inhibitors with Effective Cytotoxicity against Human Leukemia Cells 期刊论文  OAI收割 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2023, 页码: 11 作者:  Cai, Haiyan;  Wang, Yingying;  Zhang, Jing;  Wei, Zhenquan;  Yan, Teng   |  收藏  |  浏览/下载：16/0  |  提交时间：2023/10/17 Discovery of 5-Benzylidene-2-phenyl-1,3-dioxane-4,6-diones as Highly Potent and Selective SIRT1 Inhibitors 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 3, 页码: 397-403 作者:  Li, Chunpu;  Hu, Sha-Sha;  Yang, Lisheng;  Wang, Min;  Long, Jian-Dong   |  收藏  |  浏览/下载：61/0  |  提交时间：2021/05/24 SIRT1  inhibitor  structure-activity relationship  interaction  deacetylase   Design, Synthesis, and Biological Evaluation of 8-Mercapto-3,7-Dihydro-1H-Purine-2,6-Diones as Potent Inhibitors of SIRT1, SIRT2, SIRT3, and SIRT5 期刊论文  OAI收割 MOLECULES, 2020, 卷号: 25, 期号: 12, 页码: 18 作者:  Han, Haozhen;  Li, Chunpu;  Li, Man;  Yang, Lisheng;  Zhao, Sen   |  收藏  |  浏览/下载：18/0  |  提交时间：2020/12/24 sirtuins  inhibitor  structure-activity relationship  deacetylase   Molecular dynamics simulations reveal the mechanism of the interactions between the inhibitors and SIRT2 at atom level 期刊论文  OAI收割 MOLECULAR SIMULATION, 2020, 卷号: 46, 期号: 8, 页码: 638-649 作者:  Wang, Xiaoyu;  Song, Menghua;  Zhao, Shuang;  Li, Huiyu;  Zhao, Qingjie   |  收藏  |  浏览/下载：33/0  |  提交时间：2020/07/01 SIRT2  inhibitor  molecular dynamics simulation  TCMs  hydrophobic and pi-pi interactions   The mimics of N-epsilon-acyl-lysine derived from cysteine as sirtuin inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 14, 页码: 2375-2378 作者:  Wang, Chun;  Wang, Fang;  Chen, Xiaoxue;  Zou, Yefang;  Zhu, Hong   |  收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 L-Cysteine  The mimics of lysine  Mechanism-based inhibitors  Sirtuin inhibitors  SIRT2 inhibitors   Dichloroacetic acid (DCA) synergizes with the SIRT2 inhibitor Sirtinol and AGK2 to enhance anti-tumor efficacy in non-small cell lung cancer 期刊论文  OAI收割 CANCER BIOLOGY & THERAPY, 2018, 卷号: 19, 期号: 9, 页码: 835-846 作者:  Ma, Wenjing;  Wang, Kaiying;  Huang, Gang;  Zhao, Xiaoping;  Liu, Jianjun   |  收藏  |  浏览/下载：9/0  |  提交时间：2020/12/09 Sodium dichloroacetic acid (DCA)  SIRT2  warburg effect  PDHA1  drug synergy