中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [18]
西北高原生物研究所 [11]
合肥物质科学研究院 [5]
广州生物医药与健康研... [4]
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期刊论文 [58]
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pH-responsive nanogels with enhanced antioxidant and antitumor activities on drug delivery and smart drug release
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 卷号: 257, 页码: 16
作者:
Ma, Bing
;
Li, Qing
;
Mi, Yingqi
;
Zhang, Jingjing
;
Tan, Wenqiang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Benzimidazole-chitosan quaternary ammonium
salt
Nanogels
pH-responsive
Antioxidant activity
Antitumor activity
Discovery of 2-Aminopyrimidine Derivatives as Potent Dual FLT3/CHK1 Inhibitors with Significantly Reduced hERG Inhibitory Activities
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 23
作者:
Li, Xuemei
;
Wang, Peipei
;
Wang, Chang
;
Jin, Tingting
;
Xu, Ran
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
Discovery of Highly Potent and Selective Thyroid Hormone Receptor βAgonists for the Treatment of Nonalcoholic Steatohepatitis
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 5, 页码: 3284-3300
作者:
Hu, Liuyu
;
Gu, Yipei
;
Liang, Ju
;
Ning, Mengmeng
;
Yang, Junli
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/27
Flavonoids from Hippophae rhamnoides Linn. Revert Doxorubicin-Induced Cardiotoxicity through Inhibition of Mitochondrial Dysfunction in H9c2 Cardiomyoblasts In Vitro
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 4
作者:
Zhou, Wenna
;
Ouyang, Jian
;
Hu, Na
;
Wang, Honglun
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/01
Potential adverse outcome pathways with hazard identification of organophosphate esters
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2022, 卷号: 851, 页码: 13
作者:
Wang, Xiaoqing
;
Li, Fei
;
Teng, Yuefa
;
Ji, Chenglong
;
Wu, Huifeng
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2023/01/11
Organophosphate esters (OPEs)
Network-centric analysis
Risk assessment
Adverse outcome pathway
Quantitative weight of evidence
Pharmaceutical liposomal delivery-specific considerations of innovation and challenges
期刊论文
OAI收割
BIOMATERIALS SCIENCE, 2022, 页码: 14
作者:
Peng, Taoxing
;
Xu, Weihua
;
Li, Qianqian
;
Ding, Yang
;
Huang, Yongzhuo
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/04/10
The combined toxic effects of polyvinyl chloride microplastics and di (2-ethylhexyl) phthalate on the juvenile zebrafish (Danio rerio)
期刊论文
OAI收割
JOURNAL OF HAZARDOUS MATERIALS, 2022, 卷号: 440, 页码: 10
作者:
Wang, Hongdan
;
Wang, Yunqing
;
Wang, Qiaoning
;
Lv, Min
;
Zhao, Xizhen
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/01/26
Microplastics
Embryonic developmental toxicity
Oxidative stress toxicity
Cardiotoxicity effects
Antagonize toxic effects
Luteolin attenuated cisplatin-induced cardiac dysfunction and oxidative stress via modulation of Keap1/Nrf2 signaling pathway
期刊论文
OAI收割
FREE RADICAL RESEARCH, 2022
作者:
Qi, Yajun
;
Fu, Shuang
;
Pei, Donggen
;
Fang, Qilu
;
Xin, Wenxiu
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/12/23
Luteolin
cisplatin
oxidative stress
Keap1
Nrf2
Integrated Transcriptomics and Reverse Pharmacophore Mapping-based Network Pharmacology to Explore the Mechanisms of Natural Compounds against Doxorubicin-induced Cardiotoxicity
期刊论文
OAI收割
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2022, 卷号: 25
作者:
Zhu, Junfeng
;
Yi, Xiaojiao
;
Ding, Haiying
;
Zhong, Like
;
Fang, Luo
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/12/22
Doxorubicin-induced cardiotoxicity
natural compounds
mechanism of action
gene expression profile
bioinformatics
network pharmacology
Cardiotoxicity of Epidermal Growth Factor Receptor 2-Targeted Drugs for Breast Cancer
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 12
作者:
Yang, ZiYan
;
Wang, Wei
;
Wang, Xiaojia
;
Qin, ZhiQuan
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2022/01/10
cardiotoxicity
ErbB2
targeting drugs
breast cancer
therapy