中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [41]
昆明植物研究所 [4]
上海有机化学研究所 [1]
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期刊论文 [44]
学位论文 [2]
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2023 [2]
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Pharmacolo... [5]
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浏览/检索结果:
共47条,第1-10条
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TPN10475 Constrains Effector T Lymphocytes Activation and Attenuates Experimental Autoimmune Encephalomyelitis Pathogenesis by Facilitating TGF-β Signal Transduction
期刊论文
OAI收割
JOURNAL OF NEUROIMMUNE PHARMACOLOGY, 2024, 卷号: 19, 期号: 1, 页码: 16
作者:
Wang, Chun
;
Jiang, Xiangrui
;
Lv, Jie
;
Zhuang, Wei
;
Xie, Ling
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/04/09
Experimental autoimmune encephalomyelitis
TGF-beta signal transduction
Effector CD4(+) T cells activation
Th/Treg
Cell migration
TPN10475 alleviates concanavalin A-induced autoimmune hepatitis by limiting T cell development and function through inhibition of PI3K-AKT pathway
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 卷号: 125, 页码: 13
作者:
Wang, Chun
;
Han, Mengyao
;
Li, Xinhang
;
Lv, Jie
;
Zhuang, Wei
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/01/16
AIH
T cell
Pro-inflammatory
IFN-gamma
PI3K-AKT
The novel small molecule TPN10518 alleviates EAE pathogenesis by inhibiting AP1 to depress Th1/Th17 cell differentiation
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 卷号: 123, 页码: 12
作者:
Xie, Ling
;
Lv, Jie
;
Saimaier, Kaidireya
;
Han, Sanxing
;
Han, Mengyao
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/10/17
TPN10518
Th1/Th17 cells
AP1
Experimental autoimmune encephalomyelitis
Artemisinin derivative SM934 in the treatment of autoimmune and inflammatory diseases: therapeutic effects and molecular mechanisms
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 7
作者:
Tong, Xiao
;
Chen, Li
;
He, Shi-jun
;
Zuo, Jian-ping
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/09/30
artemisinin derivative
beta-aminoarteether maleate (SM934)
autoimmune and inflammatory diseases
T helper cells
macrophages
inflammatory cytokines
Artemisinin derivative TPN10466 suppresses immune cell migration and Th1/Th17 differentiation to ameliorate disease severity in experimental autoimmune encephalomyelitis
期刊论文
OAI收割
CELLULAR IMMUNOLOGY, 2022, 卷号: 373, 页码: 10
作者:
Liu, Guangyu
;
Jiang, Xiangrui
;
Han, Mengyao
;
Lv, Jie
;
Zhuang, Wei
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/08/16
EAE
Cell migration
Th1
Th17 differentiation
青蒿素-4-芳氨基喹唑啉衍生物体外抗肿瘤机制研究
学位论文
OAI收割
2021
作者:
范东梅
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/03/20
青蒿素-4-芳氨基喹唑啉衍生物体外抗肿瘤机制研究
学位论文
OAI收割
2021
作者:
范东梅
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/03/20
Artemisinin analogue SM934 protects against lupus-associated antiphospholipid syndrome via activation of Nrf2 and its targets
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2021, 页码: 18
作者:
Lin, Zemin
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/05/24
artemisinin analog
antiphospholipid syndrome
antiphospholipid syndrome nephropathy associated lupus nephritis
oxidative stress
inflammation
Nrf2
The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-kB/NLRP3 signaling
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 卷号: 42, 期号: 4, 页码: 593
作者:
Yang Fangming
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/05/22
dry eye disease
artemisinin derivative
β-aminoarteether maleate
inflammation
macrophages
TLR4
inflammasome
The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-kappa B/NLRP3 signaling
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Yang, Fang-ming
;
Fan, Di
;
Yang, Xiao-qian
;
Zhu, Feng-hua
;
Shao, Mei-juan
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2020/12/24
dry eye disease
artemisinin derivative
beta-aminoarteether maleate
inflammation
macrophages
TLR4
inflammasome