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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [13]
新疆理化技术研究所 [1]
中国科学院大学 [1]
采集方式
OAI收割 [14]
iSwitch采集 [1]
内容类型
期刊论文 [15]
发表日期
2021 [1]
2020 [1]
2019 [1]
2018 [2]
2017 [2]
2016 [1]
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TPN672: A Novel Serotonin-Dopamine Receptor Modulator for the Treatment of Schizophrenia
期刊论文
OAI收割
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2021, 卷号: 378, 期号: 1, 页码: 20-30
作者:
Wang, Yu
;
He, Yang
;
Yang, Feipu
;
Abame, Melkamu Alemu
;
Wu, Chunhui
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/11/04
Automated design and optimization of multitarget schizophrenia drug candidates by deep learning
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 204, 页码: 16
作者:
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收藏
  |  
浏览/下载:52/0
  |  
提交时间:2020/12/21
Schizophrenia
Multitarget antipsychotic drugs
Recurrent neural network
Multitask deep neural network
Automated drug design
Continuation of structure-activity relationship study of novel benzamide derivatives as potential antipsychotics
期刊论文
OAI收割
ARCHIV DER PHARMAZIE, 2019, 卷号: 352, 期号: 4, 页码: 13
作者:
Xu, Mingshuo
;
Guo, Shuang
;
Yang, Feipu
;
Wang, Yu
;
Wu, Chunhui
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
5-HT1A
5-HT2A
catalepsy
D-2
PCP-induced hyperactivity
Synthesis and biological evaluation of a series of novel pyridinecarboxamides as potential multi-receptor antipsychotic drugs
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 4, 页码: 606-611
作者:
Xu, Mingshuo
;
Wang, Yu
;
Yang, Feipu
;
Wu, Chunhui
;
Wang, Zhen
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/01/08
Antipsychotic
Multi-receptor
Pyridinecarboxamide
5-HT1A receptor
PCP-induced hyperlocomotion
Synthesis and biological evaluation of a series of multi-target N-substituted cyclic imide derivatives with potential antipsychotic effect
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 145, 页码: 74-85
作者:
Xu, Mingshuo
;
Wang, Yu
;
Yang, Feipu
;
Wu, Chunhui
;
Wang, Zhen
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2019/01/08
Antipsychotic
Cyclic imide
Multi-target
5-HT1A receptor
Synthesis and biological investigation of tetrahydropyridopyrimidinone derivatives as potential multireceptor atypical antipsychotics
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 17, 页码: 4904-4916
作者:
Xiamuxi, Hainimu
;
Wang, Zhen
;
Li, Jianfeng
;
Wang, Yu
;
Wu, Chunhui
  |  
收藏
  |  
浏览/下载:119/0
  |  
提交时间:2019/01/08
Dopamine
Serotonin
Multireceptor
Atypical antipsychotic
5-HT1A
Synthesis and biological investigation of tetrahydropyridopyrimidinone derivatives as potential multireceptor atypical antipsychotics
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 17, 页码: 4904-4916
作者:
Xiamuxi, H (Xiamuxi, Hainimu)
;
Wang, Z (Wang, Zhen)
;
Li, JF (Li, Jianfeng)
;
Wang, Y (Wang, Yu)
;
Wu, CH (Wu, Chunhui)
  |  
收藏
  |  
浏览/下载:110/0
  |  
提交时间:2017/10/31
Dopamine
Serotonin
Multireceptor
Atypical Antipsychotic
5-ht1a
Synthesis, structure-activity relationships, and biological evaluation of a series of benzamides as potential multireceptor antipsychotics
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 13, 页码: 3141-3147
作者:
Yang, Feipu
;
Jiang, Xiangrui
;
Li, Jianfeng
;
Wang, Yu
;
Liu, Yongjian
  |  
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2019/01/08
D-2
5-HT1A
5-HT2A
PCP-induced hyperactivity
Catalepsy
Dual Ligands Targeting Dopamine D-2 and Serotonin 5-HT1A Receptors as New Antipsychotical or Anti-Parkinsonian Agents
期刊论文
OAI收割
CURRENT MEDICINAL CHEMISTRY, 2014, 卷号: 21, 期号: 4, 页码: 437-457
作者:
Ye, Na
;
Song, Zilan
;
Zhang, Ao
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
Atypical antipsychotics
dopamine D-2 receptor
dual ligands
Parkinson's disease
Schizophrenia
Serotonin 5-HT1A receptor
Paradoxical effects of very low dose mk-801
期刊论文
iSwitch采集
European journal of pharmacology, 2006, 卷号: 537, 期号: 1-3, 页码: 77-84
作者:
Tang, YJ
;
Zou, H
;
Strong, JA
;
Cui, YW
;
Xie, QP
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/05/10
Dizocilpine maleate
Nmda receptor antagonist
Locomotion
Immobility
Catalepsy
Haloperidol